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New blood test detects HPV-linked head and neck cancer with unmatched accuracy

A new liquid biopsy blood test could help detect cases of human papillomavirus (HPV)-associated head and neck cancers with significantly higher accuracy than currently used methods, including before patients develop symptoms, according to new Mass General Brigham research.

20 May 2025

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate synthetase 1 (CPS1) deficiency, a rare and life-threatening inborn error of metabolism. This pioneering approach chemically corrects the underlying mutation without cutting DNA, showing promise for precision treatment of ultrarare genetic disorders.

20 May 2025

Nanozymes offer promise for treating inflammation during pregnancy

Special care must be taken with illnesses during pregnancy, as not all drugs are compatible for mother and child.

20 May 2025

Age-related immune decline reduces CAR-T cell therapy efficacy

As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.

20 May 2025

Residual inflammation can linger in psoriasis patients despite skin treatment

New research shows that in patients with psoriasis, even though their skin responds well to treatment with biologics, inflammation can linger, leading to broader health implications such as obesity and cardiovascular and fatty liver disease.

20 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

This news might ruin your appetite — and summer

It's a marvel of food technology: ice cream that resists melting.

20 May 2025

Personality traits influence risk and persistence of insomnia

A study conducted at the Faculty of Medicine of the University of São Paulo (USP) in Brazil examined the influence of personality traits on the development and perpetuation of insomnia and found that there is a direct relationship between the two.

19 May 2025

Higher McCance Brain Care Score linked to lower stroke risk in women

Women with a higher McCance Brain Care Score (BCS) – a score that measures physical, lifestyle, and social-emotional factors – have a lower risk of experiencing a stroke or other cerebrovascular event reducing blood flow to the brain, according to a new study conducted by experts from Mass General Brigham.

19 May 2025

Light-activated immunotherapy approach could one day treat people with advanced stomach cancer

University of Texas at Dallas bioengineers, in collaboration with UT Southwestern Medical Center researchers, are developing an enhanced light-activated immunotherapy approach that could one day treat patients with stomach cancer that has spread throughout the abdomen.

19 May 2025

EMA designates allopurinol as first orphan drug for the treatment of Marfan syndrome

The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which as no cure to date.

19 May 2025

Repeated antibiotics in preterm infants linked to long-term lung problems

Repeated perinatal antibiotic exposure in very low-birth-weight preterm infants was associated with impaired lung function and a higher risk of asthma at early school age. The findings underscore the need for cautious antibiotic use and targeted respiratory health strategies in this high-risk group.

18 May 2025

Many heart failure patients miss out on life saving specialist care

If you have cancer, you expect to see an oncologist, but if you have heart failure you may or may not see a cardiologist.

18 May 2025

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide, with rising incidence linked to dietary and lifestyle changes.

18 May 2025

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

In the largest clinical genomic profiling study of non-Hispanic Black men with metastatic prostate cancer to date, researchers from Moffitt Cancer Center, University of Pennsylvania, University of California Los Angeles and the Veterans Affairs (VA) National Precision Oncology Program found key differences in tumor biology between non-Hispanic Black and non-Hispanic white veterans, but similar survival outcomes when both groups had equal access to care.

16 May 2025

Detailed personality tests may help personalize care for people with bipolar disorder

People with cancer, heart disease and other conditions have come to expect treatments that their medical teams "personalize" just for them, based on tests.

16 May 2025

Unlocking live single-cell functional insights

Discover how Bruker is advancing live single-cell functional analysis, helping to accelerate breakthroughs in immunology and beyond.

From Bruker Cellular Analysis 16 May 2025

Experts warn against unsupervised vitamin use and dietary trends in oncology

A new study coordinated by Dr. Salvatore Cortellino and Professor Antonio Giordano, President of the Sbarro Health Research Organization (SHRO) and molecular oncologist at Temple University and the University of Siena, offers a critical assessment of vitamin supplementation and popular dietary trends in the context of cancer prevention and treatment.

16 May 2025

Liquid biopsy advances precision medicine in gynecological cancers

A landmark review, now published in the Journal of Experimental & Clinical Cancer Research, offers a sweeping and authoritative synthesis on the use of liquid biopsy in gynecological oncology placing this emerging tool at the forefront of precision medicine for women.

16 May 2025

Aptamer announces new data at ASGCT

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, presented new data on its Optimer therapeutic delivery vehicle for liver fibrosis at the American Society of Gene and Cell Therapy (ASGCT) Annual Meeting in New Orleans, LA (13-17 May 2025).

From Aptamer Group 16 May 2025

Therapy News and Research

New blood test detects HPV-linked head and neck cancer with unmatched accuracy

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Nanozymes offer promise for treating inflammation during pregnancy

Age-related immune decline reduces CAR-T cell therapy efficacy

Residual inflammation can linger in psoriasis patients despite skin treatment

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

This news might ruin your appetite — and summer

Personality traits influence risk and persistence of insomnia

Higher McCance Brain Care Score linked to lower stroke risk in women

Light-activated immunotherapy approach could one day treat people with advanced stomach cancer

EMA designates allopurinol as first orphan drug for the treatment of Marfan syndrome

Repeated antibiotics in preterm infants linked to long-term lung problems

Many heart failure patients miss out on life saving specialist care

Long noncoding RNA ESSENCE identified as key driver of colorectal cancer progression

Genomic study of non-Hispanic Black veterans with prostate cancer yields key insights for precision medicine

Detailed personality tests may help personalize care for people with bipolar disorder

Unlocking live single-cell functional insights

Experts warn against unsupervised vitamin use and dietary trends in oncology

Liquid biopsy advances precision medicine in gynecological cancers

Aptamer announces new data at ASGCT

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