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New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

CReM researchers optimize process to engineer disease- or patient-specific lung stem cells

The Center for Regenerative Medicine at Boston University and Boston Medical Center has engineered two new categories of lung epithelial cells in vitro using pluripotent stem cells.

12 Apr 2018

Researchers review potential of targeted nanocarriers to revolutionize cancer care

A new Tel Aviv University study addresses the challenges of nanoparticle-based cancer-targeting strategies. It also suggests ways of refocusing the collaborative work of cancer researchers and clinicians to move the field forward from "the bench" to the patients.

12 Apr 2018

CU Anschutz scientists receive $3.8 million DoD grant to boost EB research

Scientists from the Gates Center for Regenerative Medicine at the University of Colorado School of Medicine are part of a consortium awarded $3.8 million from the U.S. Department of Defense to move discoveries in stem cell-created skin grafts into the manufacturing stage, bringing further hope to victims of debilitating inherited skin diseases.

12 Apr 2018

Researchers show how highly contagious norovirus infection starts in mice

Norovirus – the highly contagious gastrointestinal illness best known for spreading rapidly on cruise chips, in nursing homes, schools and other densely populated spaces – kills an estimated 200,000 people annually, mostly in the developing world.

12 Apr 2018

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Why does drinking alcohol or consuming sugar make us thirsty? An international study of mice in Texas and humans in Europe reveals an unexpected anti-dehydration mechanism.

12 Apr 2018

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

Researchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung.

12 Apr 2018

UCLA scientists identify four subtypes of melanoma with different drug sensitivities

Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states - that is, to regress to an earlier stage of development - which can lead it to become resistant to treatment.

12 Apr 2018

New population of lung stem cells may be key for regenerating airways after injury

The human airway is a system of branching tubes that connects the nose and mouth with the lungs and allows us to inhale air, extract the vital oxygen, and exhale the waste product carbon dioxide.

12 Apr 2018

High carbohydrate and sugar linked to disease recurrence, death in head and neck cancer patients

Consuming high amounts of carbohydrates and various forms of sugar during the year prior to treatment for head and neck cancer may increase patients' risks of cancer recurrence and mortality, a new study reports.

12 Apr 2018

Dietary fats play varied roles in disease

This month's issue of the Journal of Lipid Research features studies examining how fats in the diet affect health, including whether the ketogenic diet is a reasonable cancer therapy; how the type of unsaturated fats in a mouse's chow affects inflammation; and how cells respond to nutrient signals.

12 Apr 2018

Aberrant protein prevents self-cleaning of nerve cells in ALS

Scientists have discovered that TDP-43 interferes with lysosomal pathways responsible for its clearance and induces autophagy in ALS.

12 Apr 2018

Researchers develop thin, flexible polymers to record activity more deeply in the brain

Science has yet to unravel a complete understanding of the brain and all its intricate workings. It's not for lack of effort.

11 Apr 2018

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Scientists at the University of Wyoming have found that mice engineered to have Huntington's disease (HD) have an over-accumulation of iron in their mitochondria.

11 Apr 2018

Experimental peptide drug shows promise against acute myeloid leukemia

In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide drug shows promise against the often-lethal cancer acute myeloid leukemia and describe how the drug works at the molecular level.

11 Apr 2018

NIGMS-funded researcher finds new technique to track cell’s movement

Cells are the basis of the living world. Our cells make up the tissues and organs of our bodies. Bacteria are also cells, living sometimes alone and sometimes in groups called biofilms. We think of cells mostly as staying in one spot, quietly doing their work. But in many situations, cells move, often very quickly.

11 Apr 2018

Researchers develop new technique to study self-assembling virus shell

Northwestern Engineering researchers have developed a new way to manipulate a virus shell that self-assembles from proteins and holds promise as a carrier for disease detection, drug delivery, and vaccinations.

11 Apr 2018

Ludwig scientists develop and test individualized ovarian cancer vaccine

A Ludwig Cancer Research study has shown that an entirely new type of personalized cancer vaccine induces novel, potent and clinically effective immune responses in patients receiving a combination of standard therapies for recurrent, stage III and IV ovarian cancer.

11 Apr 2018

New cancer vaccine yields promising results in clinical study

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

11 Apr 2018

Sweet tooth gene linked to less body fat, research shows

People with a gene variation of FGF21 have a predisposition to less body fat than others, new research conducted at the University of Copenhagen, among others, shows.

11 Apr 2018

B Cell News and Research

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

CReM researchers optimize process to engineer disease- or patient-specific lung stem cells

Researchers review potential of targeted nanocarriers to revolutionize cancer care

CU Anschutz scientists receive $3.8 million DoD grant to boost EB research

Researchers show how highly contagious norovirus infection starts in mice

Study reveals unexpected mechanism that induces thirst after alcohol or sugar exposure

Targeting metabolism of key nutrients could be effective in treating squamous cell carcinoma

UCLA scientists identify four subtypes of melanoma with different drug sensitivities

New population of lung stem cells may be key for regenerating airways after injury

High carbohydrate and sugar linked to disease recurrence, death in head and neck cancer patients

Dietary fats play varied roles in disease

Aberrant protein prevents self-cleaning of nerve cells in ALS

Researchers develop thin, flexible polymers to record activity more deeply in the brain

Scientists find link between over-accumulation of mitochondrial iron and Huntington's disease

Experimental peptide drug shows promise against acute myeloid leukemia

NIGMS-funded researcher finds new technique to track cell’s movement

Researchers develop new technique to study self-assembling virus shell

Ludwig scientists develop and test individualized ovarian cancer vaccine

New cancer vaccine yields promising results in clinical study

Sweet tooth gene linked to less body fat, research shows

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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