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Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

Peer-led navigation program improves mental health outcomes for racially and ethnically minoritized veterans

Research scientists led by Johanne Eliacin, PhD, of the U.S. Department of Veterans' Affairs (VA) and Regenstrief Institute, have developed PARTNER-MH, an innovative, peer-led patient navigation program to support racially and ethnically minoritized veterans seeking mental healthcare, regardless of the types of mental health services needed or their mental health diagnoses.

14 Sep 2023

Multi-omics study offers insights into psoriasis treatment

Researchers use a multi-omics approach combining immune cell-enriched scRNA-seq, microarray analysis, and immunohistochemistry to elucidate the translational role of anti-IL-17A in suppressing the autoimmune functions of T17 cells, thereby effectively treating human psoriasis.

14 Sep 2023

Researchers receive £2.66M to test new immunotherapeutic strategy for non-small cell lung cancer

University of Liverpool researchers have secured £2.66m Medical Research Council funding to clinically test a novel immunotherapeutic strategy for non-small cell lung cancer – one of the most deadly cancers.

13 Sep 2023

Comparing HIV PrEP medications: Study explores hypertension risk in adults on TAF vs. TDF

The risk of hypertension and statin initiation in adults starting Human Immunodeficiency Virus Pre-exposure prophylaxis.

13 Sep 2023

Both high- and normal-protein diets are effective for weight loss in adults with Type 2 diabetes

New findings from the University of Alabama at Birmingham indicate that the type of protein in the diet is not as important as the overall amount of weight loss for those with Type 2 diabetes.

12 Sep 2023

Unified and concentrated lung cancer advocacy program results in 25% increase in research funding

A unified and concentrated lung cancer advocacy program in the United States resulted in a 25 percent increase in funding to a U.S.-based lung cancer research program, according to a presentation given today at the International Association for the Study of Lung Cancer 2023 World Conference on Lung Cancer in Singapore.

12 Sep 2023

Study reveals key reproductive factors that may increase lung cancer risk in women

A study presented at the International Association for the Study of Lung Cancer 2023 World Conference on Lung Cancer revealed that key reproductive factors such as early menopause, shortened reproductive span, and early age at first birth are associated with elevated risks of lung cancer in women.

12 Sep 2023

Intensity-modulated radiation therapy reduces radiation exposure to heart and lungs in NSCLC patients

Intensity-modulated radiation therapy (IMRT) should be the preferred choice when treating patients with locally advanced non-small cell lung cancer (NSCLC), as it reduces radiation exposure to the heart and lungs, according to researchers at The University of Texas MD Anderson Cancer Center.

12 Sep 2023

Natural compound in turmeric may be as effective as omeprazole for treating indigestion

A natural compound found in the culinary spice turmeric may be as effective as omeprazole - a drug used to curb excess stomach acid - for treating indigestion symptoms, suggests the first study of its kind, published online in the journal BMJ Evidence-Based Medicine.

12 Sep 2023

Stem cells can be used to repair damaged lung tissue in COPD patients

For the first time, researchers have shown it is possible to repair damaged lung tissue in patients with chronic obstructive pulmonary disease (COPD) using the patients' own lung cells.

12 Sep 2023

Effective treatment for lower urinary tract symptoms linked to lower mortality risk in older men

Effective treatment for lower urinary tract symptoms (LUTS) in men aged 50 or older is associated with a lower risk of death over the next few years reports a study in the October issue of The Journal of Urology, an Official Journal of the American Urological Association.

11 Sep 2023

Oxford University study administers first-ever vaccine against Crimean-Congo hemorrhagic fever

A University of Oxford study has administered a new vaccine against tick-borne virus Crimean-Congo hemorrhagic fever (CCHF) to volunteers for the first time.

11 Sep 2023

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

The Buck Institute for Research on Aging has received a $3.5 million federal grant to lead the first-ever double-blind, randomized, placebo-controlled clinical trial to understand the effects of ketone ester supplementation on frailty, a condition of vulnerability which develops following age-related decline in multiple physiological systems.

