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Deciphering Antibodies with Next-Generation Protein Sequencing Technology

Mr. Mingjie Xie, MSc, MBA, is the co-founder and CEO of Rapid Novor Inc. He is a computer scientist by training andreceived his MSc degree from Western University in the field of bioinformatics. He received his MBA degree from Richard Ivey School of Business to pursue his interests in business. Prior to co-founding Rapid Novor Inc, Mingjie is the COO of a bioinformatics software company.

From Rapid Novor Inc 9 Jan 2018

Survival strategy of mRNAs during sugar deficiency in the cell

If a cell runs low on sugar, it stores certain messenger RNAs in order to prolong its life. As a research group at the Biozentrum of the University of Basel has now discovered, the protein Puf5p determines whether individual messenger RNAs will be stored or degraded when sugar levels are low.

9 Jan 2018

Oncologists discover cell type that gives rise to soft tissue cancer in children

St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children.

8 Jan 2018

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

Amity Manning, assistant professor of biology and biotechnology, has received a three-year, $300,000 award from the Smith Family Awards Program for Excellence in Biomedical Research.

8 Jan 2018

Scientists use artificial intelligence to create new ‘ImmunoMap’

Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells.

8 Jan 2018

Newly identified biomarkers predict cancer patient’s response to immunotherapy

Researchers at the University of Zurich have identified biomarkers in the blood that make it possible to predict whether cancer patients will respond positively to immunotherapy.

8 Jan 2018

Study finds a cellular mechanism that protects plant genes from impacts of mutation

According to a new study conducted at the University of Oxford, a cellular mechanism termed DNA mismatch repair (MMR), preferentially protects plant genes from the damaging impacts of mutation.

8 Jan 2018

New understanding of how molecules regulate enzyme could lead to potential cancer targets

New understandings of how molecules affect the activity of an enzyme could lead to potential targets for the treatment of cancers and neurodegenerative diseases.

5 Jan 2018

Bielefeld scientists discover cause of initially unclear symptoms

The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.

5 Jan 2018

Researchers pinpoint mechanism for conversion of white fat into brown fat

An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat.

5 Jan 2018

Radiation therapy algorithm could lessen side effects, maintain effectiveness of treatment

Researchers at North Carolina State University have developed a mathematical model for computing radiation therapy treatments that could substantially reduce patient side effects while delivering the same results as conventional radiation therapy.

5 Jan 2018

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Acute chest syndrome (ACS), a potentially severe lung complication of sickle cell disease, increases a child's risk of respiratory failure, chronic lung disease, and prolonged hospitalization if not recognized early and treated effectively.

5 Jan 2018

Study identifies how excess fat disrupts heart cells' ability to produce energy

A University of Iowa study has identified how excess fat in the heart, a common feature in diabetes and obesity, can harm the cells' essential ability to produce energy.

5 Jan 2018

Research reveals how Zika virus infection spurs fetal demise

A powerful antiviral protein may act as a checkpoint for keeping or ending a pregnancy.

5 Jan 2018

Safety tips to prevent carbon monoxide poisoning during winter

On January 4, 2018, a 13-year-old girl died and dozens of people were injured by carbon monoxide poisoning in Perth Amboy, NJ.

5 Jan 2018

HSS researchers win grant to determine if stem cell therapy can improve outcomes for rotator cuff tears

A multidisciplinary team led by Scott Rodeo, MD, and Christopher Mendias, PhD, at Hospital for Special Surgery has been awarded the Orthopaedic Research and Education Foundation Clinical Research Grant in Cellular Therapy in honor of James Urbaniak, MD in Collaboration with National Stem Cell Foundation.

5 Jan 2018

Stem cell transplant improves survival among scleroderma patients

Scleroderma with internal organ involvement is a debilitating and lethal autoimmune disorder with few effective treatments. But a study led by Duke Health researchers has found new cause for optimism using an aggressive stem cell transplant regimen.

5 Jan 2018

Newly described super-silenced DNA reveals novel approach to reprogram cells

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Cell last week by investigators from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2018

Adrenomedullin could serve as biomarker, therapeutic target in disorders caused by leaky blood vessels

Disorders caused by a leaky vasculature are more common than most people think. Despite ICU treatment, one third of the 27 million patients globally that suffer from sepsis, and up to 20% of the more than 5 million US patients with congestive heart failure die every year from their condition.

5 Jan 2018

Cellular mechanism protects genes from damaging effects of mutation

Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.

5 Jan 2018

B Cell News and Research

Deciphering Antibodies with Next-Generation Protein Sequencing Technology

Survival strategy of mRNAs during sugar deficiency in the cell

Oncologists discover cell type that gives rise to soft tissue cancer in children

WPI professor receives Smith Family Foundation grant to explore biology of cancer cells

Scientists use artificial intelligence to create new ‘ImmunoMap’

Newly identified biomarkers predict cancer patient’s response to immunotherapy

Study finds a cellular mechanism that protects plant genes from impacts of mutation

New understanding of how molecules regulate enzyme could lead to potential cancer targets

Bielefeld scientists discover cause of initially unclear symptoms

Researchers pinpoint mechanism for conversion of white fat into brown fat

Radiation therapy algorithm could lessen side effects, maintain effectiveness of treatment

Strategies to prevent and treat acute chest syndrome in children with sickle cell disease

Study identifies how excess fat disrupts heart cells' ability to produce energy

Research reveals how Zika virus infection spurs fetal demise

Safety tips to prevent carbon monoxide poisoning during winter

HSS researchers win grant to determine if stem cell therapy can improve outcomes for rotator cuff tears

Stem cell transplant improves survival among scleroderma patients

Newly described super-silenced DNA reveals novel approach to reprogram cells

Adrenomedullin could serve as biomarker, therapeutic target in disorders caused by leaky blood vessels

Cellular mechanism protects genes from damaging effects of mutation

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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