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Polyglycine aggregates disrupt tRNA splicing and drive neurodegeneration

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

17 Jul 2025

Uncovering a protective RNA molecule in kidney stress and disease

Cells contain helper molecules called transfer RNAs (tRNAs), which carry building blocks (amino acids) to make proteins.

17 Jul 2025

Challenges in identifying high risk patients for preeclampsia using USPSTF guidelines

Preeclampsia (PE) is a hypertensive disease that complicates 7-10% of pregnancies. While recent advances in understanding the underlying causes of PE have been made, predicting its occurrence has historically been difficult because it is a complex condition that likely results from a variety of causes and can present in different ways.

17 Jul 2025

endTB-Q trial highlights importance of individualized regimens

Some patients with highly drug-resistant tuberculosis could benefit from a shorter treatment with fewer drugs while others may warrant more aggressive therapy, according to the findings of a new study led by an international group of researchers including scientists from Harvard Medical School and conducted across six countries in Asia, Africa, and South America.

17 Jul 2025

Chemotherapy may trigger inflammatory response that fuels bladder cancer resistance

Chemotherapy used to target and kill bladder cancer cells may trigger an inflammatory response that ultimately may make the cancer more resistant to treatment, according to new research from scientists at Houston Methodist.

16 Jul 2025

Extracellular vesicle RNA reveals clues about obesity and metabolic disease

Our study examines how RNA in extracellular vesicles (EVs) can provide insights into metabolic phenotypes related to obesity. By using functional genomics approaches, we found a high representation of genes and regulatory elements previously associated with obesity and type 2 diabetes represented by the RNA cargo within these EVs.

15 Jul 2025

Americans divided on how to manage neck and back pain, survey reveals

New survey data from the Orlando Health Spine Center reveals a significant difference among Americans on how to manage neck and back pain.

15 Jul 2025

Vested interests. Influence muscle. At RFK Jr.’s HHS, It’s not pharma. It’s wellness.

On his way to an Ultimate Fighting Championship event, Health and Human Services Secretary Robert F. Kennedy Jr. stopped by the home of podcaster Gary Brecka.

14 Jul 2025

Oral health function linked to markers of lifestyle-related diseases in older adults

The term 'oral health' refers to the health of the mouth, teeth, gums, and other related structures, and it is closely linked with our well-being and quality of life.

12 Jul 2025

Lower body temperature found to directly influence glucose metabolism in mice

Some mammals are capable of hibernating during periods of low food availability in an effort to conserve energy and survive.

10 Jul 2025

Why vitamin B6 could raise the risk of hypoglycemia for people with diabetes

A large-scale Mendelian randomization study found no genetic evidence that vitamins A, C, or D reduce the risk of major diabetic complications. However, higher genetically predicted vitamin B6 levels were strongly associated with increased risk of diabetic hypoglycemia, warranting caution with supplementation.

8 Jul 2025

Surprising risks found in popular cinnamon brands across Europe

A Europe-wide analysis of 104 retail cinnamon samples found that only one-third met quality, safety, and authenticity standards. Most Ceylon cinnamon samples showed signs of adulteration, contamination, or non-compliance with regulations.

8 Jul 2025

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary.

2 Jul 2025

Embryos from women with PCOS carry distinctive epigenetic memory

Novel research presented today at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) has found that embryos from women with polycystic ovary syndrome (PCOS) carry a distinctive 'epigenetic memory' that could explain why the condition often runs in families.

1 Jul 2025

Teaching emotional skills improves student wellbeing in Japan

Today, high school students worldwide face unprecedented levels of stress as they navigate academic pressures, issues with social identity, and future career decisions.

26 Jun 2025

Medicaid cuts threaten health care access in rural America

Major cuts to Medicaid funding could have rural communities across the country facing widespread hospital closures and reduced access to health care, says Michael Shepherd, a health policy researcher at the University of Michigan.

25 Jun 2025

Uncovering hidden disease clues with nanoparticles and AI

Imagine Spartan Stadium packed with 75,000 fans, all wearing green and white jerseys - except one person in a solid green shirt.

24 Jun 2025

Mayo Clinic researchers discover how ovarian cancer may begin

Little is known about what causes ovarian cancer, and there is no way to detect it early yet. About 75% of the time when someone is diagnosed with ovarian cancer, it has already progressed to stage 3 or stage 4, which means it has spread to other parts of the body.

24 Jun 2025

Flies on dairy farms act as hidden carriers of superbugs and zoonotic threats

Researchers used deep metagenomic sequencing to trace zoonotic pathogens and antibiotic resistance genes from cow manure into the guts of muscid flies on a French dairy farm. Findings reveal that flies not only carry but may amplify dangerous microbes, underscoring public health risks.

22 Jun 2025

New RSV guideline aims to standardize pediatric care across China

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory infections (ALRTIs) in children under five and poses a persistent threat to child health worldwide.

20 Jun 2025