11 Sep 2023

Mature gut microbiota in early infancy may protect against wheezing and allergies

Babies and young children with more mature communities of bacteria present in their gut are less likely to develop allergy-related wheezing or asthma, according to research presented at the European Respiratory Society International Congress in Milan, Italy.

11 Sep 2023

CheckMate 227 trial: Nivolumab + ipilimumab shows remarkable six-year survival benefits in metastatic NSCLC

The International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2023 in Singapore is set to witness a monumental breakthrough in the field of metastatic non-small cell lung cancer (NSCLC) treatment.

11 Sep 2023

Modified adenocarcinoma classification improves reproducibility and aligns with clinical reality

A modified adenocarcinoma classification approach significantly enhances reproducibility and may be an improvement on the existing World Health Organization classification system, according to research unveiled at the International Association for the Study of Lung Cancer (IASLC) 2023 World Conference on Lung Cancer in Singapore.

11 Sep 2023

Osimertinib plus chemotherapy shows significant PFS benefit in advanced EGFR-mutated NSCLC

Osimertinib plus chemotherapy demonstrated a statistically significant and clinically meaningful progression-free survival benefit compared to osimertinib alone, according to research presented today at the International Association for the Study of Lung Cancer (IASLC) 2023 World Conference on Lung Cancer in Singapore.

11 Sep 2023

Extended pleurectomy decortication plus chemotherapy associated with worse outcomes for mesothelioma patients

Extended pleurectomy decortication combined with chemotherapy is associated with worse survival outcomes, a higher incidence of serious adverse events, and a diminished quality of life compared to platinum and pemetrexed chemotherapy alone, according to research presented today the International Association for the Study of Lung Cancer (IASLC) 2023 World Conference on Lung Cancer in Singapore.

11 Sep 2023

Durvalumab shows tolerable surgical safety profile in patients with resectable NSCLC

Adding perioperative durvalumab to neoadjuvant chemotherapy did not adversely impact surgery in patients with resectable NSCLC and was associated with a tolerable surgical safety profile, according to research presented today from the phase 3 AEGEAN trial at the International Association for the Study of Lung Cancer 2023 World Conference on Lung Cancer in Singapore.

11 Sep 2023

Clinical Trial News and Research

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Peer-led navigation program improves mental health outcomes for racially and ethnically minoritized veterans

Multi-omics study offers insights into psoriasis treatment

Researchers receive £2.66M to test new immunotherapeutic strategy for non-small cell lung cancer

Comparing HIV PrEP medications: Study explores hypertension risk in adults on TAF vs. TDF

Both high- and normal-protein diets are effective for weight loss in adults with Type 2 diabetes

Unified and concentrated lung cancer advocacy program results in 25% increase in research funding

Study reveals key reproductive factors that may increase lung cancer risk in women

Intensity-modulated radiation therapy reduces radiation exposure to heart and lungs in NSCLC patients

Natural compound in turmeric may be as effective as omeprazole for treating indigestion

Stem cells can be used to repair damaged lung tissue in COPD patients

Effective treatment for lower urinary tract symptoms linked to lower mortality risk in older men

Oxford University study administers first-ever vaccine against Crimean-Congo hemorrhagic fever

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

Mature gut microbiota in early infancy may protect against wheezing and allergies

CheckMate 227 trial: Nivolumab + ipilimumab shows remarkable six-year survival benefits in metastatic NSCLC

Modified adenocarcinoma classification improves reproducibility and aligns with clinical reality

Osimertinib plus chemotherapy shows significant PFS benefit in advanced EGFR-mutated NSCLC

Extended pleurectomy decortication plus chemotherapy associated with worse outcomes for mesothelioma patients

Durvalumab shows tolerable surgical safety profile in patients with resectable NSCLC

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