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Study reports the world's first genetically engineered pig-to-human liver xenotransplantation

An important new study in the Journal of Hepatology, published by Elsevier, reports the world's first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient.

9 Oct 2025

Identifying Alport syndrome in children through universal age-3 urine screening

The most common first diagnosis of Alport syndrome in Japan is during the universal age-3 urine screening.

7 Oct 2025

DKMS advances blood cancer research with groundbreaking ASAP study

The selection of patients for allo-HSCT and the best approach to bridging patients to transplantation is continuously discussed by experts.

6 Oct 2025

Enzyme technology enables first successful blood type conversion in kidney transplant

The first successful human transplant of a kidney converted from blood type A to universal type O used special enzymes developed at the University of British Columbia to help prevent a mismatch and rejection of the organ.

3 Oct 2025

Categorizing the risk factors for portal vein thrombosis in liver cirrhosis

Portal vein thrombosis (PVT) is a critical complication in liver cirrhosis (LC), significantly worsening portal hypertension and accelerating the progression to decompensation.

30 Sep 2025

Simple blood analysis can predict the risk of developing severe liver disease

A new study from Karolinska Institutet, published in the scientific journal The BMJ, shows how a simple blood analysis can predict the risk of developing severe liver disease.

29 Sep 2025

Stem cell treatment could help millions of people with end-stage kidney disease

More than 4 million people worldwide have end-stage kidney disease that requires hemodialysis, a treatment in which a machine filters waste from the blood.

24 Sep 2025

New research brings safer artificial hearts closer to clinical use

Using magnetic cameras, researchers at Linköping University have examined blood flow in an artificial heart in real time. The results make it possible to design the heart in a way to reduce the risk of blood clots and red blood cells breakdown, a common problem in today's artificial hearts.

24 Sep 2025

UCLA researchers identify proteins that guard the liver against damage during transplantation

In a mouse model of liver transplantation, UCLA researchers have identified proteins that act as "protective switches" guarding the liver against damage occurring when blood supply is restored during transplantation, a process known as ischemia-reperfusion injury.

23 Sep 2025

Gut microbial imbalance linked to chronic sickle cell disease pain

A research collaboration involving scientists and students at The University of Texas at Dallas has found a clear connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract.

22 Sep 2025

Study reveals early nicotinamide use reduces risk of aggressive skin cancers

A large U.S. Department of Veterans Affairs cohort study found that Nicotinamide use was associated with a 14% lower risk of new keratinocyte skin cancers, driven by a 22% reduction in cSCC and no reduction in BCC. The strongest benefit (56% lower risk) appeared when nicotinamide was started after a patient’s first skin cancer, with diminishing returns after multiple cancers.

18 Sep 2025

Breakthrough in building functional synthetic kidneys using assembloids

A USC Stem Cell-led research team has achieved a major step forward in the effort to build mouse and human synthetic kidneys.

17 Sep 2025

Lymphatic vessels found to undergo dramatic changes during kidney transplant rejection

Scientists have uncovered how lymphatic vessels – the kidney's 'plumbing system' – undergo dramatic changes during chronic transplant rejection, becoming structurally disorganised and spreading to unusual parts of the kidney.

16 Sep 2025

Stem cell therapy shows promise for repairing brain damage after stroke

When someone has a stroke - a leading worldwide cause of death and disability - time is of the essence. Almost nine out of 10 cases are ischemic strokes, caused by restricted blood flow in the brain, and the current gold-standard treatment that breaks up blood clots must be delivered within four and a half hours of symptoms appearing.

16 Sep 2025

Cleveland Clinic study shows lasting benefits of weight-loss surgery over GLP-1 medicines

A large Cleveland Clinic study has found that people with obesity and type 2 diabetes who undergo weight-loss surgery live longer and face fewer serious health problems compared with those treated with GLP-1 receptor agonist medicines alone.

16 Sep 2025

AI can predict which patients need treatment to preserve their eyesight

Researchers have successfully used artificial intelligence (AI) to predict which patients need treatment to stabilize their corneas and preserve their eyesight, in a study presented today (Sunday) at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS).

15 Sep 2025

UCLA team develops engineered antibodies to fight cytomegalovirus infection

A UCLA research team has found a new way to prompt the immune system to kill cells infected with cytomegalovirus (CMV), a life-threatening infection that is particularly deadly in immunocompromised people.

13 Sep 2025

A surgical team was about to harvest this man’s organs — until his doctor intervened

Lying on top of an operating room table with his chest exposed, Larry Black Jr. was moments away from having his organs harvested when a doctor ran breathlessly into the room.

12 Sep 2025

Persistent COVID-19 in the intestines may drive inflammation in cancer patients

New research from the University of Minnesota Medical School is providing important insights into how COVID-19 persists in cancer patients even long after testing positive. The findings were recently published in iScience.

10 Sep 2025

Researchers reveal why no level of air pollution is safe for respiratory health

A review in the Journal of Clinical Investigation shows how particulate matter damages the lungs through oxidative stress, inflammation, and immune disruption. It links air pollution to asthma, COPD, lung cancer, infections, and millions of premature deaths, with no safe exposure threshold.

9 Sep 2025