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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

Exploring trends in SARS-CoV-2 RNA concentrations in wastewater

In a new study, researchers characterized trends of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA levels in wastewater.

1 Nov 2022

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New research discussed the structure and life cycle of respiratory syncytial virus (RSV), the current research on the treatment and prevention of RSV infections, and the advancements in RSV mRNA vaccine technology after the surge in vaccine research during the COVID-19 pandemic.

1 Nov 2022

Exploring viral loads of SARS-CoV-2 Omicron BA.5 and BA.2 sublineages

In a new study, researchers compared the viral loads of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.5 and BA.2 sublineages.

1 Nov 2022

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Researchers performed single-nucleus RNA sequencing (snRNA-seq) and spatial transcriptomic profiling of livers from deceased coronavirus disease 2019 (COVID-19) patients.

1 Nov 2022

Johns Hopkins researchers uncover a possible target to treat sleep apnea

In a new study with obese mice, Johns Hopkins Medicine researchers say they have added to evidence that specialized channel proteins are possible therapeutic targets for sleep apnea and similar abnormally slow breathing disorders in obese people.

31 Oct 2022

Favorable outcomes of infants born after maternal COVID-19 during pregnancy

Researchers assess the outcomes of children born to mothers infected during pregnancy with SARS-CoV-2.

30 Oct 2022

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

RNA, the molecule that gave rise to life, has been shown to be essential for repairing human genetic material and preventing mutations that might lead to developing cancer.

28 Oct 2022

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

Researchers evaluated the concurrent colonization of fungi in the nasopharynx of severe COVID-19 patients.

28 Oct 2022

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.

28 Oct 2022

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Johns Hopkins Medicine researchers say they have successfully used a cell's natural process for making proteins to "slide" genetic instructions into a cell and produce critical proteins missing from those cells.

28 Oct 2022

Ancient viral DNA in human genomes protects cells against present-day viruses

Viral DNA in human genomes, embedded there from ancient infections, serve as antivirals that protect human cells against certain present-day viruses, according to new research.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy.

27 Oct 2022

RNA News and Research

Further Reading

New control system could be used to finely tune the production of useful proteins

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Exploring trends in SARS-CoV-2 RNA concentrations in wastewater

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Exploring viral loads of SARS-CoV-2 Omicron BA.5 and BA.2 sublineages

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Johns Hopkins researchers uncover a possible target to treat sleep apnea

Favorable outcomes of infants born after maternal COVID-19 during pregnancy

Researchers propose origin-of-life molecule as therapeutic target for tailored cancer therapies

Association of COVID-19 severity with nasopharyngeal fungal colonization and interleukin-17 induction

New breakthrough in understanding how deletion of certain genes can lead to cancer growth

Proof-of-principle study: Novel tool advances potential way to deliver gene therapy

Ancient viral DNA in human genomes protects cells against present-day viruses

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers find a switch to regulate the diabetes-causing gene

Increased Gibbs energy of binding indicates greater infectivity of SARS-CoV-2 BA.2.75

Research reveals molecular pathways of aggressive cribriform prostate cancer

What is the efficacy of RT-PCR assays for detection of SARS-CoV-2 in human semen?

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

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