Therapy News and Research

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Hydroxyurea treatment prevents complications, lowers medical care costs in children sickle cell disease

The benefits of hydroxyurea treatment in people with sickle cell disease are well known -- fewer painful episodes, fewer blood transfusions and fewer hospitalizations. Now new research from the Johns Hopkins Children's Center and other institutions reveals that by preventing such complications, the drug can also considerably lower the overall cost of medical care in children with this condition.

12 Sep 2013

Levels of certain fats in cerebral spinal fluid can predict patients with HIV, say scientists

Johns Hopkins scientists have found that levels of certain fats found in cerebral spinal fluid can predict which patients with HIV are more likely to become intellectually impaired.

12 Sep 2013

CPT-F antibiotic drug may hold promise for treating potentially fatal MRSA pneumonia

A drug approved just two years ago for treating bacterial infections may hold promise for treating the potentially fatal MRSA pneumonia, according to a Henry Ford Hospital study.

12 Sep 2013

FDA grants Breakthrough Therapy designation to Syndax's entinostat for ER+ breast cancer

Syndax Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has designated entinostat as a Breakthrough Therapy for the treatment of locally recurrent or metastatic estrogen receptor-positive (ER+) breast cancer when added to exemestane in postmenopausal women whose disease has progressed following non-steroidal aromatase inhibitor therapy.

12 Sep 2013

Professors receive 100,000 Euro from Hartwig Piepenbrock-DZNE for outstanding brain research

The prize is awarded by the Piepenbrock Group and the German Center for Neurodegenerative Diseases (DZNE). The award ceremony will be held in Berlin on September 24, 2013.

12 Sep 2013

Alert to CAM use in asthma

Researchers from Canada say that physicians should be aware of the high prevalence of complementary and alternative medicine use among patients with asthma.

11 Sep 2013

Astrazeneca Licenses Merck's Cancer Candidate MK-1775

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11 Sep 2013

MicroBiome Therapeutics' NM504 eliminates diarrhea caused by metformin in type 2 diabetes patient

MicroBiome Therapeutics LLC, a biotechnology company developing pharmaceutical and medical food products that shift the human microbiome in specific ways for improved health, today reported publication of a case report suggesting a potentially important new application for its lead product, NM504. NM504 is in clinical development to promote healthy blood glucose levels and metabolic fitness in prediabetic and diabetic populations.

11 Sep 2013

Improved lung function in patients with moderate asthma severity observed with investigational Tiotropium

Boehringer Ingelheim will present a pooled analysis of new data from the Phase 3 UniTinA-asthma® program at the European Respiratory Society (ERS) Annual Congress 2013 in Barcelona. The data from the individual MezzoTinA-asthma® Phase 3 studies (NCT01340209 and NCT00565266), from which the pooled data are derived, show the addition of tiotropium delivered via the Respimat® inhaler to medium-dose maintenance inhaled corticosteroid (ICS) therapy (defined as 400-800 µg budesonide/day or equivalent) improved lung function and provided sustained bronchodilation over 24 hours in patients with moderate asthma and airflow limitation. Tiotropium is being investigated to determine the medicine’s efficacy in treating asthma patients and is not currently approved for this indication.

11 Sep 2013

Strides therapeutic approach helps autistic children reach breakthroughs in communication

Luke, a 7-year-old autistic child had primarily only expressed requests to his parents (e.g., I want a drink), but this past year he was given a 1-pound iPad, introduced to a 1,000 pound horse and a special program called Strides©.

11 Sep 2013

State highlights: Texas Gov. Perry touts tort reform; Calif. lawmakers want to pass 100 bills per day

A measles outbreak in a vaccination-wary North Texas megachurch and soaring rates of whooping cough across the state are drawing renewed calls for immunization legislation, which some lawmakers and medical professionals argue would help the state prevent public health crises (Aaronson, 9/10).

