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Pollutant from forest and crop fires induces genetic damage in human lung cells

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

24 Oct 2017

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

As cells with a propensity for cancer break down food for energy, they reach a fork in the road: They can either continue energy production as healthy cells, or shift to the energy production profile of cancer cells.

24 Oct 2017

Stem cell researchers make advance toward long-lasting blood vessel repair

Stem cell researchers at Emory University School of Medicine have made an advance toward having a long-lasting "repair caulk" for blood vessels. The research could form the basis of a treatment for peripheral artery disease, derived from a patient's own cells. Their results were recently published in the journal Circulation.

24 Oct 2017

Scientists develop physiological approach to restore gut’s ecosystem in various diseases

The trillions of microbes living in a mammal's intestine play an important role in the host's metabolism and immunity. The composition of microbiota is maintained by antimicrobial proteins secreted from intestinal cells.

24 Oct 2017

Research provides insight into how two stands of double helix separate during replication

Life would be impossible if the DNA in dividing cells were replicated with anything less than near-perfect precision. Every time a nucleated cell commits to becoming two cells, every "letter" of its genome must be replicated once and only once.

24 Oct 2017

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus.

24 Oct 2017

Measuring biological samples using SNAP

My group is interested in host pathogen interaction and we mainly focus on how bacteria enter cells. In essence, the idea is that if you can prevent bacteria from entering cells, then you will prevent illness.

From Bruker Nano Surfaces and Metrology 24 Oct 2017

Lung microbiome plays major role in asthma severity and response to treatment

While the microbiome has gained significant attention for its impact on digestive health in recent years, its effect on lung disease has largely remained unstudied.

24 Oct 2017

Study identifies protein that plays crucial role in diabetic retinopathy

For millions of Americans, their world is dissolving into an unrecognizable blur. Diabetic retinopathy is an eye disease affecting one-third of the estimated 30 million Americans who struggle with diabetes. As the patients' vision slowly fades, it never recovers and few treatments are available.

24 Oct 2017

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Melanomas caused by sun exposure have been matched with targeted treatments and immunotherapies, in many cases dramatically extending patients' lives. However, there are other kinds of melanoma not related to sun exposure and because they are caused by different genetic changes, they are not susceptible to the same targeted treatments.

23 Oct 2017

Brazilian scientists examine how benzopyrene can cause cancer

Benzo[a]pyrene is a potent carcinogen and mutagen present in cigarette smoke, automotive exhaust, burnt wood fumes, barbecued and smoked meat etc.

23 Oct 2017

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

A key enzyme that helps our proteins fold and function properly may also be a good therapeutic target to improve blood vessel health in diseases like diabetes and atherosclerosis, scientists say.

23 Oct 2017

KU Leuven researchers identify new rapid response mechanism against bacterial infections

When bacteria enter our body, they kick-start a powerful immune response. But this chain of reactions doesn't fully account for our immediate responses. Researchers at KU Leuven, Belgium, show that so-called ion channels play a key role as 'first responders'.

23 Oct 2017

E-cigarettes may activate distinctive and potentially damaging immune responses, study reveals

A new study, published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, suggests that e-cigarettes may stimulate distinct immune responses along with the same responses that cigarettes stimulate resulting in lung disease.

23 Oct 2017

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Notch is one of the most frequently mutated genes in chronic lymphocytic leukemia (CLL), the most common leukemia in adults in the United States. It is also often mutated in other common B cell tumors, such as mantle cell lymphoma.

23 Oct 2017

Discovery of novel mechanism in the gut microbiome has implications for people with IBD

Many people associate the word "bacteria" with something dirty and disgusting. Dr. Pere Santamaria disagrees. Called the microbiome, the bacteria in our bodies have all kinds of positive effects on our health, Santamaria says. "The bacteria we have in our gut actually have many beneficial functions. They help in our digestion, prevent infection by pathogens and educate our immune system on what to fight."

23 Oct 2017

Research provides insight on Y-shape in proteins associated with glaucoma

So unheard of was what researchers discovered in a protein associated with glaucoma that for over two years they ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially saw.

23 Oct 2017

Queen's University Belfast leads new research to better understand biology of prostate cancer

Queen's University Belfast has led the world's largest research study using a diagnostic test developed by Almac Diagnostics, to better understand the biology of prostate cancer tumors, which could lead to a transformation in how prostate cancer is diagnosed and treated.

23 Oct 2017

Study elucidates how obesity makes breast cancer more aggressive

Obesity leads to the release of cytokines into the bloodstream which impact the metabolism of breast cancer cells, making them more aggressive as a result. Scientists from Helmholtz Zentrum München, Technische Universität München, and Heidelberg University Hospital report on this in 'Cell Metabolism'. The team has already been able to halt this mechanism with an antibody treatment.

23 Oct 2017

Nutritionist highlights importance of vitamin D for pregnant women and new mums

Every mother-to-be wants to ensure they do all they can to give their baby the best start in life. Growing a healthy baby starts with ensuring optimal nutrition whilst you’re pregnant.

From BetterYou Ltd 23 Oct 2017

B Cell News and Research

Pollutant from forest and crop fires induces genetic damage in human lung cells

Researchers map molecular events that direct cells' energy metabolism down the cancerous path

Stem cell researchers make advance toward long-lasting blood vessel repair

Scientists develop physiological approach to restore gut’s ecosystem in various diseases

Research provides insight into how two stands of double helix separate during replication

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Measuring biological samples using SNAP

Lung microbiome plays major role in asthma severity and response to treatment

Study identifies protein that plays crucial role in diabetic retinopathy

Study finds lung cancer driver ALK-fusion in mucosal melanoma

Brazilian scientists examine how benzopyrene can cause cancer

Key enzyme may be therapeutic target to treat diabetes-related blood vessel damage

KU Leuven researchers identify new rapid response mechanism against bacterial infections

E-cigarettes may activate distinctive and potentially damaging immune responses, study reveals

Penn researchers provide new insights into how Notch drives growth of B-cell cancers

Discovery of novel mechanism in the gut microbiome has implications for people with IBD

Research provides insight on Y-shape in proteins associated with glaucoma

Queen's University Belfast leads new research to better understand biology of prostate cancer

Study elucidates how obesity makes breast cancer more aggressive

Nutritionist highlights importance of vitamin D for pregnant women and new mums

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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