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Combination of anti-cancer nanodrugs with Intralipid enhances therapeutic efficacy

Pairing chemotherapy nanodrugs with a nutritional supplement can lessen devastating side-effects while reducing the amount of the expensive drugs needed to treat cancer according to a study from Carnegie Mellon University and Taiwan's National Health Research Institutes.

10 Mar 2020

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

In the 2020 February 25 issue of Scientific Reports, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that levels of a circulating soluble immune checkpoint protein can be used as a potential marker to predict overall survival in patients with advanced HCC.

9 Mar 2020

New device to measure brain pH with increased spatial and temporal accuracy

Although a number of techniques are able to track changes in pH in the brain, precise measurements have not previously been possible. Now, however, researchers in Japan have developed a novel method for examining brain pH that may lead to new information about the role of pH in brain signaling.

7 Mar 2020

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Harvard University's Wyss Institute of Biologically Inspired Engineering and its collaborating institutions, the Harvard John A. Paulson School of Engineering and Applied Sciences, Dana-Farber Cancer Institute, and Harvard's Department of Stem Cell and Regenerative Biology, announce the formation of a new NIH-funded Immuno-Engineering to Improve Immunotherapy Center.

7 Mar 2020

Molecule-sized drills can target diseased cells and kill them in minutes

Molecule-sized drills do the damage they are designed to do. That's bad news for disease.

5 Mar 2020

Fatty nutrients control certain neurons in the reward circuit

Energy-dense food, obesity and compulsive food intake bordering addiction: the scientific literature has been pointing to connections between these for years.

5 Mar 2020

New tool shows potential to predict developmental toxicity in humans with high accuracy

Recently published results from an evaluation of 1,065 chemical and drug substances using the devTOX quickPredict (devTOXqP) screening platform developed by Stemina Biomarker Discovery, Inc. demonstrated the platform's ability to predict developmental toxicity in humans with high accuracy using a cell-based test.

3 Mar 2020

Metrohm USA announces 8th annual Young Chemist Award winner

Metrohm USA is pleased to announce the winner of its 2020 Young Chemist Award, Dr.

From Metrohm USA Inc. 3 Mar 2020

Manipulation of CRF neurons motivates behavioral style selection under stress

In response to stressors, individuals exhibit different coping styles, each characterized by a set of behavioral, physiological, and psychological responses.

2 Mar 2020

Gene therapy regenerates functional new neurons in mouse models of HD

Huntington's disease (HD) is a rare disease characterized by abnormal chorea movement and caused by Huntingtin (Htt) gene mutation and neurodegeneration in a brain area called striatum.

28 Feb 2020

Scientists reveal ability to reverse Huntington's disease-causing DNA repeat mutations in the lab

Neurodegenerative diseases, like Huntington's disease and myotonic dystrophy, are often referred to as DNA repeat diseases, named because of long repeated sequences in the DNA of patients. Increasing repeat expansion length in the affected tissues contribute to earlier age of disease onset and worsen the progression and severity of the disease over time.

27 Feb 2020

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

APEIRON Biologics AG, a biotechnology company with an approved product on the market as well as a broad preclinical and clinical pipeline, today announced the launch of a Pilot investigator-initiated clinical trial with APN01, a recombinant human angiotensin-converting enzyme 2, to treat patients with severe coronavirus infection in the People's Republic of China.

26 Feb 2020

Coronavirus vaccine trials commence

The coronavirus disease (COVID-19) outbreak has swept the world, killing 2,770 people and infecting more than 81,000. Amid the health crisis, scientists from across the globe are racing to develop novel therapies and vaccines in the hope of stemming the spread of the deadly virus.

26 Feb 2020

New form of gene editing slows ALS progression in mice

With a new CRISPR gene-editing methodology, scientists from the University of Illinois at Urbana-Champaign inactivated one of the genes responsible for an inherited form of amyotrophic lateral sclerosis - a debilitating and fatal neurological disease for which there is no cure.

26 Feb 2020

Stem cell discovery could open the door to new approach for bone marrow transplantation

Mount Sinai researchers have discovered a way to enhance the potency of blood-forming stem cells, potentially opening the door to a new approach for bone marrow transplantation, according to a study being published on February 27 in Cell Stem Cell.

26 Feb 2020

MILabs achieves breakthrough in preclinical oncology imaging by eliminating positron range blurring effect

Researchers at MILabs B.V. have succeeded at imaging the popular Zirconium-89 isotope in small animals of human disease at very high resolutions (<0.75 mm).

19 Feb 2020

Study uses MRI to probe non-invasively inside a living brain

The wiring network of the brain is made up of billions of nerve fibers called axons. The thickness of axons - together with other properties - significantly impacts the way in which they conduct neural signals, and therefore the overall processing speed of connected neurons and brain areas.

18 Feb 2020

New 3D model shows how breast cancer cells interact with the body’s stem cells

A Loughborough University Ph.D. student has provided new insight into how breast cancer cells interact with cells in our body by using a novel 3D model.

18 Feb 2020

Scientists develop new tool using machine learning to diagnose lymphedema

Scientists at the TSU Laboratory for Biophotonics, with specialists from the Tomsk Scientific Research Institute of Microsurgery, have developed a new tool for diagnosing lymphedema, a severe pathology that can develop after radical treatment of several oncological diseases.

17 Feb 2020

Microscopy in Neuroscience Research

An interview with ZEISS, to discuss the challenges faced in neuroscience research microscopy techniques and their latest microscope.

From ZEISS Microscopy GmbH 17 Feb 2020

in vivo News and Research

Combination of anti-cancer nanodrugs with Intralipid enhances therapeutic efficacy

Levels of sBTLA proteins may be a marker of overall survival in patients with HCC

New device to measure brain pH with increased spatial and temporal accuracy

New 'Immuno-Engineering to Improve Immunotherapy' Center formed to advance cancer therapy

Molecule-sized drills can target diseased cells and kill them in minutes

Fatty nutrients control certain neurons in the reward circuit

New tool shows potential to predict developmental toxicity in humans with high accuracy

Metrohm USA announces 8th annual Young Chemist Award winner

Manipulation of CRF neurons motivates behavioral style selection under stress

Gene therapy regenerates functional new neurons in mouse models of HD

Scientists reveal ability to reverse Huntington's disease-causing DNA repeat mutations in the lab

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

Coronavirus vaccine trials commence

New form of gene editing slows ALS progression in mice

Stem cell discovery could open the door to new approach for bone marrow transplantation

MILabs achieves breakthrough in preclinical oncology imaging by eliminating positron range blurring effect

Study uses MRI to probe non-invasively inside a living brain

New 3D model shows how breast cancer cells interact with the body’s stem cells

Scientists develop new tool using machine learning to diagnose lymphedema

Microscopy in Neuroscience Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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