Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Government insured patients with breast cancer at increased risk of death

A retrospective study of nearly 9800 women with breast cancer who participated in randomized clinical trials was presented today at the 2019 San Antonio Breast Cancer Symposium.

13 Dec 2019

New technique may lead to earlier and easier detection of mouth and throat cancer

Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become advanced, partly because their location makes them difficult to see during routine clinical exams.

13 Dec 2019

New method to accurately assess dietary intake of bioactives

A new, objective way of measuring flavanol intake has been developed, which could help nutritional experts assess the link between these compounds and their health benefits at scale.

12 Dec 2019

Researchers making major inroads into finding the cause of different diseases

Australian researchers are making major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected by oxidative stress in the human body.

12 Dec 2019

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

In a clinical trial led by Yale Cancer Center and Smilow Cancer Hospital, researchers aim to exploit DNA mutations in the treatment of two blood and bone marrow cancers, a different tacit than the more traditional approach of blunting or switching off genetic mutations linked to cancer.

10 Dec 2019

Important biomarker may help in determining prognosis of brain cancer patients

A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent study published by a student researcher at the University of Cincinnati.

9 Dec 2019

Award to help advance development of diagnostic test for necrotizing enterocolitis

The Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health has awarded Chosen Diagnostics Inc, a spin-out company, a $299,641 Phase I Small Business Technology Transfer award.

9 Dec 2019

Beckman Coulter launches new DxH 690T hematology analyzer to support mid-size labs

Beckman Coulter , a global leader in clinical diagnostics, today announced the commercial launch of its new DxH 690T hematology analyzer.

From Beckman Coulter Life Sciences - Automation and Genomics 9 Dec 2019

Thermo Fisher Scientific to accelerate genomic profiling process in hematology and oncology labs

Clinical researchers who take a traditional sequential approach to analyze myeloid malignancies, a highly heterogeneous group of disorders, face a major hurdle: a laborious and time-consuming workflow.

From Thermo Fisher Scientific Inc. 9 Dec 2019

Ibrutinib-based therapy provides superior clinical outcomes in majority of CLL patients

The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) today announced results from an extended follow-up analysis of patients in its randomized Phase 3 clinical trial, E1912.

8 Dec 2019

Mologic starts major clinical trial to validate point-of-care COPD exacerbation alert system

Mologic Ltd, a leading developer of lateral flow and rapid diagnostic technologies, today announced that it has started a major clinical trial to validate the Company’s urine-based multi-biomarker self-test, Headstart, for the early detection of exacerbations in patients living with moderate to severe Chronic Obstructive Pulmonary Disease .

6 Dec 2019

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Investigators at Rutgers Cancer Institute of New Jersey have determined that an overabundance of a novel gene known as ADNP in an aggressive form of ovarian cancer may serve as a prognostic tool.

5 Dec 2019

Roswell Park-led scientists identify new defense mechanism against prostate cancer

A research team led by a scientist at Roswell Park Comprehensive Cancer Center has identified the molecule LRIG1 as an important endogenous tumor suppressor in prostate cancer. Writing in the journal Nature Communications, the team documents their findings from preclinical studies showing that overexpression of the LRIG1 protein inhibits prostate cancer development, while reducing naturally occurring LRIG1 promotes prostate tumor development.

3 Dec 2019

Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

MRI-guided ultrasound ablation: safer better treatment for prostate cancer

Prostate cancer may soon be treated more effectively using ultrasound at therapeutic levels, without the significant and distressing side effects of more traditional treatments. A new study presented on December 2, 2019, presents the outcome of using focused ultrasound ablation under MRI guidance in a novel procedure that can be used to treat both benign and malignant enlargement of the prostate gland.

2 Dec 2019

Simple urine test at home could revolutionize diagnosis of prostate cancer

A simple urine test under development for prostate cancer detection can now use urine samples collected at home - according to new research from University of East Anglia and the Norfolk and Norwich University Hospital.

28 Nov 2019

Home urine testing kit for prostate cancer could come soon

A new study from the University of East Anglia and the Norfolk and Norwich University Hospital may lead to people being able to test for prostate cancer from home, using urine samples. The study, which was published in the journal BioTechniques, describes a simple home urine collection test which can detect aggressive prostate cancer, and providing information on whether it requires to be treated, up to 5 years earlier than the comparable diagnostic methods of today.

28 Nov 2019

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Oligomerix, Inc., a privately held company pioneering the development of tau oligomer inhibitors for Alzheimer's disease and related neurodegenerative disorders, and the Feinstein Institutes for Medical Research announced today the publication of preclinical data demonstrating that an oral small molecule drug inhibits the formation of neurotoxic tau oligomers in an animal model of tau aggregation most relevant to AD.

26 Nov 2019

Researchers find pupillary changes in high-school athletes after high-acceleration head impacts

Researchers from the University of Michigan found significant pupillary changes in high-school football athletes after they had sustained a high-acceleration head impact.

26 Nov 2019

New electrochemical CRISPR biosensor can help improve diagnosis of diseases

The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors - which scientists can use to edit genetic material - in order to better diagnose diseases such as cancer.

25 Nov 2019

Biomarker News and Research

Further Reading

Government insured patients with breast cancer at increased risk of death

New technique may lead to earlier and easier detection of mouth and throat cancer

New method to accurately assess dietary intake of bioactives

Researchers making major inroads into finding the cause of different diseases

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

Important biomarker may help in determining prognosis of brain cancer patients

Award to help advance development of diagnostic test for necrotizing enterocolitis

Beckman Coulter launches new DxH 690T hematology analyzer to support mid-size labs

Thermo Fisher Scientific to accelerate genomic profiling process in hematology and oncology labs

Ibrutinib-based therapy provides superior clinical outcomes in majority of CLL patients

Mologic starts major clinical trial to validate point-of-care COPD exacerbation alert system

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Roswell Park-led scientists identify new defense mechanism against prostate cancer

Inhibition of a protease could improve the treatment of IBD, study shows

MRI-guided ultrasound ablation: safer better treatment for prostate cancer

Simple urine test at home could revolutionize diagnosis of prostate cancer

Home urine testing kit for prostate cancer could come soon

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Researchers find pupillary changes in high-school athletes after high-acceleration head impacts

New electrochemical CRISPR biosensor can help improve diagnosis of diseases

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

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