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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

MIT researchers develop new technique for genome-wide studies of the liver

The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.

21 Nov 2022

The role of bacteria in cancer growth

Tumor-associated microbiota is an important component of the tumor microenvironment (TME) across 33 types of human cancer. However, little evidence is available regarding the spatial distribution and localization of these microbes in tumor cells.

20 Nov 2022

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

Bombali ebolavirus has been detected among bats in Mozambique

Researchers reported on the detection of Bombali virus (BOMV, of the ebolavirus genus) ribonucleic acid (RNA) among three free-tailed Mops condylurus (Molossidae) bat species in Mozambique.

18 Nov 2022

How gut microbes influence immune response to SARS-CoV-2

An article published in Critical Reviews in Food Science and Nutrition journal provides an overview of the role of gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

In a recent study posted to the bioRxiv* preprint server, researchers evaluated responses of natural killer (NK) lymphocytes to VACV (vaccinia virus) infections in vivo.

16 Nov 2022

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

The SARS-CoV-2 Deltacron does not exhibit higher transmissibility or immune evasion than the Omicron BA.1 variant.

16 Nov 2022

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports.

16 Nov 2022

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

Clostridioides difficile, often referred to as C. difficile or C. diff, is a bacterium that causes severe intestinal illness and, as its name suggests, can be difficult to study and treat.

16 Nov 2022

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Researchers at the National Institutes of Health have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD).

16 Nov 2022

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

Researchers from the Centenary Institute and the University of Sydney have developed a new nasal vaccination strategy that induces potent lung immunity and protection against the SARS-CoV-2 coronavirus.

16 Nov 2022

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King's College London and the University of Bath in the UK.

16 Nov 2022

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Lung cancer is the leading cause of cancer deaths globally and a top cause of cancer deaths in the Military Health System.

15 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

Research sheds light on cardiac pathology mechanisms of COVID-19

Researchers compared cardiac autopsy samples from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive cases with age-matched samples from influenza hemagglutinin 1 neuraminidase 1 (H1N1) cases, non-influenza lymphocytic myocarditis cases, and heart tissue with no inflammation to understand the mechanisms underlying the pathology of the cardiac complications during coronavirus disease 2019 (COVID-19).

15 Nov 2022

What are the current challenges and future directions of mRNA nanomedicine?

Researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations and future directions to improve the clinical efficacy of mRNA nanomedicine.

15 Nov 2022

RNA News and Research

Further Reading

MIT researchers develop new technique for genome-wide studies of the liver

The role of bacteria in cancer growth

Rutgers scientists develop new approach to effectively shut down viral infections

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

Bombali ebolavirus has been detected among bats in Mozambique

How gut microbes influence immune response to SARS-CoV-2

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

Antibiotic-resistant, opportunistic pathogen enhances the pathogenesis of C. difficile

NIH researchers identify differences in gene activity in the brains of individuals with ADHD

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Novel nasal vaccine approach induces potent lung immunity and protection against SARS-CoV-2

Nerve cell discovery may improve treatment options for patients with neurodegenerative diseases

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

Research sheds light on cardiac pathology mechanisms of COVID-19

What are the current challenges and future directions of mRNA nanomedicine?

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