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Donor stem cell transplant can improve survival rates for older patients with MDS, study shows

A new clinical trial offers the most compelling evidence to date that a donor stem cell transplant can improve survival rates for older patients with higher-risk myelodysplastic syndrome (MDS), Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology Annual Meeting.

5 Dec 2020

Matrix-induced autologous chondrocyte implantation shows comparable benefit to therapy alternatives

Autologous chondrocyte implantation (ACI) has been used in adults with deep cartilage defects for over 30 years and has been further developed and modified over time.

5 Dec 2020

Research aids in the development of synthetic materials to mimic bone

University of Arkansas researchers Marco Fielder and Arun Nair have conducted the first study of the combined nanoscale effects of water and mineral content on the deformation mechanisms and thermal properties of collagen, the essence of bone material.

5 Dec 2020

Study shows how minerals come together at molecular level to form bones, hard tissues

A new paper in Science Advances describes for the first time how minerals come together at the molecular level to form bones and other hard tissues, like teeth and enamel.

4 Dec 2020

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD).

2 Dec 2020

Indiana University researchers report a specific type of childhood cancer

Researchers at Indiana University School of Medicine have published their work about a specific type of childhood cancer in the peer-reviewed, international oncology journal, Cancers.

2 Dec 2020

More than 40 Dana-Farber studies to be presented at the virtual 62nd ASH Annual Meeting

Dana-Farber Cancer Institute researchers will present more than 40 research studies at the virtual 62nd American Society of Hematology Annual Meeting on December 5-8, including two studies that were selected for inclusion in the official press program.

1 Dec 2020

First PSMA-targeted PET imaging drug approved for men with prostate cancer

Today, the U.S. Food and Drug Administration approved Gallium 68 PSMA-11 (Ga 68 PSMA-11) - the first drug for positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA) positive lesions in men with prostate cancer.

1 Dec 2020

$Obesity linked with risk of early hip fracture in postmenopausal women$

Obesity linked with risk of early hip fracture in postmenopausal women

Obese women have an increased risk of hip fracture earlier than others, already well before the age of 70, a new study from the University of Eastern Finland shows. The study followed 12,715 women for a period of 25 years. The new findings from the Osteoporosis Risk Factor and Prevention (OSTPRE) study were published in Osteoporosis International.

1 Dec 2020

Gut microbiota directly shapes the makeup of human immune system, shows study

MSK researchers have uncovered an important finding about the relationship between the microbiota and the immune system, showing for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Researchers reveal link between gut bacteria and vitamin D levels

Our gut microbiomes -- the many bacteria, viruses and other microbes living in our digestive tracts -- play important roles in our health and risk for disease in ways that are only beginning to be recognized.

30 Nov 2020