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EchoBack CAR T-cells could be a game changer in cancer immunotherapy

Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors - a smart fighter that destroys cancer cells for days without tiring.

2 Apr 2025

How your skin’s microbes shape immunity, inflammation, and chronic skin disease

Skin microbes do more than coexist—they shape immune responses, repair tissue, and influence gene expression across your lifespan. This review explains how disruptions in this microbiome-immune dialogue can lead to eczema, psoriasis, or acne.

2 Apr 2025

FGFR2 identified as key driver in KRAS-mutated pancreatic cancer progression

Precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated PDAC development in mice.

2 Apr 2025

Breakthrough research reveals gut-eye connection in vision loss

Inherited retinal degeneration (IRD) encompasses various disorders characterized by progressive loss of retinal photoreceptor cells, ultimately leading to vision loss and blindness.

2 Apr 2025

Breakthrough study links NSD2 gene to plasma cell identity in myeloma

A new research paper was published in Oncotarget, Volume 16, on March 21, 2025, titled "NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma."

2 Apr 2025

New class of antibiotic selectively targets gonorrhea bacterium

Researchers from the universities in Konstanz and Vienna discover a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhea.

2 Apr 2025

Understanding the phases and treatment options for Peyronie’s disease

The review article titled"Current insights and future directions in Peyronie's disease management: A narrative review", was published on November 12, 2024 in UroPrecision.

2 Apr 2025

AI predicts bacterial resistance to antibiotics with high accuracy

An AI model trained on large amounts of genetic data can predict whether bacteria will become antibiotic-resistant.

2 Apr 2025

Weekend exercise can offer the same health benefits as daily workouts

Being physically active for one to two days a week, often called a "weekend warrior," may provide comparable health and life-prolonging benefits as smaller doses of daily physical activity if the physical effort is moderate to vigorous and totals 150 minutes a week in line with recommended guidelines for weekly physical activity, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

2 Apr 2025

New study explores link between gut microbiome and autism spectrum disorder

Researchers evaluate the relationship between the gut microbiome and autism spectrum disorder.

2 Apr 2025

Scientists make breakthrough in understanding the causes of spina bifida

Scientists at Rady Children's Institute for Genomic Medicine, and the Department of Neurosciences and Pediatrics at the University of California, San Diego, have made a significant breakthrough in understanding the causes of spina bifida, a serious birth defect affecting thousands of newborns each year.

1 Apr 2025

Comprehensive AAV delivery map aids in advancing gene therapy

Gene therapy, a technique that is revolutionizing the treatment of multiple genetic conditions, including eye and muscle diseases and blood disorders, requires efficient and specific delivery of the genetic material to the tissue and cell type of interest.

1 Apr 2025

Novel ARPC1B mutation identified in a patient with recurrent eosinophilia

Immunodeficiency disorders linked to cytoskeleton defects are rare and complex, often presenting with diverse clinical features.

1 Apr 2025

Research highlights rising risk of human-to-human mpox transmission

Mpox has the potential to become a significant global health threat if taken too lightly, according to scientists at the University of Surrey.

1 Apr 2025

New approach speeds up personalized cancer treatment for young patients

A pan-Canadian team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and analyzing their proteins.

1 Apr 2025

Study shows women can hear better than men

An international team of scientists has found that biological sex is the leading factor explaining differences in hearing sensitivity, with women having significantly more sensitive hearing than men.

From University of Bath 1 Apr 2025

Mayo Clinic launches study to investigate rapidly progressive dementia in Alzheimer's

Most patients with Alzheimer's disease and Alzheimer's Disease Related Dementias (ADRD) experience the gradual onset and progression of cognitive symptoms, leading to decline over years or decades.

1 Apr 2025

ALL ALS Consortium creates a central information hub to accelerate ALS research

The Access for All in ALS (ALL ALS) Consortium announced the launch of its official website, creating a central hub for information about its initiatives and clinical research studies. ALL-ALS.org is designed to inform and engage researchers, clinicians, and current and prospective study participants.

31 Mar 2025

Defibrillators and CPR cut marathon cardiac deaths in half, study shows

Researchers found that while the rate of cardiac arrests during U.S. marathons and half-marathons remained stable from 2010 to 2023, the likelihood of death from these events dropped by nearly half—thanks to faster emergency response and widespread use of defibrillators.

31 Mar 2025