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Damaged mitochondria use 'eat me' signals for mitophagy

When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them.

12 Apr 2019

Unisex, hormone-free contraceptive pill on the horizon

Side effects from hormonal contraceptives are common. That’s why one start-up is developing a hormone-free contraceptive that can be used by both men and women.

12 Apr 2019

Study finds wide variations in Medicaid reimbursements for radiation therapies

A new study finds wide state-by-state variations in Medicaid reimbursements to physicians who treat cancer patients with radiation therapies.

12 Apr 2019

USC researchers report breakthrough to prevent osteonecrosis of the jaw

USC researchers and collaborators report a breakthrough to prevent damage to the jaw, a side effect suffered by some people undergoing treatment for cancer or osteoporosis.

11 Apr 2019

Experimental drug may be twice as good at fighting vision loss as previously thought

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.

11 Apr 2019

Characterizing Small Molecules with NMR

In this interview, Marcel Lachenmann describes the importance of characterizing small molecules in the pharma, food and polymer industry and how NMR achieves this.

From Oxford Instruments - Life Sciences 11 Apr 2019

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

The influence of an active lifestyle on the regenerative capacity of the peripheral nervous system, that is, the set of cranial and spinal nerves that control motor and sensory functions, is described here for the first time, explains Ángel Barco, who has led the participation of the Institute of Neurosciences UMH-CSIC, in Alicante, in this international study.

11 Apr 2019

GARDP forms multi-actor partnerships to discover new antibiotics

Multi-actor partnership tests natural products and compound libraries for antibacterial activity Discovery efforts will focus on World Health Organization's priority pathogens The Global Antibiotic Research and Development Partnership is partnering with Calibr, the Helmholtz Centre for Infection Research, in particular its location Helmholtz-Institute for Pharmaceutical Research Saarland, and the University of Queensland's Community for Open Antimicrobial Drug Discovery in its efforts to develop and ensure new antibiotics are globally available to all patients who need them.

11 Apr 2019

Processed aconite root could relieve neuropathic pain in murine peripheral neuropathy

The root of Aconitum carmichaeli, is a crude drug used in traditional Chinese or Japanese kampo medicine to treat pain associated with coldness.

11 Apr 2019

Scientists develop technique to clear abnormal tau protein from human neurons

Harnessing a probe used to image the brain in diagnosing Alzheimer's disease and related forms of dementia, scientists at Dana-Farber Cancer Institute and Massachusetts General Hospital have successfully cleared patient-derived brain cells of an abnormal protein associated with dementia and other neurogenerative disorders.

10 Apr 2019

Common food preservative could make flu vaccine less effective

A preservative commonly used to increase the shelf life of food products may weaken the body’s immune defense against influenza, thus reducing the response to the flu vaccine.

9 Apr 2019

New hope for treating devastating brain cancer in children

There could be new treatments on the horizon for diffuse intrinsic pontine glioma, or DIPG, a devastating form of brain cancer that afflicts young children and is currently incurable.

5 Apr 2019

Researchers isolate compound that kills drug-resistant fungi from ant microbiota

Antimicrobial and antifungal resistance, which describe the ability of bacteria and other pathogens to resist the effects of drugs to which they were once sensitive, is a major public health problem worldwide.

5 Apr 2019

Researchers synthesize new polysulfide donor that has high anti-inflammatory effect

Researchers from Japan have developed a new polysulfide donor: a chemical compound composed of chains of sulfur atoms that can artificially increase reactive sulfur species (chemically reactive molecules containing sulfur) in cells and tissues.

4 Apr 2019

Researchers unravel 3D structure of key molecular target for cancer treatment

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment.

4 Apr 2019

New immune-based therapy eliminates HPV in one-third of women with cervical precancerous lesions

A potential new immune-based therapy to treat precancers in the cervix completely eliminated both the lesion and the underlying HPV infection in a third of women enrolled in a clinical trial.

4 Apr 2019

Researchers use metal-free catalyst to synthesize ketone from aldehyde

Ketones are important organic compounds found in a variety of pharmaceuticals, agrochemicals, and natural products.

4 Apr 2019

Compounds derived from common hop plant thwart cancer cells

The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well, new research at Oregon State University shows.

3 Apr 2019

Researchers synthesize nanocluster made of 32 gold atoms

Researchers have synthesized a tiny structure from 32 gold atoms.

2 Apr 2019

Colorado compound dramatically affects cancer metastasis

Many cancers are relatively harmless at their site of origin, and it is only when they metastasize to sites like the brain, bones, lungs, and liver that they become especially dangerous.

1 Apr 2019