Polymerase News and Research

RSS

Potential antitumoral effects of Manuka honey in breast cancer models

Researchers evaluated the antitumor activity of Manuka honey on human breast cancer cells and its underlying molecular mechanisms in both in vitro and in vivo preclinical models.

22 Aug 2024

Study links symptomatic chlamydia to higher risk of reproductive complications

The risks of reproductive complications after asymptomatic and symptomatic infections with Chlamydia trachomatis (chlamydia).

21 Aug 2024

Study reveals how avian flu adapts to mammalian cells

In recent years, public health measures, surveillance, and vaccination have helped bring about significant progress in reducing the impact of seasonal flu epidemics, caused by human influenza viruses A and B.

19 Aug 2024

Researchers reveal why a diet rich in magnesium is so important for your health

Researchers examined whether magnesium deficiency in the healthy middle-aged Australian population was independently or in combination with increased homocysteine levels associated with in vivo DNA damage.

15 Aug 2024

New research gives unprecedented view of colorectal cancer genetic makeup

Researchers provided a comprehensive genomic characterization of colorectal carcinoma, a type of cancer that starts in the colon or rectum, through whole-genome sequencing of 2,023 samples, identifying novel driver genes, molecular subgroups, and potential clinical implications.

15 Aug 2024

Valproic acid shows promise in reducing COVID-19 severity and hospitalization

Researchers found that valproic acid (VPA), especially when combined with DHA, significantly reduces SARS-CoV-2 infection rates and severity, potentially activating antiviral mechanisms. Epidemiologic data support VPA's role in reducing COVID-19 severity and hospitalization rates.

6 Aug 2024

Upper respiratory microbiome shows age, sex, and lifestyle impacts, study finds

A Dutch study analyzed the upper respiratory tract microbiome across various age groups, finding significant associations between microbial composition, age, sex, and lifestyle factors like smoking and antibiotic use.

5 Aug 2024

Mucosal COVID-19 vaccine prevents airborne transmission of SARS-CoV-2

The impact of mucosal versus intramuscular vaccine immunization on airborne infection and transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Syrian hamsters.

5 Aug 2024

How machine learning is accelerating research in structural biology

For Lucas Farnung, there is no question more fascinating than how a single fertilized egg develops into a fully-functioning human.

2 Aug 2024

Triptolide-based treatment prolongs symptom-free survival in preclinical medulloblastoma models

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models – all without showing signs of toxicity.

1 Aug 2024

New studies reveal common DNA replication mechanisms in humans and yeast

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies published in the journals Science and Proceedings of the National Academy of Sciences.

1 Aug 2024

UC San Diego develops AI tool for rapid, low-cost detection of genomic alterations in cancer

A new generation of artificial intelligence (AI) tools designed to allow rapid, low-cost detection of clinically actionable genomic alterations directly from tumor biopsy slides has been developed by a team led by engineers and medical researchers at University of California San Diego.

1 Aug 2024

COVID-19 significantly increases risk of hearing loss in young adults, study finds

Young adults with COVID-19 face a significantly higher risk of hearing loss and sudden sensorineural hearing loss. Researchers urge awareness and further investigation into COVID-19-related auditory damage.

31 Jul 2024

Vegan diet may slow aging

Vegan diets showed short-term benefits on epigenetic aging compared to omnivorous diets in healthy twins, with reduced epigenetic age metrics observed in the vegan group. However, telomere length and overall mitotic clock values remained unchanged for both diets.

31 Jul 2024

Wildlife species show high SARS-CoV-2 exposure linked to human activity

Researchers found SARS-CoV-2 RNA in six wildlife species and higher seroprevalence in high human activity areas. Seven new human-to-animal transmission events of the Omicron variant were identified.

30 Jul 2024

Garlic as a potent weapon against atherosclerosis

Researchers identified garlic's potential to treat atherosclerosis by regulating ferroptosis and reducing lipid peroxidation, offering a safer alternative to current treatments.

29 Jul 2024

Wearing surgical face masks in public spaces reduces the risk of self-reported respiratory symptoms

A team of Norwegian researchers conducted a pragmatic randomized trial to examine whether wearing surgical face masks while in public spaces resulted in a lower incidence of self-reported respiratory infection symptoms than not wearing a face mask.

29 Jul 2024

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Research shows human cytomegalovirus (CMV) reactivation in breast milk affects milk composition, infant gut microbiome, and growth, with potential impacts on neonatal health.

28 Jul 2024

Alarming spread of H5N1 bird flu in US dairy cattle reveals cross-species transmission dangers

Researchers discovered that the H5N1 avian influenza virus has spilled over into dairy cattle in the US, posing significant cross-species transmission risks. Their multidisciplinary study reveals the virus's evolution and its zoonotic potential, emphasizing the need for heightened biosecurity measures.

25 Jul 2024

Long-term immune changes persist in unvaccinated COVID-19 patients

Study reveals that unvaccinated individuals experience significant long-term changes in immune parameters up to ten months post-COVID-19 infection, with a shift towards a Th2 cytokine profile.

21 Jul 2024