Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study reveals how adults exposed to alcohol go on to develop compulsive drinking behaviors

Occasional binge drinking isn't uncommon, but about 30 percent of all adults exposed to alcohol go on to engage in compulsive drinking behaviors despite negative effects and consequences - a major feature of alcohol use disorder.

22 Nov 2019

University of Sheffield receives Queen's Anniversary Prize for innovation in neuroscience

Neuroscience research at the University of Sheffield has been recognized by Her Majesty The Queen for delivering real benefits in improving patient outcomes for people living with some of the most devastating neurodegenerative diseases.

22 Nov 2019

Sphingolipids associated with heart disease in African Americans with lupus

When it comes to cholesterol, we've come to accept a simple narrative. Our risk of heart disease is lower when we have more "good cholesterol," or high-density lipoproteins (HDL), and less "bad cholesterol," or low-density lipoproteins (LDL) and triglycerides.

21 Nov 2019

BrainStorm publishes NurOwn ALS Phase 2 randomized clinical trial results in Neurology

BrainStorm Cell Therapeutics Inc., a leader in the development of innovative autologous cellular therapies for highly debilitating neurodegenerative diseases, today announced publication of "NurOwn Phase 2 Randomized Clinical Trial in ALS: Safety, Clinical and BioMarker Results," in the international, peer-reviewed journal Neurology.

20 Nov 2019

Researchers uncover novel pathogenic mechanism in Huntington’s disease

Researchers from the Institute of Neurosciences of the University of Barcelona and the August Pi i Sunyer Biomedical Research Institute described a mechanism, the increase of proteinaceous synthesis, which takes part in the degeneration of the type of neurons that are affected in Huntington's disease, a genetic neurodegenerative disease.

20 Nov 2019

Applying a Proteomics-based Approach to the Clinic

Matthias Mann explains why applying proteomics-based technologies such as timsTOF could accelerate the diagnosis and prediction of human disease.

From Bruker Daltonics 20 Nov 2019

Proteomics & DIA Mass Spectrometry in Neurodegenerative Disease Research

News-Medical Life Sciences spoke to Nicholas Dupuis from Biognosys about proteomics & DIA mass spectrometry in neurodegenerative disease research.

From Biognosys 19 Nov 2019

Mining 'darkest' parts of the genome in cancer cells yields gold

Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.

15 Nov 2019

New insights into how immune system and inflammation play a role in PD

Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research.

14 Nov 2019

Promising method to identify aggressive breast cancers that will respond to immunotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers have discovered a promising method to identify aggressive breast cancer tumors that will respond to drugs that unleash the immune system against cancer.

14 Nov 2019

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

After decades of little or no progress, biomedical researchers are finally making some headway at detecting and treating sepsis, a deadly medical complication that sends a surge of pathogenic infection through the body and remains a major public health problem.

14 Nov 2019

Study shows potential of phage therapy to treat alcoholic liver disease

Bacteriophages (phages) are viruses that specifically destroy bacteria. In the early 20th century, researchers experimented with phages as a potential method for treating bacterial infections.

13 Nov 2019

New biomarker discovered in cancer stem cells

In the world of cancer biology, not all biomarkers are created equal. These molecules that alert doctors that an abnormal process may be underway can appear as an array of aberrant proteins, such as hormones, enzymes or signaling molecules, and vary from patient to patient. Because they are a mixed bag, no one drug exists to attack them.

13 Nov 2019

Researchers take major step towards developing a viable vaccine for malaria

Researchers have narrowed down the malaria proteins and disease-fighting antibodies that could be used to develop a vaccine against the most severe forms of malaria.

13 Nov 2019

Scientists move closer towards developing an effective malaria vaccine

Scientists have taken another big step forward towards developing a vaccine that’s effective against the most severe forms of malaria.

13 Nov 2019

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

An autoimmune attack on uninfected red blood cells likely contributes to anaemia - a shortage of red blood cells - in people with malaria, according to a new study published in eLife.

12 Nov 2019

Contraceptive drug effective in preventing and regressing cervical cancer in mice

A new study in The American Journal of Pathology, published by Elsevier, reports that medroxyprogesterone acetate (MPA), the active ingredient in the common contraceptive injection Depo-Provera, was effective in preventing the development of cervical cancer in mice with precancerous lesions.

12 Nov 2019

Retinal hyperspectral imaging shows promise for early Alzheimer's disease detection

Alzheimer's disease is the leading cause of dementia in the U.S., with approximately 5.4 million currently affected and an estimated 16 million by 2050.

11 Nov 2019

Australia has limited capacity to move future Alzheimer's therapy into wide clinical use

As in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from approval into wide clinical use, which could leave thousands of older people without access to transformative care if such a breakthrough occurs, according to a new study by RAND Australia.

11 Nov 2019

New blood test for protein biomarkers could identify people in need of treatment

Without occasionally looking under the hood, it's difficult to predict whether expensive car repairs lie ahead. In a similar way, preventive cardiologists are looking for ways to detect early stage heart disease in people who aren't currently in treatment.

11 Nov 2019

Biomarker News and Research

Further Reading

Study reveals how adults exposed to alcohol go on to develop compulsive drinking behaviors

University of Sheffield receives Queen's Anniversary Prize for innovation in neuroscience

Sphingolipids associated with heart disease in African Americans with lupus

BrainStorm publishes NurOwn ALS Phase 2 randomized clinical trial results in Neurology

Researchers uncover novel pathogenic mechanism in Huntington’s disease

Applying a Proteomics-based Approach to the Clinic

Proteomics & DIA Mass Spectrometry in Neurodegenerative Disease Research

Mining 'darkest' parts of the genome in cancer cells yields gold

New insights into how immune system and inflammation play a role in PD

Promising method to identify aggressive breast cancers that will respond to immunotherapy

Researchers develop, test new blood assay that predicts patients at risk of death from sepsis

Study shows potential of phage therapy to treat alcoholic liver disease

New biomarker discovered in cancer stem cells

Researchers take major step towards developing a viable vaccine for malaria

Scientists move closer towards developing an effective malaria vaccine

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

Contraceptive drug effective in preventing and regressing cervical cancer in mice

Retinal hyperspectral imaging shows promise for early Alzheimer's disease detection

Australia has limited capacity to move future Alzheimer's therapy into wide clinical use

New blood test for protein biomarkers could identify people in need of treatment

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo