Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Titanium nanoparticles found in coal smog and ash can cause lung damage in mice

Virginia Tech scientists have discovered that incredibly small particles of an unusual and highly toxic titanium oxide found in coal smog and ash can cause lung damage in mice after a single exposure, with long-term damage occurring in just six weeks.

5 Feb 2020

Targeting a protein could be key to suppressing breast cancer metastasis

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis.

5 Feb 2020

Magnetically levitated plasma proteins could vastly improve diagnosis of diseases

Researchers at Michigan State University's Precision Health Program have helped develop a fascinating new method for detecting the density of proteins in the blood - a method that could vastly improve the rate at which diseases are detected and diagnosed.

5 Feb 2020

Indivumed and Biognosys partnership aims to enhance proteomics insights

Indivumed, a physician-led, integrated global oncology solution provider, announced its partnership with Biognosys.

From Biognosys 4 Feb 2020

New way to classify pituitary tumors could lead to better diagnoses

Houston Methodist neurosurgeons and neuroscientists are looking at a new way to classify pituitary tumors that could lead to more precise and accurate diagnosing for patients in the future.

4 Feb 2020

Potential new biomarker for vascular dementia identified

Vascular dementia is caused by a defect on blood flow arrival to the brain, which consequently generates neuronal damage.

30 Jan 2020

Prescription drug bumetanide could help treat autism

A new drug called bumetanide, which is used to treat edema, shows promise in treating some symptoms of autism in young children, while not showing significant adverse effects. The study was published in January 2020 in the journal Translational Psychiatry.

26 Jan 2020

Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

Determining microsatellite instability status using multiplex PCR-based methods used to screen for Lynch Syndrome, a dominant hereditary cancer propensity.

From Promega Corporation 24 Jan 2020

Portable optical biosensor slashes sepsis diagnosis time

Sepsis claims one life every four seconds. It is the primary cause of death in hospitals, and one of the ten leading causes of death worldwide.

23 Jan 2020

Protein linked with neurodegenerative diseases may help explore the aggressive behavior of gliomas

A protein typically associated with neurodegenerative diseases like Alzheimer's might help scientists explore how gliomas, a type of cancerous brain tumor, become so aggressive.

22 Jan 2020

PET/MRI identifies potentially useful breast cancer biomarkers

Researchers have identified several potentially useful breast cancer biomarkers that indicate the presence and risk of malignancy, according to new research published in the January issue of The Journal of Nuclear Medicine.

22 Jan 2020

New wearable gas sensor may soon be available for environmental and health monitoring

A highly sensitive, wearable gas sensor for environmental and human health monitoring may soon become commercially available, according to researchers at Penn State and Northeastern University.

16 Jan 2020

New sensitive marker may enable early diagnosis, treatment of spotted fever rickettsioses

Rickettsiae are bacteria that cause severe, potentially lethal human infections, including Mediterranean spotted fever and Rocky Mountain spotted fever.

16 Jan 2020

'Methylation clock' gene found to have functional role in aging of the eye

A lengthy-named gene called Elongation of Very Long Chain Fatty Acids Protein 2 or ELOVL2 is an established biomarker of age.

16 Jan 2020

What the 2020s have in store for aging boomers

Within 10 years, all of the nation's 74 million baby boomers will be 65 or older. The most senior among them will be on the cusp of 85.

16 Jan 2020

B cell count tells how certain cancers will respond to immunotherapy

Some melanomas, sarcomas and renal cell carcinomas, but not all, have been found to respond dramatically to new drugs called immune checkpoint blockers, which exploit the body’s known capability to mount an immune response against the foreign antigen-bearing tumor cells.

15 Jan 2020

Unique tool to democratize entry into the field of nanopore research

A nanopore is a tiny hole in a thin membrane with a diameter of around a billionth of a meter, or about the width of a single DNA molecule.

14 Jan 2020

UT Southwestern researchers explain racial disparities in heart failure risk

Researchers at UT Southwestern have uncovered evidence that the higher prevalence of "malignant" enlargement of the heart among blacks contributes to the higher incidence of heart failure in this population.

14 Jan 2020

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Daltonics 14 Jan 2020

The circadian clock is key to reducing radiation‐induced cardiotoxicity

Treatment for breast cancer commonly includes radiation therapy, which offers good chances of success but comes with a serious long-term side effect: toxicity due to radiation that reaches the heart, causing DNA damage in healthy heart cells. Over time, this can lead to heart disease and eventually heart failure.

13 Jan 2020