Antibiotic Resistance News and Research

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Researchers use XAI to unlock secrets of drug discovery

Artificial intelligence (AI) has exploded in popularity. It powers models that help us drive vehicles, proofread emails and even design new molecules for medications.

18 Aug 2024

Uncovering the mechanisms behind bacterial cell shape and potential antibiotic targets

In what they labeled a "surprising" finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape.

16 Aug 2024

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

Cesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site.

14 Aug 2024

C-Path awards grant to UT Austin professor for groundbreaking antibiotic resistance research

Critical Path Institute's (C-Path) Translational Therapeutics Accelerator (TRxA) announced today that Kenneth Keiler, Ph.D., Professor of Molecular Biosciences at the University of Texas at Austin, has been awarded a research grant for his innovative project titled "Inhibitors of the Gram-negative Cell Envelope Stress Response as Anti-Infectives and Antibiotics."

13 Aug 2024

New review suggests balanced biocide use for sustainability and health benefits

A recent review in the journal Sustainable Microbiology discusses how the use of biocides can promote well-being - but must only be used when there are clear benefits.

9 Aug 2024

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Emory researcher David Weiss has spent years studying a baffling phenomenon called heteroresistance, in which a tiny fraction of bacteria remain resistant to antibiotics, while the remainder succumb.

2 Aug 2024

Study reveals how coinfecting phages impede each other’s entry into bacterial cells

The process by which phages - viruses that infect and replicate within bacteria - enter cells has been studied for over 50 years.

2 Aug 2024

Challenging antibiotic resistance with dual-action macrolones

A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research from the University of Illinois Chicago.

24 Jul 2024

E. coli genomic analysis uncovers antibiotic resistance mechanisms in dogs

Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.

16 Jul 2024

Over-the-counter nasal sprays cut respiratory infections by 20%, study finds

Widely available over-the counter nasal sprays could keep upper respiratory tract infections - like colds, chest infections, flu, sore throat, and sinus infections - at bay, and prevent full-blown symptoms from developing, one of the largest trials to date to test their effectiveness finds.

12 Jul 2024

Researchers develop a simple new way to store, identify, and share phages

The great promise of bacteriophages is that they naturally destroy bacteria, often in situations where antibiotics fail.

12 Jul 2024

Gut microbiome health crucial to survival after solid organ transplants

'Unhealthy' gut microbiome patterns are linked to a heightened risk of death after a solid organ transplant, finds research published online in the journal Gut.

9 Jul 2024

Pentamidine: A promising prophylactic against chlamydial infections

Despite the significant increase in sexually transmitted diseases in recent years, there is currently no vaccine available against common bacterial pathogens such as chlamydia.

9 Jul 2024

Mapping pathogen spread and evolution using genomic and human mobility data

A new way to map the spread and evolution of pathogens, and their responses to vaccines and antibiotics, will provide key insights to help predict and prevent future outbreaks.

3 Jul 2024

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Antibiotics are a cornerstone of modern medicine. They are regularly used to treat bacterial infections or as a prophylactic measure during surgery to prevent infection.

3 Jul 2024

Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for developing new antibiotic treatments.

2 Jul 2024

Antibiotic Resistance News and Research

Researchers use XAI to unlock secrets of drug discovery

Uncovering the mechanisms behind bacterial cell shape and potential antibiotic targets

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

C-Path awards grant to UT Austin professor for groundbreaking antibiotic resistance research

New review suggests balanced biocide use for sustainability and health benefits

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Study reveals how coinfecting phages impede each other’s entry into bacterial cells

Challenging antibiotic resistance with dual-action macrolones

E. coli genomic analysis uncovers antibiotic resistance mechanisms in dogs

Over-the-counter nasal sprays cut respiratory infections by 20%, study finds

Researchers develop a simple new way to store, identify, and share phages

Gut microbiome health crucial to survival after solid organ transplants

Pentamidine: A promising prophylactic against chlamydial infections

Mapping pathogen spread and evolution using genomic and human mobility data

New research highlights potential of antimicrobial peptide mixtures to inhibit drug resistance

Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

Taxing broad-spectrum antibiotics could be a strategy to combat antibiotic resistance

Study provides new clues in the understanding of how antibiotic resistance spreads

Novel approach can make many more bacteria amenable to genetic engineering

Chimpanzees seek out tree bark and ferns with medicinal benefits, researchers discover

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