B Cell News and Research

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Study contradicts long-established dogma about eye immunity

A person needs immune-suppressive drugs for organ transplants but not typically for transplants in the eye. How come? Like a few other parts of the body, some components of the eye, like the lens, don't have direct access to vessels that deliver immune cells.

27 Jan 2018

Scientists decipher molecular mechanism of the cell with relevance for cancer development

Achievement in the field of cancer research: Biologists and chemists at the University of Konstanz decipher a molecular mechanism of the cell with relevance for the development of cancer and the fight against that disease.

27 Jan 2018

Global effort toward HIV cure published in Special Issue of AIDS Research and Human Retroviruses

Researchers have shown that despite effective combined antiretroviral therapy, HIV can hide in the spleen of patients with no detectable HIV in their blood.

27 Jan 2018

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Stem cell researchers at UConn Health have reversed Prader-Willi syndrome in brain cells growing in the lab, findings they recently published in the Human Molecular Genetics.

27 Jan 2018

Small tweak to mammal's DNA can cause significant physical changes, study finds

The difference between webbed toes and distinct digits may be the result of not just genetic information, but of how the genes regulate that information. Researchers at the National Institute of Genetics, Research Organization of Information and Systems in Japan found that a small, non-specific tweak to a mammal's DNA can potentially cause specific and significant physical changes.

27 Jan 2018

SUTD-NCL team completes phenotypic screening of MMV Malaria Box against pathogenic parasites

A Singapore-India collaborative research project between the Singapore University of Technology & Design and CSIR-National Chemical Laboratories completed phenotypic screening of a large collection of potent chemical inhibitors (known as MMV Malaria Box), against pathogenic parasites Toxoplasma gondii and Plasmodium falciparum, causative agents of human toxoplasmosis and malaria.

27 Jan 2018

Researchers uncover key protein that rescues progression of adult spinocerebellar ataxia

Spinocerebellar ataxia is a group of neurodegenerative diseases characterized by progressive incoordination of gait, and is often associated with poor coordination of hands, speech, and eye movements.

27 Jan 2018

Sugar-attaching enzyme found to be abundant in colon cancer cells

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry.

27 Jan 2018

Scientists identify role of Mesp1 gene in earliest step of cardiovascular lineage segregation

Researchers at the Université libre de Bruxelles and University of Cambridge identified the role of key gene Mesp1 in the earliest step of cardiovascular lineage segregation. This discovery may help to better understand congenital heart defects.

27 Jan 2018

Study reveals existence of previously unknown immune defense mechanisms in bacteria

Until a decade ago, scientists were not aware that bacteria had complex immune systems – ones that could keep up with the pace of evolution in viruses called phages that infect bacteria.

27 Jan 2018

Scientists use synthetic protein to disrupt bacteria’s ability to perform basic life functions

A synthetic protein that disrupts the ability of bacteria to perform basic life functions - moving, eating, attaching to hosts - could be a key to fighting infectious disease and preventing bacteria from evolving into drug-resistant pathogens.

27 Jan 2018

CureMatch’s co-founder is co-author of new article in Cancer Discovery journal

Igor F. Tsigelny, Ph.D., Co-founder and Chief Strategic Officer at CureMatch and research professor at University of California, San Diego, is a co-author of “Genomic landscape of cell-free DNA in patients with colorectal cancer” in Cancer Discovery along with group of colleagues from Duke University Medical Center, University of Texas MD Anderson Cancer Center, Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, Caris Life Sciences, and Guardant Health, Inc. organized by the Drs. Ryan B. Corcoran and Scott Kopetz.

27 Jan 2018

Biotechnology startup receives FDA clearance for synthetic bone graft substitute

A biotechnology startup enabled by UC Davis, Molecular Matrix Inc., has received Food and Drug Administration clearance for a carbohydrate-based polymer that can help injured bones heal and regrow.

27 Jan 2018

Scientists test new tactic for controlling motor complications in Parkinson's disease

Standard drug treatment for Parkinson's disease can over time induce motor complications that reduce the effectiveness of restoring mobility.

27 Jan 2018

Immune system handles graphene oxide in a way similar to pathogens, study shows

A study by researchers at Karolinska Institutet, the University of Manchester and Chalmers University of Technology published in CHEM shows that our immune system handles graphene oxide in a manner similar to pathogens, paving the way for safer biomedical applications of this two-dimensional material.

27 Jan 2018

Laser pointer exposure causes eye injuries

In recent years, a substantial increase in the number of eye injuries caused by laser pointers has been observed, especially in children and adolescents.

26 Jan 2018

Scientists discover promising new target to fight a class of viruses

Scientists at the Morgridge Institute for Research have discovered a promising new target to fight a class of viruses responsible for health threats such as Zika, polio, dengue, SARS and hepatitis C.

25 Jan 2018

Researchers identify promising new drug target for Ewing sarcoma

Screening a class of recently-developed drug compounds -- so-called "CDK inhibitors" capable of blocking CDK7/12/13 proteins -- against hundreds of different human cancer cell lines, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that CDK12 inhibitors pack a particularly lethal punch to Ewing sarcoma, a rare cancer typically affecting children and young adults.

25 Jan 2018

Biologists discover new genetic pathway for injured nerve regeneration

On the hunt for genes involved in regenerating critical nerve fibers called axons, biologists at the University of California San Diego came away with a surprise: The discovery of a new genetic pathway that carries hope for victims of traumatic injuries - from stroke to spinal cord damage.

25 Jan 2018

Research could explain link between high-cholesterol diet and increased colon cancer risk

New UCLA research could help explain the link between a high-cholesterol diet and an elevated risk for colon cancer.

25 Jan 2018

B Cell News and Research

Study contradicts long-established dogma about eye immunity

Scientists decipher molecular mechanism of the cell with relevance for cancer development

Global effort toward HIV cure published in Special Issue of AIDS Research and Human Retroviruses

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Small tweak to mammal's DNA can cause significant physical changes, study finds

SUTD-NCL team completes phenotypic screening of MMV Malaria Box against pathogenic parasites

Researchers uncover key protein that rescues progression of adult spinocerebellar ataxia

Sugar-attaching enzyme found to be abundant in colon cancer cells

Scientists identify role of Mesp1 gene in earliest step of cardiovascular lineage segregation

Study reveals existence of previously unknown immune defense mechanisms in bacteria

Scientists use synthetic protein to disrupt bacteria’s ability to perform basic life functions

CureMatch’s co-founder is co-author of new article in Cancer Discovery journal

Biotechnology startup receives FDA clearance for synthetic bone graft substitute

Scientists test new tactic for controlling motor complications in Parkinson's disease

Immune system handles graphene oxide in a way similar to pathogens, study shows

Laser pointer exposure causes eye injuries

Scientists discover promising new target to fight a class of viruses

Researchers identify promising new drug target for Ewing sarcoma

Biologists discover new genetic pathway for injured nerve regeneration

Research could explain link between high-cholesterol diet and increased colon cancer risk

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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