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MJFF awards $1.35M to Rhythm for Phase 2 clinical trial of RM-131 for Parkinson's disease

Rhythm announced today that The Michael J. Fox Foundation for Parkinson's Research has awarded a $1.35 million research grant to Rhythm to help fund a Phase 2 clinical trial of RM-131, the company's novel ghrelin agonist, for the treatment of refractory constipation in patients with Parkinson's disease.

10 Sep 2013

Boehringer Ingelheim completes patient enrolment for interferon-free hepatitis C treatment

Boehringer Ingelheim today announced the completion of patient enrolment for a Phase IIa clinical trial investigating a new interferon-free, all-oral, direct-acting antiviral combination treatment for patients with genotype-1a chronic hepatitis C virus infection.

10 Sep 2013

Hospira announces EC approval of Inflectra, Europe's first biosimilar mAb therapy

Hospira, the world's leading provider of injectable drugs and infusion technologies, today announced the European Commission (EC) approval of Inflectra™ (infliximab), Europe's first biosimilar monoclonal antibody (mAb) therapy. Inflectra has been approved for the treatment of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis, Crohn's disease (CD), ulcerative colitis (UC), psoriatic arthritis (PsA) and psoriasis.

10 Sep 2013

Metamark reports positive results from clinical validation study of prostate cancer prognostic test

Metamark Genetics, Inc., a privately-held biotechnology company, today announced positive results from a large clinical validation study of ProMark, its biopsy-based prostate cancer prognostic test.

10 Sep 2013

Researchers assess prevalence, cost of critical care therapies seen as futile by doctors

In one of the first studies of its kind, a joint UCLA/RAND Corporation study addressed the prevalence and cost of critical care therapies provided in intensive care units that were perceived by physicians as "futile."

10 Sep 2013

GIQuIC expands endoscopic quality registry to include upper GI endoscopy

The GI Quality Improvement Consortium announces the expansion of its endoscopic quality registry to include upper GI endoscopy and related quality measures. GIQuIC, a quality benchmarking registry co-sponsored by the American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy, provides reliable and relevant measures of endoscopic quality that give physicians meaningful information they can use to improve patient care.

10 Sep 2013

Combination of 2 antiviral drugs improves outcome in monkey model of MERS-CoV infection

National Institutes of Health (NIH) scientists report that a combination of two licensed antiviral drugs reduces virus replication and improves clinical outcome in a recently developed monkey model of Middle East respiratory syndrome coronavirus (MERS-CoV) infection.

10 Sep 2013

Novel viral therapy to treat specific types of cancer in children

Parents do everything they can to protect their children against all of the nasty germs floating around classrooms across the country this time of year. Doctors and researchers at Nationwide Children's Hospital, however, are looking into how those same types of common viruses can actually help treat a child who is diagnosed with certain cancers.

10 Sep 2013

Biologists identify two pathways via which chromosomes are rearranged

Biologists reported today in Nature that they have identified two pathways through which chromosomes are rearranged in mammalian cells. These types of changes are associated with some cancers and inherited disorders in people.

10 Sep 2013

Most patients who report statin intolerance can actually tolerate drugs on subsequent trials

Most patients who report statin intolerance, including muscle aches and other side effects from the cholesterol-lowering drugs, can actually tolerate drugs from this class on subsequent trials, according to research from Cleveland Clinic recently released online and forthcoming in the September issue of the American Heart Journal. The study is the largest ever to examine the effects of re-challenging statin-intolerant patients.

10 Sep 2013

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

A little STING could go a long way in helping treat or even avoid autoimmune diseases such as arthritis, type 1 diabetes and multiple sclerosis, researchers report.

10 Sep 2013

Focusing on mental health key to improving physical health in teens: Study

Adding a mental health component to school-based lifestyle programs for teens could be key to lowering obesity, improving grades, alleviating severe depression and reducing substance use, a new study suggests.

10 Sep 2013

One-time treatment slows onset and progression of ALS, study finds

Studies of a therapy designed to treat amyotrophic lateral sclerosis suggest that the treatment dramatically slows onset and progression of the deadly disease, one of the most common neuromuscular disorders in the world.

