Enzyme News and Research

RSS

Novel therapy using nitric oxide may be an efficient and safe way to treat multiple metabolic diseases

A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet.

29 Apr 2022

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

A new study describes the development of new molecules with inhibitory activity against the SARS-CoV-2 viral main protease (Mpro) enzyme, based on rattlesnake venom.

29 Apr 2022

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

In a new study, researchers described their self-designed chimeric receptor-binding domain-dimer vaccine approach to adapt SARS-CoV-2 variants of concern and variants of interest.

29 Apr 2022

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers examined the efficiency of the main protease (Mpro) inhibitor against SARS-CoV-2.

29 Apr 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

A recent study demonstrated that the phytochemical curcumin is a potent therapeutic prospect against the SARS-CoV-2 Omicron variant

29 Apr 2022

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

As sessile organisms, plants have to continually adapt their growth and architecture to the ever-changing environment. To do so, plants have evolved distinct molecular mechanisms to sense and respond to the environment and integrate the signals from outside with endogenous developmental programs.

28 Apr 2022

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Massachusetts General Hospital researchers have developed a novel treatment strategy that has the potential to bring the life-saving benefits of chimeric antigen receptor T-cell therapy (CAR T) to patients with acute myeloid leukemia (AML) the most common form of leukemia in adults.

28 Apr 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

Discovery of novel antibody that targets shared epitope on SARS-CoV-2 variants

Researchers assessed the antibody responses elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and defined the epitopes shared by them.

28 Apr 2022

Green tea catechin as pan-coronavirus attachment inhibitor

In a recent study posted to the Research Square* preprint server, researchers assessed the impact of green tea catechin epigallocatechin gallate (EGCG) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2022

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

Researchers assessed the epigenetic aging in COVID-19 patients and its impact on COVID-19 severity by a genome-wide deoxyribonucleic acid methylation profiling analysis.

27 Apr 2022

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The current study, escribes a new mAb LY-CoV1404 (bebtelovimab) from Eli Lilly, with high neutralization potency with a broad spectrum of activity across all current variants.

27 Apr 2022

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

In a study published in Cells, researchers have been investigating the effects of this extract for use against COVID-19.

27 Apr 2022

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Researchers revealed that native FokI relaxation might be induced, resulting in FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids.

27 Apr 2022

Cellular reprogramming can lead to better liver tissue regeneration in mice

Mammals can't typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset liver cells to more youthful states - allowing them to heal damaged tissue at a faster rate than previously observed.

27 Apr 2022

Superior T-cell immunity in COVID vaccinated

A recent study published in the journal Public Library of Science (PLOS) ONE presented the T cell and humoral immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and infection against the SARS-CoV-2 original and mutant strains.

27 Apr 2022

Asymptomatic SARS-CoV-2 infection among research personnel: Study

A recent research paper published in the journal Public Library of Science (PLOS) ONE analyzed asymptomatic coronavirus disease 2019 (COVID-19) in personnel engaged in academic study.

26 Apr 2022

Enzyme News and Research

Novel therapy using nitric oxide may be an efficient and safe way to treat multiple metabolic diseases

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Unraveling how strigoractone hormone regulates massive gene networks controlling plant growth

Novel method could bring life-saving benefits of CAR T-cell therapy to patients with acute myeloid leukemia

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Discovery of novel antibody that targets shared epitope on SARS-CoV-2 variants

Green tea catechin as pan-coronavirus attachment inhibitor

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

Bebtelovimab potently neutralizes all SARS-CoV-2 variants of concern

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Cellular reprogramming can lead to better liver tissue regeneration in mice

Superior T-cell immunity in COVID vaccinated

Asymptomatic SARS-CoV-2 infection among research personnel: Study

Measuring Drug-Target Residence Times with Biochemical Assays eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo