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Study documents reversal of established medical practices in last decade

While there is an expectation that newer medical practices improve the standard of care, the history of medicine reveals many instances in which this has not been the case. Reversal of established medical practice occurs when new studies contradict current practice. Reporters may remember hormone replacement therapy as an example of medical reversal. A new analysis published in Mayo Clinic Proceedings documents 146 contemporary medical practices that have subsequently been reversed.

23 Jul 2013

Researchers develop microbial washing technique to decontaminate fetal tissues

The use of central nervous system fetal tissues derived from routine elective abortions to provide stem cells for transplantation procedures aimed at restoring damage done by neurodegenerative diseases is an established therapy.

23 Jul 2013

Melatonin pre-treatment greatly increases cell survival, say researchers

When melatonin, a hormone secreted by the pineal gland, was used as a pre-treatment for mesenchymal stem cells prior to their transplantation into the brains of laboratory animals to repair damage from stroke, researchers in China found that the stem cells survived longer after transplantation. Previous studies had shown that 80 percent of transplanted MSCs died within 72 hours of transplantation.

23 Jul 2013

Scientists identify circuitry in brain that drives compulsive drinking in rats

A research team led by scientists from the Ernest Gallo Clinic and Research Center at the University of California, San Francisco has identified circuitry in the brain that drives compulsive drinking in rats, and likely plays a similar role in humans.

23 Jul 2013

NF-κB protein complex may boost immune system to eliminate cancerous cells

Researchers at Moffitt Cancer Center and Tianjin Medical University Cancer Institute and Hospital in China have discovered a gene expression signature that may lead to new immune therapies for lung cancer patients.

23 Jul 2013

Imprimis to begin IRB-approved Impracor Phase III trial for acute pain associated with OA of the knee

Imprimis Pharmaceuticals, Inc., which is focused on the commercialization of compounded drug formulations utilizing the FDA 505(b)(2) development pathway, today announced it has received IRB approval for its Phase III clinical trial protocol of its lead product candidate, Impracor.

23 Jul 2013

New finding provides fresh hope for women with oestrogen receptor positive breast cancer

A new finding provides fresh hope for the millions of women worldwide with oestrogen receptor positive breast cancer. Australian scientists have shown that a specific change, which occurs when tumours become resistant to anti-oestrogen therapy, might make the cancers susceptible to treatment with chemotherapy drugs.

23 Jul 2013

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

P53 is a tumor suppressor gene. The gene encodes for a protein that monitors the state of the cell. If something goes wrong, it stops the cell from dividing or causes the cell to commit suicide. I call it the “guardian of the genome” as it is the molecule that seems to keep cells normal. It is one of our big defenses against cancer.

22 Jul 2013

Great Lakes NeuroTechnologies receives patent for Parkinson’s disease monitoring technology

Great Lakes NeuroTechnologies announced today they have received allowance of claims from the U.S. Patent Office for an application covering their system and method of stimulating the brain during sleep to treat movement disorder symptoms.

22 Jul 2013

Initial polytherapy effectively improves prognosis of infantile spasms

Adrenocorticotropic hormone is recommended worldwide as an initial therapy for infantile spasms. However, infantile spasms in about 50% of children cannot be fully controlled by adrenocorticotropic hormone monotherapy, seizures recur in 33% of patients who initially respond to adrenocorticotropic hormone monotherapy, and side effects are relatively common during adrenocorticotropic hormone treatment.

22 Jul 2013

Experts team up to launch International Centre for Mental Health Social Research

Mental health experts from around the world are teaming up to undertake a unique research programme applying social science to mental health practice.

22 Jul 2013

Monash University researchers provide novel pathways to develop treatments for diseases

Monash University researchers have gained new insight into the early stages of our immune response, providing novel pathways to develop treatments for diseases from multiple sclerosis to cancer.

22 Jul 2013

Jersey Shore to present free educational conference focusing on thyroid cancer patients, survivors

On Friday, August 2, 2013, Jersey Shore, in partnership with Meridian Cancer Care and the Light of Life Foundation, will present a free educational conference featuring Meridian Health specialists.

22 Jul 2013

New research project has potential to treat human deafness and loss of balance

The sounds of success are ringing at Kansas State University through a research project that has potential to treat human deafness and loss of balance.

20 Jul 2013

Children with unilateral hearing loss are more likely to struggle in school

Children born with a complete absence of the external ear canal, even if only one ear is affected, are more likely than their peers to struggle in school, according to new research at Washington University School of Medicine in St. Louis.

20 Jul 2013

Investigators report complete catalog of genes expressed in retina

Investigators at Massachusetts Eye and Ear and Harvard Medical School have published the most thorough description of gene expression in the human retina reported to date. In a study published today in the journal BMC Genomics, Drs. Michael Farkas, Eric Pierce and colleagues in the Ocular Genomics Institute at Mass. Eye and Ear reported a complete catalog of the genes expressed in the retina.

20 Jul 2013

Absence of Shp-2 enzyme near cartilage cells can lead to multiple benign cartilage tumors in mice

Rhode Island Hospital researchers have found that the absence of the Shp-2 enzyme near specialized cartilage cells can lead to the development of multiple benign cartilage tumors in mice, a model that recapitulates the rare human tumor syndrome metachondromatosis.

20 Jul 2013

Researchers identify mechanism behind pediatric solid tumors

Most of the time, it takes decades of accumulating genetic errors for a tumor to develop. While this explains the general occurrence of cancer in adults, it leaves a gap in understanding of the cause of pediatric tumors.

20 Jul 2013

Researchers uncover evidence that genetic changes play role in resistance to deadly disease

Researchers have long understood that genetics can play a role in how susceptible people are to contracting cholera, but a team of Harvard scientists is now uncovering evidence of genetic changes that might also help protect some people from contracting the deadly disease.

20 Jul 2013

Researchers demonstrate that 2-drug combination can eliminate cancer

New research conducted by Harvard scientists is laying out a roadmap to one of the holy grails of modern medicine - a cure for cancer.

20 Jul 2013

Therapy News and Research

Study documents reversal of established medical practices in last decade

Researchers develop microbial washing technique to decontaminate fetal tissues

Melatonin pre-treatment greatly increases cell survival, say researchers

Scientists identify circuitry in brain that drives compulsive drinking in rats

NF-κB protein complex may boost immune system to eliminate cancerous cells

Imprimis to begin IRB-approved Impracor Phase III trial for acute pain associated with OA of the knee

New finding provides fresh hope for women with oestrogen receptor positive breast cancer

p53 and cancer research: an interview with Professor Sir David Lane, Scientific Director of the Ludwig Institute for Cancer Research

Great Lakes NeuroTechnologies receives patent for Parkinson’s disease monitoring technology

Initial polytherapy effectively improves prognosis of infantile spasms

Experts team up to launch International Centre for Mental Health Social Research

Monash University researchers provide novel pathways to develop treatments for diseases

Jersey Shore to present free educational conference focusing on thyroid cancer patients, survivors

New research project has potential to treat human deafness and loss of balance

Children with unilateral hearing loss are more likely to struggle in school

Investigators report complete catalog of genes expressed in retina

Absence of Shp-2 enzyme near cartilage cells can lead to multiple benign cartilage tumors in mice

Researchers identify mechanism behind pediatric solid tumors

Researchers uncover evidence that genetic changes play role in resistance to deadly disease

Researchers demonstrate that 2-drug combination can eliminate cancer

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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