Efficacy News and Research

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Paxlovid enhances treatment options for COVID-19 patients

The design, synthesis, and mechanism of action of Paxlovid.

6 Feb 2024

Hydrogel with built-in antibiofilm and antioxidative functions promotes faster healing of infected chronic wounds

A novel hydrogel dressing was developed recently to combat both these undesirable characteristics and tested for its effects on diabetic-infected wound healing.

5 Feb 2024

HIV patients have been less vaccinated with the full initial regimen against COVID-19

In December, the journal Vaccines published an analysis of COVID-19 vaccination coverage among people with HIV in Catalonia between December 2020 and July 2022.

5 Feb 2024

First gene therapy trial aims to restore hearing in children

The aim of this clinical trial, which has just received approval in France, is to assess the safety and efficacy of a new gene therapy drug in children aged between 6 and 31 months with profound hearing loss.

5 Feb 2024

PI3K/AKT and MEK/ERK pathways targeted in new therapy for docetaxel-resistant prostate cancer

A team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and the Urologic Tumours Unit of the Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) have found a new therapeutic strategy for patients with a specific subtype of metastatic prostate cancer resistant to standard chemotherapy treatment with docetaxel.

5 Feb 2024

Clinique and Mount Sinai partner to establish the Mount Sinai-Clinique Healthy Skin Dermatology Center

Clinique and Icahn School of Medicine at Mount Sinai today announced a philanthropic partnership to establish the Mount Sinai-Clinique Healthy Skin Dermatology Center.

5 Feb 2024

Does Sudarshan Kriya Yoga (SKY) practice reduce stress and increase well-being in practicing physicians?

The efficacy of SKY in reducing psychological distress and enhancing wellness among physicians at risk of burnout.

5 Feb 2024

Black garlic may have anti-cancer and anti-inflammatory properties

The anti-inflammatory and anti-cancer properties of black garlic (BG).

5 Feb 2024

What does the future hold for obesity medication development?

The safety, clinical implications, and challenges of obesity pharmacotherapies based on entero-pancreatic hormone- treatments.

5 Feb 2024

Phase 3 trial of new malaria vaccine reveals promising results in protecting children

Today, peer-reviewed results from a Phase 3 efficacy trial of the R21/Matrix-M™ malaria vaccine were published in The Lancet. The study was conducted across multiple sites in four African countries with 4,800 children aged 5-36 months.

5 Feb 2024

Breakthrough obesity treatments on the horizon, rivaling surgery's success

New obesity pharmacotherapies, including GLP-1 receptor agonists and combinations of entero-pancreatic hormones, show promise in achieving significant weight loss, potentially rivaling bariatric surgery's effectiveness.

4 Feb 2024

XBB.1.5 updated COVID vaccine booster offers 54% increased protection against symptomatic infection

Early estimates show the 2023-24 updated monovalent XBB.1.5 COVID-19 vaccine offers significant protection against symptomatic infection, with effectiveness varying by age and time since vaccination.

4 Feb 2024

Has a decade of maternal pertussis vaccination reduced its effectiveness?

Research indicates maternal immunization against pertussis remains crucial for newborn protection despite concerns of reduced vaccine effectiveness over time, underscoring its vital role in preventing infant mortality.

3 Feb 2024

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

ASU professor offers insights on what may be coming from Neuralink’s PRIME study

This week, Neuralink's Elon Musk announced that human clinical trials have begun on its Precise Robotically Implanted Brain-Computer Interface (PRIME) study, a medical device trail that uses wireless, brain-computer interface designed to enable people with paralysis to control external devices with their thoughts.

2 Feb 2024

MACUSTAR extends Europe-wide clinical study on intermediate age-related macular degeneration

The MACUSTAR consortium is extending the duration of a Europe-wide clinical study on age-related macular degeneration (AMD) under the coordination of the Department of Ophthalmology at the University Hospital Bonn (UKB).

2 Feb 2024

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.

2 Feb 2024

Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor functions, which eventually leads to death within 5 years of its onset.

1 Feb 2024

Specific epigenetic pathway found to be involved in the development of melanoma drug resistance

One of the major challenges in cancer research and clinical care is understanding the molecular basis for therapeutic resistance as a major cause of long term treatment failures.

1 Feb 2024

Gingko biloba compound injections linked to better stroke outcomes

People with ischemic (clot-caused) stroke had better early recovery of cognitive function if treated with intravenous injections of a combination of biologically active components of ginkgo biloba during the first two weeks after the stroke, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

Efficacy News and Research

Paxlovid enhances treatment options for COVID-19 patients

Hydrogel with built-in antibiofilm and antioxidative functions promotes faster healing of infected chronic wounds

HIV patients have been less vaccinated with the full initial regimen against COVID-19

First gene therapy trial aims to restore hearing in children

PI3K/AKT and MEK/ERK pathways targeted in new therapy for docetaxel-resistant prostate cancer

Clinique and Mount Sinai partner to establish the Mount Sinai-Clinique Healthy Skin Dermatology Center

Does Sudarshan Kriya Yoga (SKY) practice reduce stress and increase well-being in practicing physicians?

Black garlic may have anti-cancer and anti-inflammatory properties

What does the future hold for obesity medication development?

Phase 3 trial of new malaria vaccine reveals promising results in protecting children

Breakthrough obesity treatments on the horizon, rivaling surgery's success

XBB.1.5 updated COVID vaccine booster offers 54% increased protection against symptomatic infection

Has a decade of maternal pertussis vaccination reduced its effectiveness?

CAR T cells target senescent cells, improve healthspan in mice

ASU professor offers insights on what may be coming from Neuralink’s PRIME study

MACUSTAR extends Europe-wide clinical study on intermediate age-related macular degeneration

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Specific epigenetic pathway found to be involved in the development of melanoma drug resistance

Gingko biloba compound injections linked to better stroke outcomes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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