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Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Cirrhosis associated with lower immune responses to COVID-19 vaccines in patients with chronic liver disease

The overall responsiveness of patients with chronic liver disease (CLD) to COVID-19 vaccines has been shown to be decreased in patients with cirrhosis.

2 Mar 2023

Alarming Projection: By 2035, more than half of the global population will be obese

The World Obesity Atlas predicts that over 51% of the world population will be considered obese by 2035.

2 Mar 2023

Studying gut bacteria's role in muscle regeneration and recover

In a surprising discovery, Harvard Medical School researchers have found that a class of regulatory T cells (Tregs) made in the gut play a role in repairing injured muscles and mending damaged livers.

2 Mar 2023

Adding evidence to the weight gain causality of sugary drinks

The review, published in the American Journal of Clinical Nutrition, is the most extensive analysis to date of research on sweetened drinks and overweight and obesity - both of which heighten risks for diabetes, heart disease, some cancers, and other diseases.

2 Mar 2023

Gut bacteria influence the liver's regenerative ability

When parts of the liver are removed, the body can replace the missing tissue. A team of researchers at the Technical University of Munich has now discovered that the success of this process depends to a large extent on gut bacteria.

1 Mar 2023

Promising alternative strategy for islet transplantation in people with type 1 diabetes

In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets.

1 Mar 2023

Just 75 weekly minutes of physical activity can reduce the risks of early death and disease

One in 10 early deaths could have been prevented if everyone had met just half the recommended weekly target of 150 minutes of moderate intensity physical activity, indicates the largest pooled data analysis of its kind, published online in the British Journal of Sports Medicine.

1 Mar 2023

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

In a recent study posted to the Preprints with The Lancet SSRN* server, a team of researchers in China developed a machine learning-based diagnostic tool to detect tuberculosis and drug-resistant tuberculosis using nanoparticle-enhanced laser desorption/ionization mass spectrometry (NPELDI MS) to determine metabolic fingerprints from serum samples.

28 Feb 2023

Mercy Medical Center and UMMC offer a Liver Transplant Clinic to help transplant patients

The Center for Liver and Hepatobiliary Diseases at Mercy in conjunction with the University of Maryland Medical Center offers a Liver Transplant Clinic to help patients through the liver transplant process.

28 Feb 2023

St. Jude researchers show how drug makers can avoid toxicity and resistance

Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance.

28 Feb 2023

Digital twins can lead to more personalized drug therapies for inflammatory diseases

Inflammatory diseases like rheumatoid arthritis have complex disease mechanisms that can differ from patient to patient with the same diagnosis.

28 Feb 2023

Weight loss in obese subjects could reverse type 2 diabetes progression

A new paper explains a model of diabetes that centers on the role of obesity in glucose dysregulation.

28 Feb 2023

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the commercial launch of the PhysioMimix™ Single-organ Higher Throughput (HT) System.

From CN Bio 28 Feb 2023

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

A team of international scientists has recently characterized the structure of tumor necrosis factor receptor associated factor 6 (TRAF6) N-terminal domain for therapeutic purposes.

28 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

Liver News and Research

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Cirrhosis associated with lower immune responses to COVID-19 vaccines in patients with chronic liver disease

Alarming Projection: By 2035, more than half of the global population will be obese

Studying gut bacteria's role in muscle regeneration and recover

Adding evidence to the weight gain causality of sugary drinks

Gut bacteria influence the liver's regenerative ability

Promising alternative strategy for islet transplantation in people with type 1 diabetes

Just 75 weekly minutes of physical activity can reduce the risks of early death and disease

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

Mercy Medical Center and UMMC offer a Liver Transplant Clinic to help transplant patients

St. Jude researchers show how drug makers can avoid toxicity and resistance

Digital twins can lead to more personalized drug therapies for inflammatory diseases

Weight loss in obese subjects could reverse type 2 diabetes progression

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

What is the effect of maternal circulating amino acids on offspring birthweight?

High throughput device isolates and classifies metabolically active CTCs

Study shows the beneficial effect of verapamil in children with newly-diagnosed type 1 diabetes

Exploring biodistribution of cannabidiol nanoparticles and nanoemulsion after intrathecal administration

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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