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Women taking immunosuppressive medications during pregnancy do not put their babies at risk

Women with chronic autoimmune diseases who take immunosuppressive medications during their first trimester of pregnancy are not putting their babies at significantly increased risk of adverse outcomes, according to a Vanderbilt study released online by the journal Arthritis and Rheumatism.

11 Nov 2013

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

A team of scientists that includes Saint Louis University researchers has identified a new way to intervene in the molecular and cellular cascade that causes fibrosis - a condition where the body's natural process of forming scars for wound healing goes into overdrive and causes diseases.

11 Nov 2013

Drug used to treat intestinal worms could protect people from periodontitis, says study

A drug currently used to treat intestinal worms could protect people from periodontitis, an advanced gum disease, which untreated can erode the structures-including bone-that hold the teeth in the jaw. The research was published ahead of print in Antimicrobial Agents and Chemotherapy.

11 Nov 2013

TGen-led study reveals viable target to prevent spread of brain cancer

A cellular pathway interaction known as TWEAK-Fn14, often associated with repair of acute injuries, also is a viable target for drug therapy that could prevent the spread of cancer, especially brain cancer, according to a study led by the Translational Genomics Research Institute.

11 Nov 2013

Study examines effectiveness of minimally invasive endoscopic procedure for removing esophagus

Use of a minimally invasive endoscopic procedure to remove superficial, early stage esophageal cancer is as effective as surgery that takes out and rebuilds the esophagus, according to a study by researchers at Mayo Clinic in Florida. The research, published in Clinical Gastroenterology and Hepatology, examined national outcomes from endoscopic treatment compared to esophagectomy, surgical removal of the esophagus.

8 Nov 2013

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

An innovative Northwestern Medicine- research program investigating if stem cells may be the key to allowing organ transplant patients to stop taking immunosuppressive drugs has received $12 million in research funding. The grant will allow researchers to finish Phase II of the clinical trials and begin Phase III.

8 Nov 2013

Report: Postmastectomy pain rated as most troubling symptom by breast cancer survivors

More than 40 percent of 200,000 U.S. women diagnosed with breast cancer every year undergo surgery. Though treatment advances have significantly reduced mortality from breast cancer, a study published in The Journal of Pain reported that persistent postmastectomy pain is rated by survivors as their most troubling symptom. The Journal of Pain is published by the American Pain Society, www.americanpainsociety.org.

8 Nov 2013

BioCryst Pharmaceuticals initiates BCX4161 Phase 2a trial in HAE patients

BioCryst Pharmaceuticals, Inc. today announced that it has dosed the first subject in OPuS-1 (Oral ProphylaxiS-1), a Phase 2a proof of concept clinical trial of orally-administered BCX4161 in patients with hereditary angioedema.

8 Nov 2013

Amneal to launch AB-rated generic for Loestrin 24 Fe

Amneal Pharmaceuticals LLC will launch its AB-rated generic for Loestrin 24 Fe (norethindrone acetate and ethinyl estradiol tablets, USP and ferrous fumarate tablets) 1 mg/20 mcg, 75 mg the first week of January 2014.

8 Nov 2013

Four-year study to develop targeted approach to psoriasis treatment

A world-leading taskforce led by The University of Manchester has begun work to create a new test to help medics work out which treatment plan is most likely to improve the disabling skin condition psoriasis, based on a patient's individual biological make-up.

8 Nov 2013

Cancer pioneer James Allison wins 2013 Innovations Award for bioscience

For basic science research that opened a completely new approach for treating cancer, The Economist has named James Allison, Ph.D., professor and chair of Immunology at The University of Texas MD Anderson Cancer Center, as its 2013 Innovations Award winner in Bioscience.

8 Nov 2013

Findings raise prospects for new therapies to protect heart from progressive disease

Some of the most commonly prescribed drugs for the treatment of heart failure are beta-blockers and nitrates, which help to relax blood vessels and decrease the heart's workload. The drugs were thought to produce those effects through distinct molecular pathways, but according to a new study led by scientists at Temple University School of Medicine, both types of drugs may help the failing heart by counteracting the effects of an enzyme known as GRK2.

