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Circadian clock proteins set the pace of plant growth

Scientists at the Centre for Research in Agricultural Genomics (CRAG) in Spain have identified the members of a protein family linked with the internal clocks of plants that act sequentially to restrict plant growth until just before daylight, according to a new study published in the journal Current Biology.

15 Jan 2018

Administration of two proteins shown to counteract neurodegeneration in Parkinson's disease

A combination therapy made up of two neurotrophic factors can reduce the degenerative effects of Parkinson’s disease, shows new research.

15 Jan 2018

Variations in bacterial strains can trigger varying immune responses, study states

A new study published in PLOS Pathogens revealed the role of genetic variations between different strains of the same bacterial species in inducing variations in immune system responses. Former studies have shown that susceptibility to infection with the same species of disease causing bacteria may vary among people.

15 Jan 2018

Synergy between two neurotrophic factors exerts beneficial effect in early phase of Parkinson’s disease

Parkinson's disease is currently the second most widespread neurogenerative pathology. Current therapies are mainly of a replacement type and pose problems in the long term, so the challenge is to establish an early diagnosis and develop neuroprotective and neurorestorative therapies that will allow the symptoms of the disease to be slowed down or even reversed.

12 Jan 2018

Past exposures influence immune response in children with acute respiratory tract infections

Acute respiratory tract infections (ARTI) are the leading global cause of death in early childhood, according to the Centers for Disease Control and Prevention.

12 Jan 2018

Stem cell transplant can effectively treat patients with rare autoimmune disease, study shows

An unusual autoimmune disease that causes skin and lung damage can be treated effectively by stem cell transplant, a new study in the New England Journal of Medicine has found.

12 Jan 2018

Researchers discover new warning system in the immune defense

Researchers at Linköping University in Sweden have discovered a previously unknown warning system that contributes to the body's immune system. Mitochondria in the white blood cells secrete a web of DNA fibers that raises the alarm.

12 Jan 2018

Scientists develop new technique to map electrical circuits in the brain

In a feat of nanoengineering, scientists have developed a new technique to map electrical circuits in the brain far more comprehensively than ever before.

12 Jan 2018

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

A discovery by scientists at Dana-Farber Cancer Institute and University of Texas Southwestern Medical Center presents drug developers with an entirely new tack in targeting one of the most-wanted molecular culprits in cancer.

12 Jan 2018

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.

12 Jan 2018

Prostate cancer’s gene-determined ‘immune landscape’ dictates tumor progression

The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumors result in distinct paths of disease progression and response to therapy.

12 Jan 2018

New drug candidates may offer breakthrough in treatment of COPD

The study was a cooperative effort between the team headed by assistant professor Dr Jürgen Knobloch from the Medical Clinic III for Pneumology, Sleep and Respiratory Medicine at the Bergmannsheil University Hospital in Bochum, Germany, and Prof Dr Andrea Koch, member of the German Center for Lung Research, previously in Bochum, now at the Medical Clinic V for Pneumology at the LMU University Hospital in Munich, as well as a team from the company RespiVert Ltd, a subsidiary of Janssen Biotech Inc., and Prof Dr Erich Stoelben from the Lung Clinic in Köln-Merheim.

12 Jan 2018

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

The human protein, prohibitin, may be used by the virus to enter motor neurons and cause the neurological complications of hand, foot and mouth disease.

12 Jan 2018

Progression and regression rates of cervical lesions depend on patient's race, study shows

Physicians determining treatment options following abnormal Pap smears now have another factor to consider: the patient's race.

12 Jan 2018

RAS dimers essential for causing cancer, study shows

Mutated RAS genes are some of the most common genetic drivers of cancer, especially in aggressive cancers like pancreatic and lung cancer, but no medicines that target RAS are available despite decades of effort.

12 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

B Cell News and Research

Circadian clock proteins set the pace of plant growth

Administration of two proteins shown to counteract neurodegeneration in Parkinson's disease

Variations in bacterial strains can trigger varying immune responses, study states

Synergy between two neurotrophic factors exerts beneficial effect in early phase of Parkinson’s disease

Past exposures influence immune response in children with acute respiratory tract infections

Stem cell transplant can effectively treat patients with rare autoimmune disease, study shows

Researchers discover new warning system in the immune defense

Scientists develop new technique to map electrical circuits in the brain

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Prostate cancer’s gene-determined ‘immune landscape’ dictates tumor progression

New drug candidates may offer breakthrough in treatment of COPD

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

Progression and regression rates of cervical lesions depend on patient's race, study shows

RAS dimers essential for causing cancer, study shows

Research provides insights into mechanisms governing healthy longevity

UCLA scientists coax human stem cells to become sensory interneurons

Novel antifungal shows promise to stave off drug-resistant superbugs

Researchers discover new weapon to combat tuberculosis

New study shows how the immune system regulates gut fungal population

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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