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New technology maps molecules within single cells to uncover disease mechanisms

Tissues consist of a heterogenous mixture of different cell types, complicating our understanding of their biological functions and studies of disease.

14 May 2025

New glycopeptide antibiotic discovered to combat resistant bacteria

An international team of researchers, led by the University of Vienna and the Helmholtz Institute for Pharmaceutical Research Saarland, has discovered saarvienin A, a new type of glycopeptide antibiotic.

14 May 2025

New immunotherapy target found in pancreatic cancer cells

Researchers from MIT and Dana-Farber Cancer Institute have discovered that a class of peptides expressed in pancreatic cancer cells could be a promising target for T-cell therapies and other approaches that attack pancreatic tumors.

8 May 2025

New workflow enhances detection of low-abundant glycoproteins in blood plasma

A recent study published in Engineering presents a novel approach to analyzing the low-abundant N-glycoproteome in human blood plasma (HBP), which could significantly advance the discovery of plasma biomarkers.

8 May 2025

Scientists build world's most accessible gut bacteria collection to unlock health and disease clues

Researchers have developed the Human Intestinal Bacteria Collection (HiBC), comprising 340 gut bacterial strains from 198 species, including 29 newly described taxa, made publicly available for functional microbiome research.

7 May 2025

Innovative technology instantly spots street drugs

A portable device that can instantly detect dangerous street drugs at extremely low concentrations has been developed at the University of Bath in the UK.

7 May 2025

How urine caffeine levels may help detect diabetic eye damage early

Researchers found that higher urinary levels of caffeine and specific metabolites, especially in men, were significantly associated with diabetic retinopathy risk. The cross-sectional study used NHANES 2009–2014 data and highlights potential biomarkers for early detection in diabetic populations.

7 May 2025

Advancing benzodiazepine detection for toxicology

Learn how experts are advancing benzodiazepine analysis and detection using insights from the lab.

From Waters Advanced Diagnostics 5 May 2025

Leveraging the Radian ASAP in standard casework

Explore how the Radian ASAP mass spectrometer is being used to streamline and enhance seized drug screening.

From Waters Advanced Diagnostics 30 Apr 2025

Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

A journey through science, software, and innovation: Insights from the Bruker software team

Follow Bruker's experts as they discuss the SCRUM approach to software development in the scientific industry.

From Bruker Daltonics 29 Apr 2025

Carotid artery plaque contains elevated micronanoplastics

People with plaque in the blood vessels of their neck have a higher amount of tiny plastic particles in those vessels compared to people with healthy arteries.

22 Apr 2025

New expansion technique brings mass spectrometry imaging to single cell level

For biologists, seeing is believing. But sometimes biologists have a hard time seeing.

22 Apr 2025

Plastic additives found in 85% of foods raise concern for infant health

Researchers assessed plasticizer levels in foods typical of the Spanish diet and found widespread contamination, with infants showing the highest exposure. Certain additives, like DEHP, exceeded safety thresholds in high-exposure scenarios.

21 Apr 2025

Magnolia essential oil fights bacteria and oxidative stress with natural potency

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17 Apr 2025

Toxins in kids’ mattresses and bedding raise health concerns, study shows

A Canadian in-home study found that young children are significantly exposed to semi-volatile organic compounds (SVOCs) in their sleeping environments. Mattresses, bedding, and bedroom furnishings were identified as key sources, with several compounds exceeding expected levels.

17 Apr 2025

New method detects and quantifies nanoplastics in transparent body fluids

Microplastics and the much smaller nanoplastics enter the human body in various ways, for example through food or the air we breathe.

14 Apr 2025

Epigenetic discovery offers hope for reducing addiction relapse

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and thereby the formation of strong drug-related memories, which can trigger relapse in individuals with substance use disorders (SUDs).

10 Apr 2025

A new blood test could improve how Alzheimer’s disease is diagnosed

The blood test for eMTBR-tau243 shows strong correlation with tau pathology, enhancing Alzheimer's diagnosis and monitoring cognitive decline effectively.

1 Apr 2025

Blood test offers insight into Alzheimer's stage and severity

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.

31 Mar 2025