8 Nov 2013

Cholesterol metabolite promotes tumor growth in breast cancers

A team of researchers at UT Southwestern has found that as cholesterol is metabolized, a potent stimulant of breast cancer is created - one that fuels estrogen-receptor positive breast cancers, and that may also defeat a common treatment strategy for those cancers.

8 Nov 2013

Oral allergy syndrome sufferers with hypertension may be at increased risk for severe reaction

Oral allergy syndrome sufferers that take high blood pressure medications may experience extreme facial swelling and difficulty breathing the next time they bite into a juicy apple.

8 Nov 2013

$Risedronate may help prevent new vertebral fractures when taken with calcium and vitamin D$

Risedronate may help prevent new vertebral fractures when taken with calcium and vitamin D

A recent prospective, randomized, placebo-controlled clinical trial reports that calcium and vitamin D supplementation improves bone density in a group of male veterans with epilepsy who were treated chronically with antiepileptic drugs.

8 Nov 2013

Nanoparticles with chemotherapeutic drugs can kill drug-resistant breast cancer cells

Nanoparticles filled with chemotherapeutic drugs can kill drug-resistant breast cancer cells, according to a study published in the scientific journal Biomaterials.

8 Nov 2013

Primary care patients with anxiety disorders receive potentially adequate medication

A new study by Brown University psychiatry researchers found that seven in 10 primary care patients with anxiety disorders eventually received potentially adequate medication or psychotherapy, but for many it took years to happen and it was considerably less likely for minorities.

8 Nov 2013

Vitamin C can improve skeletal muscle fatigue in COPD patients

Chronic obstructive pulmonary disease—a health problem in which the lungs lose their inherent springiness, making it progressively harder to breathe—can have a dramatic effect on the ability to exercise and even perform simple activities of daily life because of the disease's fallout effects on skeletal muscles.

8 Nov 2013

Vitamin D and calcium improves bone density in male veterans treated with AEDs

8 Nov 2013

Topera receives FDA clearance for FIRMap Catheter

Topera, Inc., a medical device company that has developed a novel mapping and targeting system for the identification of the sources that sustain complex cardiac arrhythmias, today announced that it has received 510(k) clearance by the U.S. Food and Drug Administration for the FIRMap Catheter.

7 Nov 2013

Therapy News and Research

Women taking immunosuppressive medications during pregnancy do not put their babies at risk

Findings demonstrate potential new therapeutic approach to treat fibrotic diseases

Drug used to treat intestinal worms could protect people from periodontitis, says study

TGen-led study reveals viable target to prevent spread of brain cancer

Study examines effectiveness of minimally invasive endoscopic procedure for removing esophagus

Northwestern Medicine receives $12 million to continue organ transplant research with stem cells

Report: Postmastectomy pain rated as most troubling symptom by breast cancer survivors

BioCryst Pharmaceuticals initiates BCX4161 Phase 2a trial in HAE patients

Amneal to launch AB-rated generic for Loestrin 24 Fe

Four-year study to develop targeted approach to psoriasis treatment

Cancer pioneer James Allison wins 2013 Innovations Award for bioscience

Findings raise prospects for new therapies to protect heart from progressive disease

Cholesterol metabolite promotes tumor growth in breast cancers

Oral allergy syndrome sufferers with hypertension may be at increased risk for severe reaction

Risedronate may help prevent new vertebral fractures when taken with calcium and vitamin D

Nanoparticles with chemotherapeutic drugs can kill drug-resistant breast cancer cells

Primary care patients with anxiety disorders receive potentially adequate medication

Vitamin C can improve skeletal muscle fatigue in COPD patients

Vitamin D and calcium improves bone density in male veterans treated with AEDs

Topera receives FDA clearance for FIRMap Catheter

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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