Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

Minimally invasive technique for fixing bunions does not make flatfoot worse, study shows

Existing thought in the orthopedic world is that treating a bunion with the minimally invasive procedure MISB may make a person's flatfoot worse.

13 Mar 2023

UB researchers develop new tool to assess the presence and severity of sarcopenia

Sarcopenia is a degenerative disease characterized by a pathological decrease in muscle strength that particularly affects older people.

13 Mar 2023

The 2022 NICE guidelines for the diagnosis and management of gout

The 2022 National Institute for Health and Care Excellence (NICE) guidelines for the management of gout.

13 Mar 2023

C-reactive protein has a beneficial function in systemic lupus erythematosus

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory disease.

9 Mar 2023

Does treatment status relate to other diseases in gout patients?

A new study shows how urate-lowering therapy (ULT) is related to such conditions as chronic kidney disease (CKD) and cardiovascular disease (CVD).

8 Mar 2023

Intraoperative 3D imaging more effective in confirming the accuracy of pedicle screw placement during spine surgery

A study at Hospital for Special Surgery found that intraoperative three-dimensional (3D) imaging was superior to two-dimensional radiographs in confirming the accuracy of pedicle screw placement during spine surgery.

7 Mar 2023

Study reveals a connection between arthritis flare-ups and periodontitis

Regular visits to the dentist might help keep joint pain at bay, too.

6 Mar 2023

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

In a recent study published in Cells, researchers evaluated idiopathic pulmonary fibrosis (IPF) pathophysiological differences by sex and intestinal microbiome.

1 Mar 2023

Immunosuppressive drug methotrexate linked to increased risk of three types of skin cancer

The immunosuppressive drug methotrexate (MTX) can be linked to an elevated risk of three types of skin cancer, a new study by University of Gothenburg researchers shows.

7 Feb 2023

Some antidepressants may be effective in treating chronic pain, but others lack effectiveness

New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness.

1 Feb 2023

Targeting T cell iron metabolism may offer a new approach for treating lupus

Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) - the most common form of the chronic autoimmune disease lupus.

13 Jan 2023

COVID-19 outcomes in Rituximab treated patients

A new report throws light on SARS-CoV-2 breakthrough infections in patients with certain joint diseases or musculoskeletal conditions who are on rituximab and compares the severity of COVID-19 outcomes in these patients whilst identifying potential risk factors for severe outcomes.

11 Jan 2023

2022: a year in MIS-C research

In a recent review published in Nature Reviews Rheumatology, researchers reviewed existing data on the multisystem inflammatory syndrome in children (or MIS-C).

11 Jan 2023

Research suggests people on rheumatoid arthritis drugs show weaker response to SARS-CoV-2 vaccines

Researchers conducted a comparative study among a cohort of individuals on rheumatoid arthritis (RA) therapies vis-à-vis healthy controls to assess their responses to coronavirus disease 2019 (COVID-19) vaccines.

9 Jan 2023

All patients with rheumatic disorders recommended to receive pneumococcal vaccine

Patients with rheumatoid arthritis, lupus, and other rheumatic conditions are more at risk for complications and death from pneumonia, meningitis, and other bacterial infections, yet most have not been vaccinated against infection.

29 Dec 2022

Study could pave the way for new drug to treat hand osteoarthritis

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

22 Dec 2022

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

The Lupus Research Alliance (LRA) proudly announces the two outstanding recipients of the 2022 Distinguished Innovator Award (DIA): Hongbo Chi, PhD, and Joseph Craft, MD.

16 Dec 2022

Study finds a novel therapeutic target for prevention and treatment of gout

Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin and Thomas Jefferson.

14 Dec 2022

Research extends the powerful tool of immunotherapy to autoimmune diseases

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

6 Dec 2022

Rheumatology News and Research

Further Reading

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

Minimally invasive technique for fixing bunions does not make flatfoot worse, study shows

UB researchers develop new tool to assess the presence and severity of sarcopenia

The 2022 NICE guidelines for the diagnosis and management of gout

C-reactive protein has a beneficial function in systemic lupus erythematosus

Does treatment status relate to other diseases in gout patients?

Intraoperative 3D imaging more effective in confirming the accuracy of pedicle screw placement during spine surgery

Study reveals a connection between arthritis flare-ups and periodontitis

Study reveals synergistic impact of estrogen and intestinal dysbiosis on pulmonary fibrosis

Immunosuppressive drug methotrexate linked to increased risk of three types of skin cancer

Some antidepressants may be effective in treating chronic pain, but others lack effectiveness

Targeting T cell iron metabolism may offer a new approach for treating lupus

COVID-19 outcomes in Rituximab treated patients

2022: a year in MIS-C research

Research suggests people on rheumatoid arthritis drugs show weaker response to SARS-CoV-2 vaccines

All patients with rheumatic disorders recommended to receive pneumococcal vaccine

Study could pave the way for new drug to treat hand osteoarthritis

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

Study finds a novel therapeutic target for prevention and treatment of gout

Research extends the powerful tool of immunotherapy to autoimmune diseases

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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