11 Sep 2013

Rutgers scientist finds important clue on origins of multiple sclerosis

The search for the cause of multiple sclerosis, a debilitating disease that affects up to a half million people in the United States, has confounded researchers and medical professionals for generations. But Steven Schutzer, a physician and scientist at Rutgers New Jersey Medical School, has now found an important clue why progress has been slow - it appears that most research on the origins of MS has focused on the wrong part of the brain.

11 Sep 2013

Combination drug does not improve survival in patients with severe alcoholic hepatitis

Four weeks of treatment with a combination of the drug pentoxifylline and the corticosteroid prednisolone did not improve 6-month survival compared with prednisolone alone in 270 patients with severe alcoholic hepatitis, according to a study in the September 11 issue of JAMA.

11 Sep 2013

Personalized treatment may be effective in wild type cancers

As a woman in her mid-forties who didn't smoke, Elizabeth Lacasia never expected to be diagnosed with lung cancer. But in 2006, after she developed a persistent and serious cough, a chest X-ray and CT scan revealed several tumors in her lower left lung.

11 Sep 2013

Research finding could lead to better solutions for cancer, anti-viral treatments

Medical scientists at the University of Alberta have made a key discovery about how the immune system kills healthy cells while attacking infections. This finding could one day lead to better solutions for cancer and anti-viral treatments.

11 Sep 2013

New bill allows Californians to directly access physical therapist services

California's Senate passed AB 1000 (Wieckowski/Maienschein) to allow Californians to directly access physical therapist services. The bill passed off the Senate Floor and now goes back to the Assembly to approve amendments before heading to the Governor's desk.

11 Sep 2013

Researchers discover 4 novel gene variations linked with blood pressure

Case Western Reserve University is part of a landmark study that has discovered four novel gene variations associated with blood pressure. The 19-site meta-analysis, involving nearly 30,000 African-Americans, also found that the set of genetic mutations are also associated with blood pressure across other populations.

11 Sep 2013

New strategy to reduce central line-associated bloodstream infections

Simply replacing the connector in the IV system in patients with central lines could help reduce deadly bloodstream infections, researchers at Georgia Regents University have found.

11 Sep 2013

Discovery opens doors for developing new therapies to eradicate tumor cells, combat infections

Scientists from A*STAR's Singapore Immunology Network have discovered a new defense mechanism that the immune system utilises to combat infections. The team's discovery of how a novel protein unexpectedly activates an immune response shows how this mechanism can also be used to get rid of tumour cells.

11 Sep 2013

Astrazeneca, Hadasit Launch Drug Discovery Alliance

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10 Sep 2013

Therapy News and Research

Hydroxyurea treatment prevents complications, lowers medical care costs in children sickle cell disease

Levels of certain fats in cerebral spinal fluid can predict patients with HIV, say scientists

CPT-F antibiotic drug may hold promise for treating potentially fatal MRSA pneumonia

FDA grants Breakthrough Therapy designation to Syndax's entinostat for ER+ breast cancer

Professors receive 100,000 Euro from Hartwig Piepenbrock-DZNE for outstanding brain research

Alert to CAM use in asthma

Astrazeneca Licenses Merck's Cancer Candidate MK-1775

MicroBiome Therapeutics' NM504 eliminates diarrhea caused by metformin in type 2 diabetes patient

Improved lung function in patients with moderate asthma severity observed with investigational Tiotropium

Strides therapeutic approach helps autistic children reach breakthroughs in communication

State highlights: Texas Gov. Perry touts tort reform; Calif. lawmakers want to pass 100 bills per day

Rutgers scientist finds important clue on origins of multiple sclerosis

Combination drug does not improve survival in patients with severe alcoholic hepatitis

Personalized treatment may be effective in wild type cancers

Research finding could lead to better solutions for cancer, anti-viral treatments

New bill allows Californians to directly access physical therapist services

Researchers discover 4 novel gene variations linked with blood pressure

New strategy to reduce central line-associated bloodstream infections

Discovery opens doors for developing new therapies to eradicate tumor cells, combat infections

Astrazeneca, Hadasit Launch Drug Discovery Alliance

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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