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Endovascular stroke therapy should be limited to use within clinical trials, say physicians

Devices snaked into the brain artery of a patient experiencing a stroke that either snatch and remove the offending clot or pump a dissolving drug into the blockage should primarily be used within a clinical trial setting, say a team of vascular neurologists at Mayo Clinic in Florida.

30 May 2013

Cedars-Sinai team awarded grant to study cardiac stem cell treatment for Duchenne muscular dystrophy

Newport Beach-based nonprofit Coalition Duchenne has awarded a $150,000 grant to a Cedars-Sinai Heart Institute team investigating whether an experimental cardiac stem cell treatment could be used to treat Duchenne muscular dystrophy patients who have developed heart disease.

30 May 2013

Radiotherapy: First choice treatment for low-grade glioma

In a large, international, randomized trial, initial radiotherapy was compared to temozolomide chemotherapy. A statistically significant difference between the two treatment strategies was not observed for progression-free survival, although radiotherapy was numerically favored. However, molecular tumor characterization may allow the treatment approach to be personalized and one or the other treatment modality to be selected.

30 May 2013

New hope for children with multi-system LCH

A new international study finds that prolonged, intense initial treatment in children with multi-system Langerhans cell histiocytosis can achieve survival rates as high as 84 percent-a full 15 percent improvement over the previous clinical trial in this series.

30 May 2013

Gene therapy techniques show promise in promoting growth of skin, bone and other tissues

Experimental genetic techniques may one day provide plastic and reconstructive surgeons with an invaluable tool-the ability to promote growth of the patient's own tissues for reconstructive surgery.

30 May 2013

Targacept initiates TC-5214 Phase 2b clinical study in patients with OAB

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced the initiation of a Phase 2b clinical study of TC-5214 as a treatment for overactive bladder.

29 May 2013

Atopix awarded grant to pursue development of OC459 for atopic dermatitis

Atopix Therapeutics Ltd, a biopharmaceutical company developing a novel class of anti-allergic medicines, has been awarded a £1.7 million grant from the UK Biomedical Catalyst fund to pursue development of OC459 in the treatment of moderate-to-severe atopic dermatitis (a form of eczema).

29 May 2013

Viewpoints: 'Good news' on Calif. insurance rates; Battle against dementia needs stronger efforts; Dental care for the disabled

The Affordable Care Act, a k a Obamacare, goes fully into effect at the beginning of next year, and predictions of disaster are being heard far and wide. ... No doubt there will be problems, as there are with any large new government initiative, and in this case, we have the added complication that many Republican governors and legislators are doing all they can to sabotage reform. Yet important new evidence - especially from California, the law's most important test case - suggests that the real Obamacare shock will be one of unexpected success (Paul Krugman, 5/26).

29 May 2013

Survival rates increased among patients who received blood stem cell transplants: Study

Survival rates have increased significantly among patients who received blood stem cell transplants from both related and unrelated donors, according to a study published in the Journal of Clinical Oncology today.

29 May 2013

$2 million grant to provide instrumentation, core facilities devoted to synthetic biology

The Roy J. Carver Charitable Trust has awarded a $2 million grant to the Institute for Genomic Biology at the University of Illinois at Urbana-Champaign. Under the leadership of Principal Investigator Dr. Huimin Zhao and co-Principal Investigator Dr. Christopher Rao, the grant will be disbursed over two years to provide instrumentation and core facilities for a new research theme devoted to the new scientific subdiscipline of synthetic biology.

29 May 2013

Researchers to examine effectiveness of antibiotic therapy to treat appendicitis in children

In the first study of its kind in the United States, researchers at Nationwide Children's Hospital will examine the effectiveness of antibiotic therapy alone to treat appendicitis in children, research that could allow patients to avoid a surgery many may not need.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Johns Hopkins scientists report that a 10-minute test for "frailty" first designed to predict whether the elderly can withstand surgery and other physical stress could be useful in assessing the increased risk of death and frequent hospitalization among kidney dialysis patients of any age.