10 Sep 2013

Researchers discover why multiple myeloma persistently escapes cure

Clinical researchers at Princess Margaret Cancer Centre have discovered why multiple myeloma, an incurable cancer of the bone marrow, persistently escapes cure by an initially effective treatment that can keep the disease at bay for up to several years.

10 Sep 2013

Brown, University of Cape Town partner to create next generation of HIV social science in South Africa

The public health schools at Brown University and the University of Cape Town have launched a new research and training partnership to create "the next generation of HIV social science in South Africa." The Eunice Kennedy Shriver National Institute of Child Health and Human Development is funding the collaboration with a new $1.9 million, five-year grant.

10 Sep 2013

Researchers identify genetic link specific to risk of childhood leukemia

For the first time, a genetic link specific to risk of childhood leukemia has been identified, according to a team of researchers from Memorial Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, University of Washington, and other institutions. The discovery was reported online today in the journal Nature Genetics.

10 Sep 2013

Ferritin protects kidneys against damage by controlling iron

A protein, ferritin, protects kidneys against a damaging after-effect of injury, heart failure or hardened arteries by controlling levels of iron, according to a study published today by researchers at the University of Alabama at Birmingham in the Journal of Clinical Investigation.

10 Sep 2013

Combined transplantation provides potential new therapy for repair of spinal cord injury

Following spinal cord injury, astrocyte proliferation and scar formation are the main factors inhibiting the regeneration and growth of spinal cord axons, leading to motor and sensory function loss below the level of spinal cord injury.

10 Sep 2013

Identifying changes in handwriting could lead to early diagnosis of Parkinson's

Today's primary tool for diagnosing Parkinson's disease is the diagnostic ability of the physician, who can generally identify the clinical symptoms only when the disease is at a relatively advanced stage. A new joint study by researchers at the University of Haifa and Rambam Hospital that compared the handwriting of 40 sick and healthy subjects suggests an innovative and noninvasive method of diagnosing Parkinson's at a fairly early stage.

10 Sep 2013

European launch of new version of REVIVE™ SE Thrombectomy Device for treatment of acute ischemic stroke announced by Codman Neuro

Codman Neuro*, part of DePuy Synthes Companies of Johnson & Johnson, announced the European launch of the REVIVE™ SE Thrombectomy Device, a next generation clot removal device offering enhanced navigation through the cerebral vasculature and rapid restoration of blood flow to the brain after an ischemic stroke.

9 Sep 2013

Therapy News and Research

MJFF awards $1.35M to Rhythm for Phase 2 clinical trial of RM-131 for Parkinson's disease

Boehringer Ingelheim completes patient enrolment for interferon-free hepatitis C treatment

Hospira announces EC approval of Inflectra, Europe's first biosimilar mAb therapy

Metamark reports positive results from clinical validation study of prostate cancer prognostic test

Researchers assess prevalence, cost of critical care therapies seen as futile by doctors

GIQuIC expands endoscopic quality registry to include upper GI endoscopy

Combination of 2 antiviral drugs improves outcome in monkey model of MERS-CoV infection

Novel viral therapy to treat specific types of cancer in children

Biologists identify two pathways via which chromosomes are rearranged

Most patients who report statin intolerance can actually tolerate drugs on subsequent trials

Little STING could go long way in avoiding arthritis, type 1 diabetes, report researchers

Focusing on mental health key to improving physical health in teens: Study

One-time treatment slows onset and progression of ALS, study finds

Researchers discover why multiple myeloma persistently escapes cure

Brown, University of Cape Town partner to create next generation of HIV social science in South Africa

Researchers identify genetic link specific to risk of childhood leukemia

Ferritin protects kidneys against damage by controlling iron

Combined transplantation provides potential new therapy for repair of spinal cord injury

Identifying changes in handwriting could lead to early diagnosis of Parkinson's

European launch of new version of REVIVE™ SE Thrombectomy Device for treatment of acute ischemic stroke announced by Codman Neuro

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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