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Adults formerly treated for childhood cancer have chronic health problems

In an analysis that included more than 1,700 adult survivors of childhood cancer, researchers found a very high percentage of survivors with 1 or more chronic health conditions, with an estimated cumulative prevalence of any chronic health condition of 95 percent at age 45 years, according to a study in the June 12 issue of JAMA.

14 Jun 2013

Gene variants may predict which women are most likely to benefit from breast cancer therapy

In women at high risk for breast cancer, a long-term drug treatment can cut the risk of developing the disease in half. Researchers supported by the National Institutes of Health have now identified two gene variants that may predict which women are most likely to benefit from this therapy—and which should avoid it.

14 Jun 2013

Study demonstrates efficacy of canakinumab at tapering corticosteroid use in patients with SJIA

Study findings first presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate the efficacy of canakinumab at tapering corticosteroid (CS) use in patients with SJIA.

14 Jun 2013

New drug target may prevent consequences of ACL tear in athletes

Striking the likes of Chicago Bulls' Derrick Rose, L.A. Lakers' Kobe Bryant and Detroit Tigers' Victor Martinez, tears in the anterior cruciate ligament (ACL) are one of the most rampant and serious knee injuries among athletes.

14 Jun 2013

Genetic variations may help predict breast cancer risk in women who receive preventive therapy

Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. The study is published in the journal Cancer Discovery.

14 Jun 2013

IPC to distribute AP's Promescent in US for treatment of premature ejaculation

The Independent Pharmacy Cooperative and Absorption Pharmaceuticals have signed a distribution agreement whereby IPC will make AP's topical treatment for premature ejaculation, Promescent, available to its 4,500+ member pharmacies throughout the United States.

14 Jun 2013

Overweight, obese ERA patients require twice as much drug therapy to achieve successful remission

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, shows that overweight and obese patients are less likely to achieve successful remission in early rheumatoid arthritis compared to those of normal weight.

14 Jun 2013

Data demonstrate benefits of nurse-led programme on patient self-management of RA

Data first presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism demonstrate the benefits of a nurse-led programme on patient self-management and the management of rheumatoid arthritis co-morbidities.

14 Jun 2013

Findings provide basis for reinvigoration of research efforts in breast cancer prevention

Genetic variations, known as single nucleotide polymorphisms, in or near the genes ZNF423 and CTSO were associated with breast cancer risk among women who underwent prevention therapy with tamoxifen and raloxifene, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

14 Jun 2013

Study provides new insight into how pyrazinamide works

Pyrazinamide (PZA)-a frontline tuberculosis drug-kills dormant persister bacteria and plays a critical role in shortening TB therapy. PZA is used for treating both drug susceptible and multi-drug resistant TB but resistance to PZA occurs frequently and can compromise treatment.

14 Jun 2013

Penn Medicine researchers identify key molecular player in recurrent breast cancer

According to the American Cancer Society, nearly 40,000 women in the United States will succumb to breast cancer this year. Most of these women will die not from the primary tumor but rather tumor recurrence - the reappearance of the disease following treatment.

14 Jun 2013

Mount Sinai researchers produce cells that resemble hematopoietic stem cells

By transferring four genes into mouse fibroblast cells, researchers at the Icahn School of Medicine at Mount Sinai have produced cells that resemble hematopoietic stem cells, which produce millions of new blood cells in the human body every day.

14 Jun 2013

New study tests vestibular prosthesis to help restore balance for people with Meniere's disease

Many disorders of the inner hear which affect both hearing and balance can be hugely debilitating and are currently largely incurable. Cochlear implants have been used for many years to replace lost hearing resulting from inner ear damage.

14 Jun 2013

NACC recommendations address established pain therapies and preview potential future advances

Recommendations of the Neuromodulation Appropriateness Consensus Committee (NACC), announced at the 11th World Congress of the International Neuromodulation Society (INS), address established therapies and preview emerging and potential future advances.

13 Jun 2013

Study: Tocilizumab is effective in children with juvenile idiopathic arthritis

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism shows that tocilizumab is efficacious and leads to a sustained clinically meaningful improvement in children with polyarticular Juvenile Idiopathic Arthritis (pcJIA).

13 Jun 2013

Ustekinumab doses improve signs and symptoms of PsA with favourable safety profiles

New PSUMMIT 2 data first presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, further demonstrate the efficacy of ustekinumab in Psoriatic Arthritis (PsA).

13 Jun 2013

NBMC signs contract for Unibased's ForSite2020 solutions

Unibased Systems Architecture, Inc. announced today that North Bend Medical Center, Inc., located in Coos Bay, OR, has signed an agreement for its market-leading surgery management solution, ForSite2020 periOperative Resource Management System, aimed at improving workflow and productivity as well as providing efficient resource management to reduce costs and effectively manage inventory.

13 Jun 2013

Combination of Pressure Right and antiemetic drug therapy can reduce PONV with no adverse effects

From a clinical-based perspective, postoperative nausea and vomiting (PONV) can be characterized as an unmet global phenomenon in which anesthesia practitioners and PACU nurses worldwide are seeking more efficient clinical strategies for preventing PONV.

13 Jun 2013

Apremilast continues to demonstrate meaningful clinical responses in patients with psoriatic arthritis

New data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism show that apremilast administered to patients with psoriatic arthritis continues to demonstrate meaningful clinical responses beyond 24 weeks.

13 Jun 2013

Study demonstrates efficacy of ARASHI method at evaluating radiographic joint damage in RA

A new study presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrates the efficacy of the ARASHI method at evaluating radiographic (X-ray) joint damage in RA.

13 Jun 2013

Therapy News and Research

Adults formerly treated for childhood cancer have chronic health problems

Gene variants may predict which women are most likely to benefit from breast cancer therapy

Study demonstrates efficacy of canakinumab at tapering corticosteroid use in patients with SJIA

New drug target may prevent consequences of ACL tear in athletes

Genetic variations may help predict breast cancer risk in women who receive preventive therapy

IPC to distribute AP's Promescent in US for treatment of premature ejaculation

Overweight, obese ERA patients require twice as much drug therapy to achieve successful remission

Data demonstrate benefits of nurse-led programme on patient self-management of RA

Findings provide basis for reinvigoration of research efforts in breast cancer prevention

Study provides new insight into how pyrazinamide works

Penn Medicine researchers identify key molecular player in recurrent breast cancer

Mount Sinai researchers produce cells that resemble hematopoietic stem cells

New study tests vestibular prosthesis to help restore balance for people with Meniere's disease

NACC recommendations address established pain therapies and preview potential future advances

Study: Tocilizumab is effective in children with juvenile idiopathic arthritis

Ustekinumab doses improve signs and symptoms of PsA with favourable safety profiles

NBMC signs contract for Unibased's ForSite2020 solutions

Combination of Pressure Right and antiemetic drug therapy can reduce PONV with no adverse effects

Apremilast continues to demonstrate meaningful clinical responses in patients with psoriatic arthritis

Study demonstrates efficacy of ARASHI method at evaluating radiographic joint damage in RA

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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