Renal disease News and Research

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Dartmouth researchers receive grant to study acute kidney injury

Over two million people in the United States undergo cardiac catheterization each year. While the procedure is used effectively for both diagnostic and interventional purposes, it is not without risk: Acute kidney injury (AKI) occurs in up to 14 percent of all patients following a cardiac catheterization and up to 50 percent in patients with pre-existing kidney disease.

11 Oct 2018

Experts call for more transparency about joint-venture ownership of dialysis clinics

Penn Medicine experts in nephrology and health policy call for more transparency about joint-venture ownership of dialysis clinics to better understand what impact these arrangements may have on patient referrals and clinical outcomes.

4 Oct 2018

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

AstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular outcomes trial for FARXIGA, the broadest SGLT-2 inhibitor CVOT conducted to date.

24 Sep 2018

People with acute critical illness have increased risk of kidney complications and death

Acute critical illness in people without previous renal disease puts them at risk of kidney complications as well as death, according to a study in published in CMAJ

10 Sep 2018

Biologic, environmental factors may be possible culprits for racial disparities in CKD progression

Although black and Hispanic veterans with chronic kidney disease are more likely than white patients to see a kidney specialist- a nephrologist- they are more likely to suffer disease progression from early stage to advanced kidney disease, reports a study published this month in the Journal of the American Society of Nephrology from researchers at the Perelman School of Medicine at the University of Pennsylvania.

24 Aug 2018

Kidney transplant chains save more lives than kidney exchanges, shows research

New research from the UBC Sauder School of the Business has found that transplant societies which prioritize kidney transplant chains over kidney exchanges can increase the total number of transplants, thereby saving more lives.

10 Aug 2018

Otsuka’s JINARC approved for treatment of patients with CKD stage 4 ADPKD

Otsuka Pharmaceutical Europe Ltd. today announced that the European Commission has approved an extension of indication for JINARC to include adult patients with CKD stage 4 Autosomal Dominant Polycystic Kidney Disease

2 Aug 2018

Captozyme begins cross-over study of Nephure oxalate reducing enzyme

Captozyme, Inc. announced today that it is initiating a prospective double-blind, randomized, placebo controlled, cross-over study, with Nephure, an oxalate reducing enzyme, to determine the extent to which Nephure vs. placebo reduces urinary oxalate excretion (mg/24 hour) in healthy subjects who are provided a controlled diet.

12 Jul 2018

Scoring system based on PIRO helps predict mortality in surgical ICU patients with severe sepsis

A new classification system that scores the variables associated with mortality rates for patients who develop intra-abdominal sepsis after surgery may help guide care and improve outcomes

2 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.

2 Jul 2018

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

New study examines living kidney donors' concerns on kidney removal

In a new study that examined living kidney donors' concerns about their decision to undergo kidney removal, long-term kidney health, aspects of surgery and recovery, and impacts on life satisfaction were among those that donors felt were most important.

1 Jun 2018

Another cause of doctor burnout: Being forced to give immigrants unequal care

One patient’s death changed the course of Dr. Lilia Cervantes’ career. The patient, Cervantes said, was a woman from Mexico with kidney failure who repeatedly visited the emergency room for more than three years. In that time, her heart had stopped more than once, and her ribs were fractured from CPR.

31 May 2018

Scientists reveal mechanisms that may help preterm infants extend nephron development window

Nephrons are the microscopic blood-filtering units inside our kidneys that convert waste products into urine, regulate our electrolyte levels and our blood pressure.

22 May 2018

Comprehensive care physician model reduces hospitalization and expense for high risk patients

Patients who need frequent hospitalization account for a disproportionate amount of health care spending in the United States.

17 May 2018

Study shows effectiveness of novel risk tool to predict readmission rates after TAVR

A new study looked at the effectiveness of novel risk tool to predict 30-day readmission rates in patients undergoing transcatheter aortic valve replacement.

27 Apr 2018

Data-driven tool defines risk stages for children with chronic kidney disease

Experts in pediatric kidney disease have published a new staging system to help doctors better predict the length of time until a child with chronic kidney disease (CKD) will need to undergo a kidney transplant or start receiving dialysis. Although this type of prognostic guide exists for adults, this is the first such tool specific to children.

10 Apr 2018

Trained navigators may improve patients' chances of receiving life-saving kidney transplants

In a recent study, a trained navigator who provided guidance to disadvantaged patients with kidney failure helped increase access to the transplant waitlist among patients who needed a longer time to get through the transplant evaluation process.

27 Mar 2018

Many patients show CKD signs prior to diabetes diagnosis

Many patients who will later be diagnosed with diabetes show signs of chronic kidney disease (CKD) even before their diabetes diagnosis, according to a study by researchers with the University of Tennessee Health Science Center and VA MidSouth Healthcare Network.

14 Mar 2018

New method may help improve patients' chances of receiving life-saving kidney transplants

A new method may be useful for assessing dialysis facilities' performance concerning referrals to transplant centers.

27 Jan 2018