29 May 2013

LA BioMed researchers recognized for training next generation of physicians

Carol Berkowitz, MD, and Mallory D. Witt, MD, lead researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, received the Serge & Yvette Dadone Clinical Teaching Award in Honor of Saleh Salehmoghaddam, M.D., a peer-reviewed recognition of their "outstanding dedication, innovation, and sustained excellence in clinical and classroom teaching," according to the David Geffen School of Medicine at UCLA, which presented the awards.

29 May 2013

Crittenton researchers receive grant to study trauma treatment in children

Crittenton Children's Center has received a two-year, $10,000 grant from the Eye Movement Desensitization and Reprocessing Research Foundation to conduct a first of its kind study addressing trauma in children.

29 May 2013

Research data on AMPYRA Extended Release Tablets to be presented at CMSC and ACTRIMS meeting

Acorda Therapeutics, Inc. will present new research data on AMPYRA (dalfampridine) Extended Release Tablets, 10 mg at the 5th Cooperative Meeting of the Consortium of Multiple Sclerosis Centers and Americas Committee for Treatment and Research in Multiple Sclerosis, being held in Orlando, FL, May 29 - June 1.

28 May 2013

Asfotase alfa gets Breakthrough Therapy designation from FDA for treatment of patients with HPP

Alexion Pharma International Sàrl, a subsidiary of Alexion Pharmaceuticals, Inc., today announced that the U.S. Food and Drug Administration has granted Breakthrough Therapy designation to asfotase alfa for the treatment of patients with hypophosphatasia (HPP) whose first signs or symptoms occurred prior to 18 years of age, including perinatal-, infantile-, and juvenile-onset forms of the disease.

28 May 2013

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Scientists at UC Irvine reported this week that a synthetic compound ShK-186, originally derived from a sea anemone toxin, has been found to enhance metabolic activity and shows potential as a treatment for obesity and insulin resistance.

28 May 2013

Omthera to be acquired by AstraZeneca

AstraZeneca today announced that it has entered into a definitive agreement to acquire Omthera Pharmaceuticals, a specialty pharmaceutical company based in Princeton, New Jersey, focused on the development and commercialization of new therapies for abnormal levels of lipids in the blood, referred to as dyslipidemia.

28 May 2013

Human foetal stem cell therapy improves structural integrity of the spine

Human foetal stem cell grafts improve both motor and sensory functions in rats suffering from a spinal cord injury, according to research published this week in BioMed Central's open access journal Stem Cell Research and Therapy.

28 May 2013

Therapy News and Research

Endovascular stroke therapy should be limited to use within clinical trials, say physicians

Cedars-Sinai team awarded grant to study cardiac stem cell treatment for Duchenne muscular dystrophy

Radiotherapy: First choice treatment for low-grade glioma

New hope for children with multi-system LCH

Gene therapy techniques show promise in promoting growth of skin, bone and other tissues

Targacept initiates TC-5214 Phase 2b clinical study in patients with OAB

Atopix awarded grant to pursue development of OC459 for atopic dermatitis

Viewpoints: 'Good news' on Calif. insurance rates; Battle against dementia needs stronger efforts; Dental care for the disabled

Survival rates increased among patients who received blood stem cell transplants: Study

$2 million grant to provide instrumentation, core facilities devoted to synthetic biology

Researchers to examine effectiveness of antibiotic therapy to treat appendicitis in children

Transplantation of human stem cells improves muscle function in rats used to model ALS

New test to predict increased risk of death, hospitalization among kidney dialysis patients

LA BioMed researchers recognized for training next generation of physicians

Crittenton researchers receive grant to study trauma treatment in children

Research data on AMPYRA Extended Release Tablets to be presented at CMSC and ACTRIMS meeting

Asfotase alfa gets Breakthrough Therapy designation from FDA for treatment of patients with HPP

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Omthera to be acquired by AstraZeneca

Human foetal stem cell therapy improves structural integrity of the spine

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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