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Immune cell navigation breakthrough offers hope for better anti-inflammatory drugs

A scientific collaboration between the University of Bath (UK) and the UMass Chan Medical School (USA) have determined how a specific type of white blood cells, called neutrophils, move through the body.

31 Jul 2026

Soy lysolecithin reduces salt-induced hypertension and cognitive decline

High salt (HS) intake is a major global health concern, closely linked to hypertension and growing evidence of cognitive and emotional decline.

31 Jul 2026

New research explains how embryos establish germline cell boundaries

Every embryo of an organism that reproduces sexually faces an early and consequential decision: which of its cell lineages will make up the mortal body, and which will become the germline, the lineage that eventually makes eggs or sperm and carries genetic information to the next generation.

30 Jul 2026

Ten-million-person study links semaglutide to lower COVID-19 mortality

Researchers analyzing claims from more than 10.1 million commercial insurance and Medicare Advantage enrollees found that semaglutide use was associated with a 49% lower adjusted hazard of COVID-19-related death. The observational findings corroborate earlier SELECT trial results but do not establish causation, making further prospective research essential.

30 Jul 2026

Biotherapeutic metabolite repairs gut damage caused by HIV infection

Researchers at the UC Davis School of Medicine have identified a naturally occurring metabolite that repairs gut damage caused by HIV infection and significantly improves the effectiveness of antiretroviral therapy (ART) in the nonhuman primate model of HIV/AIDS.

30 Jul 2026

Microbial metabolites could help improve functional cure rates for hepatitis B

Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure (sustained HBsAg loss).

30 Jul 2026

Dual immunotherapy with neoadjuvant chemotherapy shows encouraging activity in ERBB2-negative breast cancer

A combination of two immunotherapy drugs showed encouraging activity when added to standard chemotherapy given prior to surgery for patients with high-risk, early-stage HER2-negative breast cancer, according to phase 2 clinical trial results from the ongoing I-SPY2 clinical trial platform.

30 Jul 2026

Immature NK cells in donor cord blood can undermine CAR NK cell therapy activity

The composition of donor cord blood may play a critical role in the success of chimeric antigen receptor (CAR) natural killer (NK) cell therapies.

29 Jul 2026

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.

28 Jul 2026

Researchers identify key barrier preventing self repair of heart cells

Specialized cells in our body make biological tradeoffs to do certain jobs. To support large and hardworking hearts that power our other organs, our heart cells evolved to be extremely efficient and resilient.

28 Jul 2026

Study reveals how gum disease drives systemic inflammation

A recent study revealed that periodontitis reprograms bone marrow neutrophils through a Chac2-driven glutathione metabolic pathway, promoting a highly inflammatory N1 state that fuels systemic inflammation.

28 Jul 2026

Blocking the Axl receptor may offer a new way to promote bone formation

Osteoporosis is one of the most common age-related bone diseases, affecting millions of people worldwide and increasing the risk of fractures, disability, and reduced quality of life.

28 Jul 2026

Landmark study identifies new genetic risk factors linked to fibromyalgia syndrome

In a landmark study published in Nature Medicine, an international team of researchers has identified new genetic risk factors associated with fibromyalgia syndrome.

28 Jul 2026

Blocking autophagy in blood vessels reduces skin inflammation in mice

Researchers at VIB and KU Leuven, together with international collaborators, have discovered that blocking autophagy - the body's natural recycling system for worn-out cell components - in specialized blood vessels can reduce inflammation in mice with psoriasis.

28 Jul 2026

Some caffeinated drinks are linked to poorer memory

A study on caffeine's impact reveals product-specific effects on anxiety, memory, and stress among university students, highlighting mental health implications.

28 Jul 2026

Too little or too much iodine may push immunity off balance

This narrative review finds that adequate iodine supports thyroid hormone signaling, leukocyte metabolism, antioxidant defenses, and antimicrobial activity in humans and domesticated mammals. Both deficiency and sustained excess may impair immunity or promote thyroid inflammation, but precise immune-specific intake thresholds remain uncertain.

27 Jul 2026

A common dietary nutrient feeds a gut pathway linked to atrial fibrillation

Researchers linked higher plasma TMAO to prevalent atrial fibrillation in 5,090 people and found that TMAO or choline supplementation accelerated AF onset, progression, atrial remodeling, and electrical dysfunction in mice. Inhibiting gut microbial TMA production lowered circulating TMAO and delayed AF in mice, identifying a potential therapeutic pathway that now requires human testing.

27 Jul 2026

St. Jude scientists uncover regulatory mechanism for crucial developmental pathway

St. Jude Children's Research Hospital scientists uncovered a regulatory mechanism for signaling of Sonic Hedgehog (SHH), a pathway essential for embryonic development.

27 Jul 2026

Dengue virus infects memory B cells to evade immune defenses

Researchers at the University of Vermont Robert Larner, M.D. College of Medicine and Upstate Medical University in Syracuse, NY, have discovered that dengue virus can infect and replicate inside memory B cells, immune cells traditionally understood to help protect the body from infection.

27 Jul 2026

Novogene Europe expands single-cell sequencing capability at Cambridge Omics Centre

Novogene Europe, a multiomics research services partner, today announced that it has expanded its single-cell RNA sequencing capability at its Cambridge Omics Centre.

From Novogene Europe 27 Jul 2026

Receptor News and Research

Immune cell navigation breakthrough offers hope for better anti-inflammatory drugs

Soy lysolecithin reduces salt-induced hypertension and cognitive decline

New research explains how embryos establish germline cell boundaries

Ten-million-person study links semaglutide to lower COVID-19 mortality

Biotherapeutic metabolite repairs gut damage caused by HIV infection

Microbial metabolites could help improve functional cure rates for hepatitis B

Dual immunotherapy with neoadjuvant chemotherapy shows encouraging activity in ERBB2-negative breast cancer

Immature NK cells in donor cord blood can undermine CAR NK cell therapy activity

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Researchers identify key barrier preventing self repair of heart cells

Study reveals how gum disease drives systemic inflammation

Blocking the Axl receptor may offer a new way to promote bone formation

Landmark study identifies new genetic risk factors linked to fibromyalgia syndrome

Blocking autophagy in blood vessels reduces skin inflammation in mice

Some caffeinated drinks are linked to poorer memory

Too little or too much iodine may push immunity off balance

A common dietary nutrient feeds a gut pathway linked to atrial fibrillation

St. Jude scientists uncover regulatory mechanism for crucial developmental pathway

Dengue virus infects memory B cells to evade immune defenses

Novogene Europe expands single-cell sequencing capability at Cambridge Omics Centre

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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