Therapy News and Research

RSS

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Elenagen™, a novel DNA plasmid therapy that previously demonstrated high clinical benefit and low toxicity in cancer patients, has now shown significant promise in alleviating chronic pain demonstrating a 90% success rate.

23 Jul 2025

Intranasal insulin safely and effectively reaches key memory regions of the brain

A groundbreaking brain imaging study from Wake Forest University School of Medicine confirms a vital step toward new Alzheimer's disease treatments: Intranasal insulin, delivered via a simple nasal spray, safely and effectively reaches key memory regions of the brain in older adults.

23 Jul 2025

New diagnostic test identifies head and neck cancer patients curable by surgery alone

Researchers developed a diagnostic test based on the LIMA1-alpha protein to distinguish patients with head and neck squamous cell carcinoma who can be cured with surgery alone, without the need for radiation or chemotherapy.

23 Jul 2025

Substance use disorders increase risk of unplanned hospital readmissions

People with any type of substance use disorder (SUD) stand a 24% higher risk of having an unplanned hospital readmission within 30 days of a previous discharge compared with those without the disorder, new UCLA-led research finds.

23 Jul 2025

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide significant benefits for cardiovascular, kidney, liver, joint, and sleep-related diseases. These effects extend beyond weight loss, suggesting anti-inflammatory mechanisms with broad potential for managing chronic diseases.

22 Jul 2025

GLP-1 receptor agonists linked to lower dementia risk in type 2 diabetes

GLP-1 receptor agonists, a class of drug used to treat type 2 diabetes, likely trump the widely prescribed metformin for curbing dementia risk in people with the condition, finds the largest study of its kind, published in the open access journal BMJ Open Diabetes Research & Care.

22 Jul 2025

UC Davis researchers pioneer safer gene therapy for vision loss

The UC Davis Department of Ophthalmology has received a five-year, $3.6 million grant from the National Eye Institute to explore a new way to treat vision loss using gene therapy.

22 Jul 2025

Breakthrough gene therapy reverses genetic deafness across age groups

Using gene therapy to treat hereditary deafness is safe and effective in both children and adults, according to new findings from a multicenter clinical trial.

22 Jul 2025

Mapping metformin’s kidney effects through spatial multi-omics

Metformin is a widely used first-line therapy for type 2 diabetes, and studies increasingly point to its protective effects on the kidney.

22 Jul 2025

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

Researchers identified a combination of two existing cancer drugs, letrozole and irinotecan, that reversed Alzheimer’s disease-related changes in brain cell networks and improved memory in mouse models. The study supports a multi-cell-type, network-correcting strategy as a promising path for future Alzheimer’s treatments.

22 Jul 2025

Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

22 Jul 2025

Mount Sinai researcher uncovers how the brain and body interact in aging and depression

In a comprehensive Genomic Press interview published in Brain Medicine today, Dr. Hamilton Se-Hwee Oh reveals groundbreaking insights into the complex dialogue between our brains and bodies that fundamentally shapes aging, depression, and neurodegenerative disease.

22 Jul 2025

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute.

22 Jul 2025

New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

Lidocaine poisonings and deaths rise sharply in the U.S.

Poisonings and deaths linked to the use of the local anaesthetic lidocaine have nearly tripled in the US over the past decade, finds an analysis of National Poison Data System (NPDS) reports, published online in the journal Regional Anesthesia & Pain Medicine.

22 Jul 2025

Australian study uncovers first potential prophylactic treatment against HTLV-1

Around 10 million people globally live with the life-threatening virus HTLV-1. Yet it remains a poorly understood disease that currently has no preventative treatments and no cure.

21 Jul 2025

Liver identified as key driver of cancer cachexia

Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, which further weakens the body.

21 Jul 2025

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.

21 Jul 2025

Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, neurodegeneration, and premature aging.

21 Jul 2025

Prime editing reverses symptoms of severe childhood neurological disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

21 Jul 2025

Therapy News and Research

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Intranasal insulin safely and effectively reaches key memory regions of the brain

New diagnostic test identifies head and neck cancer patients curable by surgery alone

Substance use disorders increase risk of unplanned hospital readmissions

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

GLP-1 receptor agonists linked to lower dementia risk in type 2 diabetes

UC Davis researchers pioneer safer gene therapy for vision loss

Breakthrough gene therapy reverses genetic deafness across age groups

Mapping metformin’s kidney effects through spatial multi-omics

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes

Mount Sinai researcher uncovers how the brain and body interact in aging and depression

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

New antibody therapy offers hope for fragile patients with Fanconi anemia

Lidocaine poisonings and deaths rise sharply in the U.S.

Australian study uncovers first potential prophylactic treatment against HTLV-1

Liver identified as key driver of cancer cachexia

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging

Prime editing reverses symptoms of severe childhood neurological disease

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News