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Novel platform can become a potential approach for personalized cancer treatments

Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and cancer cells.

22 Feb 2022

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Researchers compared the secondary attack rates SARS-CoV-2 Omicron and Delta variants of concern in Norwegian households.

22 Feb 2022

Assessing the transmissibility of SARS-CoV-2 variants of concern

A new study investigated and compared the transmissibility of severe acute respiratory syndrome coronavirus-2 variants of concern.

22 Feb 2022

SARS CoV-2 in deer from Pennsylvania sampled during fall and winter 2021

Researchers examined whether SARS-CoV-2-infected white-tailed deer could be the new animal reservoir with the potential to spillback new SARS-CoV-2 variants into humans.

22 Feb 2022

An abundance of SARS-CoV-2-like viruses in hunted wild animals traded in China

New research published in the journal Cell assesses the viromes of 18 different species of game animals across China to predict potential pathogens similar to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could infect human populations.

22 Feb 2022

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

In a recent study published in the journal PLoS ONE, researchers investigated the effect of genetic variability based on accessory gene deletions on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and the clinical severity of coronavirus disease 2019 (COVID-19).

22 Feb 2022

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

In a recent study published in the journal PLoS ONE, researchers evaluated the temporal spread and geographic distribution of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) genomic variants.

21 Feb 2022

Monitoring rise of SARS-CoV-2 variants in wastewater using genome sequencing

Researchers conduct genomic wastewater surveillance of SARS-CoV-2 following the emergence of the Alpha and Delta variants in the United Kingdom.

21 Feb 2022

The logic that controls gene regulation in human cells discovered

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge can be applied to, for example, investigating cancers and other genetic diseases.

21 Feb 2022

Comparative transmission study of SARS-CoV-2 Omicron and Delta variant in England

Researchers performed an epidemiological cohort study to assess differences in transmission of the SARS-CoV-2 Omicron and Delta variants in England.

21 Feb 2022

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

A new review paper published in PLoS Pathogens discusses the new variants and the structural mechanism underlying antibody-mediated neutralization as well as mutational antibody escape.

21 Feb 2022

Comparing the genomic landscapes of SARS-CoV-2 isolated from animal species relative to that in humans

A recent study identified six candidate mutations in the SARS-CoV-2 genome adaptive to animal hosts.

21 Feb 2022

The relative contagiousness of the Alpha, Delta, and Omicron SARS-CoV-2 variants

A new study, available on the arXiv* server, proposes a simple dynamic model for estimating the relative contagiousness of two variants of SARS-CoV-2, namely Alpha and Delta. Furthermore, it demonstrates how to compute the effective reproduction number for a new variant without contemporaneous sequencing results. This is important to assess the state of the pandemic in real-time.

20 Feb 2022

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

A new study focuses on understanding the factors associated with the ability of the Omicron variant to infect a wide range of age groups.

20 Feb 2022

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

The research showed a highly attenuated SARS-CoV-2 strain that might be used as a live-attenuated vaccine platform and a BSL-2 experimental system.

18 Feb 2022

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

The SARS-CoV-2 virus is continuously evolving and structural changes to the virus may impact the efficacy of antibody therapies and vaccines.

18 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

New insights could help long-term care facilities enhance infection prevention and control measures

Findings from a study published today in the American Journal of Infection Control provide new insights that could help long-term care facilities assess the cleanliness of high-touch surfaces, and thereby enhance infection prevention and control measures designed to prevent serious diarrheal diseases and deaths among their residents.

17 Feb 2022

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

Researchers assess how fast the SARS-CoV-2 Alpha and Delta variants transmit from transmission data in a household study.

17 Feb 2022

New open-source software tool could accelerate genetic discoveries

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation should accelerate their development - as well as genetic editing advances overall.

17 Feb 2022

Genomic News and Research

Novel platform can become a potential approach for personalized cancer treatments

SARS-CoV-2 Omicron variant rapidly takes over Delta viral strain in Norwegian households

Assessing the transmissibility of SARS-CoV-2 variants of concern

SARS CoV-2 in deer from Pennsylvania sampled during fall and winter 2021

An abundance of SARS-CoV-2-like viruses in hunted wild animals traded in China

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

Global SARS-CoV-2 genetic sequence distribution in early COVID-19

Monitoring rise of SARS-CoV-2 variants in wastewater using genome sequencing

The logic that controls gene regulation in human cells discovered

Comparative transmission study of SARS-CoV-2 Omicron and Delta variant in England

Molecular characteristics of SARS-CoV-2 variants enabling antibody escape

Comparing the genomic landscapes of SARS-CoV-2 isolated from animal species relative to that in humans

The relative contagiousness of the Alpha, Delta, and Omicron SARS-CoV-2 variants

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

Study reveals the structural, functional landscape of neutralizing antibodies against SARS-CoV-2 spike protein

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

New insights could help long-term care facilities enhance infection prevention and control measures

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

New open-source software tool could accelerate genetic discoveries

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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