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New method for direct identification of antigens

The immune system is a vital part of our defenses against pathogens, but it can also attack host tissues, resulting in autoimmune disease. The antigens that induce destructive immune reactions can now be identified directly - without any prior knowledge of their possible structure.

11 Apr 2012

Stealth announces results from three Bendavia Phase I clinical trials for mitochondrial dysfunction

Stealth Peptides Inc., a privately held biopharmaceutical company developing innovative therapies for diseases with unmet medical needs, announced today the results from three Phase I clinical trials of Bendavia, a novel compound that targets the mitochondrion to treat mitochondrial dysfunction, including ischemia reperfusion and microvascular injury.

9 Apr 2012

Nuron Biotech licenses DNA amyloid beta 42 vaccine for AD

Nuron Biotech, Inc. today announced it has licensed from VITRUVIAN BioMedical, Inc. a gene-based (DNA) amyloid beta 42 (Aβ42) vaccine in preclinical development for Alzheimer's disease (AD).

9 Apr 2012

Researchers discover two molecules that control liver glucose production

In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose---- the simple sugar that is the source of energy in human cells and the central player in diabetes.

9 Apr 2012

NIMH honors SUNY Downstate professor with MERIT award

Todd C. Sacktor, M.D., distinguished professor of physiology and pharmacology and of neurology at SUNY Downstate Medical Center, has received a MERIT (Method to Extend Research in Time) award from the National Institute of Mental Health (NIMH) for his research on memory.

7 Apr 2012

Scientists uncover structure and operating mechanism of TPPII

Uncontrolled or inaccurate degradation of cellular proteins can lead to diseases like cancer or Alzheimer's disease. Scientists of the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, have now uncovered the structure and the operating mechanism of an important component of the human cellular degradation machinery, tripeptidyl peptidase II.

5 Apr 2012

µ-PIIIA conotoxin can be effective in controlling cancer pain

Hidden in the mud, the cone snail Conus purpurascens lies in wait for its victims. It attracts its prey, fish, with its proboscis, which can move like a worm, protruding from the mud. Once a fish approaches out of curiosity, the snail will rapidly shoot a harpoon at it, which consists of an evolutionarily modified tooth. The paralyzed victim then becomes an easy meal. It takes the venomous cone snail about two weeks to digest a fish. During this time, its venomous harpoon is also replaced.

5 Apr 2012

New SORL1 gene causes early-onset Alzheimer's

A new gene that causes early-onset of Alzheimer's disease has been discovered by the research team of Dominique Campion at the Insert unit 1079 "Genetics of cancer and neuropsychiatric diseases" in Rouen.

5 Apr 2012

Dyax, GE Healthcare partner to develop and commercialize c-Met imaging peptides

GE Healthcare, a unit of GE, and Dyax Corp. today announced a licensing agreement for the development and commercialization of peptides binding to c-Met, which provides upfront, milestone, and royalty payments to Dyax.

2 Apr 2012

Scientists explore number of strategies to prevent anesthesia-induced injury in infants

Recent clinical studies have shown that general anesthesia can be harmful to infants, presenting a dilemma for both doctors and parents. But new research at Wake Forest Baptist Medical Center may point the way to treatment options that protect very young children against the adverse effects of anesthesia.

29 Mar 2012

Helix BioMedix 2011 revenue increases 122% to record $1.9 million

Helix BioMedix, Inc., a developer of bioactive peptides, today announced financial results for the year ended December 31, 2011.

29 Mar 2012

EU-funded project to help control appetite, combat obesity

The University of Liverpool is leading a £6milllion European project to develop and test new food products with satiating qualities to help control appetite, manage weight and combat obesity.

29 Mar 2012

UofL researcher receives patent for novel biochemical discovery

University of Louisville researchers are a step closer to eliminating periodontal disease through their work to develop synthetic molecules that prevent a bacteria responsible for the disease from spreading throughout the mouth.

28 Mar 2012

Study identifies major gene affecting chronic pain sensitivity

Nearly one in five people suffers from the insidious and often devastating problem of chronic pain.

27 Mar 2012

Uppsala University researchers identify promising biomarkers for ASD

An important step towards developing a rapid, inexpensive diagnostic method for autism has been take by Uppsala University, among other universities. Through advanced mass spectrometry the researchers managed to capture promising biomarkers from a tiny blood sample.

23 Mar 2012

Elevated Aβ peptide levels may lead to onset of AD

The effects of the bacterial endotoxin lipopolysaccharide (LPS) has been found to elevate amyloid beta (Aβ) peptide levels in the brain, leading to short-term deficits in learning.

21 Mar 2012

Sexually rejected male fruit flies binge on alcohol more than sexually satisfied peers: Study

Male fruit flies whose sexual advances are rejected by females, turn to alcohol finds a new study. Scientists at the University of California, San Francisco discovered that rejected male flies have a tiny molecule in their brain that pushes them to drink far more than their sexually satisfied counterparts. The levels of the molecule, neuropeptide F, were higher in sexually satisfied males than in those who got no sex, leading scientists to speculate that their work could shed light on brain mechanisms behind human addiction. A similar human molecule - neuropeptide Y - may also link social triggers to behaviors such as heavy drinking and drug abuse, according to the study published in Science journal.

18 Mar 2012

ZO Skin Health to launch new comprehensive medical skincare line

ZO Skin Health By Zein Obagi, M.D. is pleased to announce the global launch of a new comprehensive medical skincare line, ZO Medical, at the American Academy of Dermatology Annual Meeting.

17 Mar 2012

Neuropeptide F in the fly's brain governs behavior linked with addiction

Sexually deprived male fruit flies exhibit a pattern of behavior that seems ripped from the pages of a sad-sack Raymond Carver story: when female fruit flies reject their sexual advances, the males are driven to excessive alcohol consumption, drinking far more than comparable, sexually satisfied male flies.

16 Mar 2012