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Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

C-Path releases new publication on transforming drug development for neurological disorders

Critical Path Institute (C-Path) is pleased to announce the release of a new peer-reviewed publication, titled "Transforming Drug Development for Neurological Disorders: Proceedings from a Multi-disease Area Workshop," now published in Neurotherapeutics, The Journal of the American Society for Experimental Neurotherapeutics.

9 Nov 2023

Laser hair removal reduces the risk of recurrence in patients with pilonidal disease

Laser epilation, commonly known as laser hair removal, reduced the risk of recurrence in patients with pilonidal disease, an inflammatory, painful, and sometimes chronic or recurring condition, according to research conducted by Peter C. Minneci, M.D., Chair of Surgery at Nemours Children's Health, Delaware Valley, and published in JAMA Surgery.

9 Nov 2023

Individuals with severe mental illness are at higher risk of experiencing physical multimorbidity

A new study published in BMJ Mental Health has found that individuals with severe mental illness are almost twice as likely to report physical multimorbidity, emphasizing the critical importance of addressing the intersection between mental and physical health.

9 Nov 2023

An Arm and a Leg: ‘Your Money or Your Life’: This doctor wrote the book on medical debt

In 2019, emergency medicine physician and historian Luke Messac was working as a medical resident.

9 Nov 2023

Underdiagnosed and undertreated, young Black males with ADHD get left behind

As a kid, Wesley Jackson Wade should have been set up to succeed. His father was a novelist and corporate sales director and his mother was a special education teacher.

9 Nov 2023

Fluoride and sealants win against youth dental caries, a robust review informs US health policy

In a comprehensive review for the JAMA Network, researchers find that preventive oral health interventions like fluoride treatments and sealants are effective in combating dental caries in youth, offering actionable insights for the US Preventive Services Task Force and healthcare providers.

8 Nov 2023

Study unravels molecular basis of chronic pain transition

Researchers from the Center for Translational Immunology at University Medical Center Utrecht (the Netherlands) have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution.

8 Nov 2023

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation that leads to pain, joint damage, and disability, which affects approximately 18 million people worldwide.

8 Nov 2023

Experts develop equitable quality measures to improve lupus care by 2030

Leaders of a project to develop and implement equitable new quality measures for lupus care by the end of the decade will present their work at ACR Convergence 2023, the American College of Rheumatology's annual meeting.

7 Nov 2023

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD) that affect the gastrointestinal tract.

7 Nov 2023

Lario Therapeutics receives “Company Making a Difference Award” from CDLK5 Forum, recognising its unique approach to precision medicine for genetic epilepsies

“CDLK5 Forum Award for Excellence - Company Making a Difference 2023 Pre-clinical” presented by the Loulou Foundation at the CDKL5 Forum, 6th-7th November in London

7 Nov 2023

Study shows depression increases disability risk in rheumatoid arthritis sufferers

The interactions between rheumatoid arthritis (RA) and major depressive disorder (MDD).

7 Nov 2023

Blood test predicts MS disability worsening up to two years in advance

Multiple sclerosis patients whose blood tests reveal elevated NfL, a biomarker of nerve damage, could see worsening disability one to two years later, according to a new study spearheaded by researchers at UC San Francisco.

6 Nov 2023

New pathway to combat cardiovascular disease identified

Research led by the University of Minnesota Medical School identified a new pathway to combat cardiovascular disease. The study was recently published in Nature Cardiovascular Research.

3 Nov 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Tufts researchers explore the science of aging

Anti-wrinkle creams, superfoods that keep you young, dietary supplements that promise improved memory, "immortal" cells that can renew themselves forever-;in our stores and media, claims about aging abound.

2 Nov 2023

Gene editing breakthrough could offer new hope for people with phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

2 Nov 2023

Study highlights disparities in stroke care across socioeconomic groups

People who live in neighborhoods with lower socioeconomic status are less likely to receive clot-busting medications or undergo clot-removing procedures after they have a stroke than people who live in neighborhoods with higher socioeconomic status, according to a study published in the November 1, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

1 Nov 2023

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Researchers aimed to identify dependable protein biomarkers for multiple sclerosis (MS).

1 Nov 2023

Disability News and Research

Study reveals early role of SYNGAP1 gene in brain development

C-Path releases new publication on transforming drug development for neurological disorders

Laser hair removal reduces the risk of recurrence in patients with pilonidal disease

Individuals with severe mental illness are at higher risk of experiencing physical multimorbidity

An Arm and a Leg: ‘Your Money or Your Life’: This doctor wrote the book on medical debt

Underdiagnosed and undertreated, young Black males with ADHD get left behind

Fluoride and sealants win against youth dental caries, a robust review informs US health policy

Study unravels molecular basis of chronic pain transition

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Experts develop equitable quality measures to improve lupus care by 2030

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Lario Therapeutics receives “Company Making a Difference Award” from CDLK5 Forum, recognising its unique approach to precision medicine for genetic epilepsies

Study shows depression increases disability risk in rheumatoid arthritis sufferers

Blood test predicts MS disability worsening up to two years in advance

New pathway to combat cardiovascular disease identified

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Tufts researchers explore the science of aging

Gene editing breakthrough could offer new hope for people with phenylketonuria

Study highlights disparities in stroke care across socioeconomic groups

Researchers identify key protein biomarkers in MS patients, paving way for personalized treatment strategies

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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