Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Scientists discover new approach for treating virus-induced lymphomas

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis.

19 Mar 2007

New drug target for herpes viruses

Scientists in the lab of Whitehead Institute Member Hidde Ploegh and the Harvard University lab of Rachelle Gaudet have solved the complex structure of a recently discovered protein that is found in a wide range of herpes viruses. This protein may prove to be a potential drug target.

11 Mar 2007

New drug target for herpes viruses

11 Mar 2007

Drug delivery system that consists of nanocrystals of a hydrophobic drug

The problem of efficiently delivering drugs, especially those that are hydrophobic or water-repellant, to tumors or other disease sites has long challenged scientists to develop innovative delivery systems that keep these drugs intact until reaching their targets.

8 Mar 2007

Digital network links cardiovascular research globally

With $8.5 million in federal support, leading researchers at three universities, including Johns Hopkins, are creating an ambitious digital network that will allow cardiovascular researchers worldwide to easily exchange data and expertise on heart-related illnesses.

6 Mar 2007

New terms for describing gene products involved in microbial-host interactions

An international group of scientists has announced a major expansion of a lingua franca used to describe the activities of genes in living organisms.

28 Feb 2007

DNA 'cages' to deliver drugs

By combining DNA macromolecules with polymers containing iron, molecular 'cages' can be made: porous structures capable of carrying and delivering drugs or DNA-fragments.

26 Feb 2007

microRNAs undergo molecular editing with significant physiological consequences

Tiny molecules called microRNAs, only 19 to 21 nucleotides in length, are able to effectively silence sometimes large sets of genes. They do this by specifically binding to and neutralizing another form of RNA called messenger RNA, responsible for conveying the information from genes to the cellular machinery that uses that information to create proteins, the building blocks of the body.

22 Feb 2007

Entire genetic blueprints of more than 2,000 human and avian influenza viruses completed and made public

The Influenza Genome Sequencing Project, funded by the National Institute of Allergy and Infectious Diseases (NIAID), announced today that it has achieved a major milestone.

21 Feb 2007

Four genes identified that increase risk of developing type 2 diabetes

This form of diabetes is the most common worldwide and affects nearly 2 million Canadians. In recent years, the prevalence of Type 2 diabetes has increased rapidly. This genetic discovery may help stem this rise.

19 Feb 2007

Loss of a universal tRNA feature

Scientists at the Virginia Bioinformatics Institute (VBI) report in the Journal of Bacteriology that two alphaproteobacteria lack the universal extra guanylate nucleotide typically found in the transfer RNA molecule tRNAHis.

7 Feb 2007

Chromatin plasticity gets a 3.7 Million Euro boost

The European Commission has awarded 3.7 Million Euro under the European Union Framework 6 Programme over the next four years to a new Marie Curie Research Training Network, coordinated by Dr. Andreas Ladurner at the European Molecular Biology Laboratory (EMBL).

24 Jan 2007

New dynamic view of protein dynamics

Scientists from the Institute for Research in Biomedicine (IRB Barcelona), the Life Sciences Programme at the Barcelona Supercomputing Center (BSC) and the National Institute for Bioinformatics (INB) have published a provisional "atlas" of the dynamic behaviour of proteins in the prestigious scientific journal, Proceedings of the National Academy of Sciences.

9 Jan 2007

BioMed Central launches BMC Systems Biology

BioMed Central has announced the launch of BMC Systems Biology, the first open access journal focussed solely on the entire emerging subject of systems biology.

8 Jan 2007

Discovery of mechanism by which Ebola and Marburg viruses cause disease

Researchers in the Greene Infectious Disease Laboratory at Columbia University's Mailman School of Public Health, the Centers for Disease Control and Prevention, and the Caribbean Primate Research Center have discovered a key mechanism by which the Filoviruses, Ebola and Marburg, cause disease.

16 Oct 2006

NIH to map genomic changes of lung, brain, and ovarian cancers

It is estimated that 174,470 new cases of lung cancer will be diagnosed in the United States in 2006. Lung cancer is the major cause of cancer-related mortality in both men and women, with an estimated 162,460 deaths expected to occur in 2006.

13 Sep 2006

Drug ads and their influence on patients and doctors

Television ads for prescription drugs are everywhere, enticing people to ask their doctors for this drug or that one, but the effect this type of ad has on American healthcare may be more complicated than simply inducing patients to choose one brand or the other, according to a team of researchers.

12 Sep 2006