Therapy News and Research

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Data on side effects of fidaxomicin not analysed appropriately

The antibiotic fidaxomicin (trade name: Dificlir) has been approved in Germany since December 2011 for the treatment of adults who have diarrhoea caused by Clostridium difficile.

3 Jul 2013

Home-based exercise intervention improves walking performance, physical activity in PAD patients

In a trial that included nearly 200 participants with peripheral artery disease, a home-based exercise intervention with a group-mediated cognitive behavioral intervention component improved walking performance and physical activity in patients with PAD, according to a study in the July 3 issue of JAMA.

3 Jul 2013

LARIAT procedure prevents stroke in patients who are unable to tolerate blood thinners

Jersey Shore University Medical Center is one of only a handful of hospitals in the country offering the recent FDA-approved LARIAT Suture Delivery Device procedure. Electrophysiologists and interventional cardiologists perform this innovative procedure to help prevent stroke in patients who suffer from atrial fibrillation and are unable to take blood thinners.

3 Jul 2013

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

Yale Cancer Center scientists, together with colleagues at the Denver Police Crime Lab and the University of Colorado, have found evidence that a human metastatic tumor can arise when a leukocyte (white blood cell) and a cancer cell fuse to form a genetic hybrid.

3 Jul 2013

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Scientists found genetic variations that could be used to identify women who are most likely to benefit from a certain type of breast cancer prevention drug—and who should avoid it.

3 Jul 2013

Biogen, Sobi present new findings from Phase 3 trial of ALPROLIX at XXIV ISTH Congress

Biogen Idec and Swedish Orphan Biovitrum AB (publ) today presented new findings for their long-lasting recombinant factor IX candidate ALPROLIX for hemophilia B at the XXIV International Society on Thrombosis and Haemostasis Congress in Amsterdam, The Netherlands.

3 Jul 2013

Pitt researchers propose mathematical model that examines multiple walking patterns in older adults

Older adults diagnosed with brain disorders such as Parkinson's disease often feel a loss of independence because of their lack of mobility and difficulty walking.

3 Jul 2013

Abiraterone can prolong overall survival and delay severe pain in prostate cancer patients

Abiraterone acetate (abiraterone for short, trade name: Zytiga) has been approved in Germany since December 2012 for men with metastatic prostate cancer that is not responsive to hormone blockade, who only have mild symptoms or so far none at all, and in whom chemotherapy is not yet indicated.

3 Jul 2013

Gene therapy developed by UAB cures pediatric Sanfilippo Syndrome A in animal models

A single session of a gene therapy developed by the Universitat Autònoma de Barcelona (UAB) cures Sanfilippo Syndrome A in animal models. This syndrome is a neurodegenerative disease that affects between 1 and 9 out of every 100,000 children, and causes the death of the child on reaching adolescence.

3 Jul 2013

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress response by increasing numerous antioxidants and pollutant-detoxifying genes to protect the lungs from variety of air pollutants such as diesel exhaust and cigarette smoke.

3 Jul 2013

Curcumin may provide lasting protection against lung damage in premature infants

Turmeric, a key ingredient in spicy curry dishes, has long been known to have medicinal values. Now new research finds a substance in turmeric, curcumin, may provide lasting protection against potentially deadly lung damage in premature infants.

3 Jul 2013

Devon Medical gets ANVISA certification for extriCARE 2400 NPWT system

Devon Medical, a global medical device manufacturer, designer, and distributor, announced today that it has received medical device registration and approval from the Brazilian National Health Surveillance Agency (ANVISA - Agência Nacional de Vigilância Sanitária) for its extriCARE 2400 Negative Pressure Wound Therapy pump.

2 Jul 2013

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that the TransATAC clinical validation study for its Prosigna Breast Cancer Prognostic Gene Signature Assay, which is based on the PAM50 gene signature, was published in the Journal of Clinical Oncology.

From NanoString Technologies 2 Jul 2013

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

ARIAD Pharmaceuticals, Inc. today announced that the European Commission has granted a marketing authorization for Iclusig (ponatinib) as an orphan medicinal product for two indications.

2 Jul 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Researchers at UCLA's Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells from the bone marrow of patients with sickle cell disease to treat the disease.

2 Jul 2013

UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

Case Western Reserve University has signed an exclusive worldwide licensing agreement granting University Hospitals Case Medical Center rights to a series of diagnostic tests to determine drug resistance and co-receptor tropism in human immunodeficiency virus.

2 Jul 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

The Fondation Leducq in Paris, France, dedicated to improving human health through international efforts to combat cardiovascular disease, awarded a $6 million grant award to a new global research network of cardiovascular scientists which includes three researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

2 Jul 2013

Mixed results for acupuncture in improving IVF rates

Acupuncture, when used as a complementary or adjuvant therapy for in vitro fertilization (IVF), may be beneficial depending on the baseline pregnancy rates of a fertility clinic, according to research from the University of Maryland School of Medicine. The analysis from the University of Maryland Center for Integrative Medicine is published in the June 27 online edition of the journal Human Reproduction Update.

2 Jul 2013

Study evaluates implementation of out-of hospital stroke policy in some Chicago hospitals

Implementing an out-of hospital stroke policy in some Chicago hospitals was associated with significant improvements in emergency medical services use and increased intravenous tissue plasminogen activator use at primary stroke centers, according to a study published by JAMA Neurology.

2 Jul 2013

UNC scientists use GEMMs to develop biomarkers for molecular subtypes of human breast cancer

It's a GEMM of a system. Genetically engineered mouse models that is. Using them allows scientists to study cancer in a way that more naturally mimics how human tumors exist within the complex environment of the body.

2 Jul 2013

Therapy News and Research

Data on side effects of fidaxomicin not analysed appropriately

Home-based exercise intervention improves walking performance, physical activity in PAD patients

LARIAT procedure prevents stroke in patients who are unable to tolerate blood thinners

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

Genetic variations can identify women who are likely to benefit from breast cancer prevention drug

Biogen, Sobi present new findings from Phase 3 trial of ALPROLIX at XXIV ISTH Congress

Pitt researchers propose mathematical model that examines multiple walking patterns in older adults

Abiraterone can prolong overall survival and delay severe pain in prostate cancer patients

Gene therapy developed by UAB cures pediatric Sanfilippo Syndrome A in animal models

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Curcumin may provide lasting protection against lung damage in premature infants

Devon Medical gets ANVISA certification for extriCARE 2400 NPWT system

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

UCLA researchers introduce gene therapy technique to treat sickle cell disease

UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

Mixed results for acupuncture in improving IVF rates

Study evaluates implementation of out-of hospital stroke policy in some Chicago hospitals

UNC scientists use GEMMs to develop biomarkers for molecular subtypes of human breast cancer

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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