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TSRI scientists find emotion-related brain region plays major role in sustaining cocaine addiction

Scientists at The Scripps Research Institute (TSRI) have found evidence that an emotion-related brain region called the central amygdala—whose activity promotes feelings of malaise and unhappiness—plays a major role in sustaining cocaine addiction.

13 Jun 2013

Using Swiss ball improves walking performance and muscle strength in AS patients

A new study presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrates that progressive muscle strengthening using a Swiss ball is effective in improving muscle strength and walking performance in patients with Ankylosing Spondylitis (AS).

13 Jun 2013

Society of Interventional Radiology releases Updates in Interventional Radiology 2013

The Society of Interventional Radiology announces the release of "Updates in Interventional Radiology 2013," a concise reference of the current literature most relevant to the specialty.

13 Jun 2013

PTSD patients with Met-66 allele of BDNF show poorer response to exposure therapy

There is growing evidence that a gene variant that reduces the plasticity of the nervous system also modulates responses to treatments for mood and anxiety disorders. In this case, patients with posttraumatic stress disorder, or PTSD, with a less functional variant of the gene coding for brain-derived neurotrophic factor, responded less well to exposure therapy.

13 Jun 2013

WHO issues interim policy guidance on inclusion of bedaquiline to treat adults with MDR-TB

WHO estimates that up to half a million new cases of multidrug-resistant tuberculosis occur worldwide, each year. Current treatment regimens for MDR-TB present many challenges: treatment lasts 20 months or more, requiring daily administration of drugs that are more toxic, less effective, and far more expensive than those used to treat drug-susceptible TB.

13 Jun 2013

Constella® (linaclotide), for the symptomatic treatment of Irritable Bowel Syndrome with Constipation (IBS-C), is now available in Germany, UK and Nordic countries

Almirall, S.A. (ALM:MC) and Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) announced the launch of Constella® (linaclotide 290mcg capsules once daily), the first approved prescription therapy in a new class of treatments for adults suffering from moderate to severe IBS-C,(1) in Europe. Constella® is now available in Germany, the UK and Nordic countries and is expected to be launched in several other European countries in 2013.

13 Jun 2013

Investigational all-oral interferon-free combination from Boehringer Ingelheim achieves 95% viral cure rates in genotype-1b hepatitis C patients

New data from Boehringer Ingelheim’s interferon-free SOUND-C3 study were presented during the APASL Liver Week in Singapore. The Phase IIb study investigated the efficacy and safety of faldaprevir+ and deleobuvir+ (BI 207127) plus ribavirin in treatment-naïve patients with genotype-1b (GT-1b) hepatitis C virus (HCV),1 one of the most common types of HCV globally.2

13 Jun 2013

One-third of RA patients discontinue therapy within the first year of treatment

Data presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, show that up to one-third of rheumatoid arthritis patients discontinue or change therapy within the first year of treatment.

13 Jun 2013

Study: Depression indicators are stronger predictors of work disability in early arthritis

Data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that indicators of depression are stronger predictors of work disability in early arthritis than disease activity or response to therapy.

13 Jun 2013

State highlights: Ala. abortion law challenged in court; NYC officials try again on soda restrictions

As the protests have grown, so has the list of causes. At the center is a package of changes to voting rules and a tax reform plan working its way through the legislature that would reduce individual and corporate income taxes and expand the sales tax. Protesters have also rallied against the expansion of school vouchers, cuts to unemployment benefits, the repeal of the Racial Justice Act, efforts to allow hydraulic fracturing and the state's refusal to expand Medicaid benefits as part of President Obama's health care plan (Severson, 6/11).

13 Jun 2013

New collaboration to advance cancer immunotherapy research

The Cancer Research Institute, the Ludwig Institute for Cancer Research and Immune Design, a biotech company focused on immune-based therapies for cancer and other human diseases, today announced that they have signed a collaboration agreement to advance cancer immunotherapy research.

13 Jun 2013

Black women with breast cancer experience treatment delays, new study finds

Black women with breast cancer are more likely than Hispanic or white women to experience delays in the initiation of chemotherapy or radiation after surgery, finds a new study in Health Services Research.

13 Jun 2013

Radionuclide drug treatment planning goes to next level with 3-D patient models

External beam radiation treatment has long been manipulated into the unique shape of patients' tumors for personalized cancer care. Technology providing a means of patient-specific radionuclide drug therapies has not been standardized, as it has been limited to software that requires oncologists to manually define the areas of tumors.

13 Jun 2013

Calif. budget agreement seeks balance, but leaves off some health care items

A budget agreement in California between lawmakers and Governor Jerry Brown seeks to strike a balance between spending restraint and providing more health care for the needy, the Los Angeles Times reports. But the agreement lacks several health care line items lawmakers bandied about in recent weeks -- including repeal of a 10 percent provider cut to Medi-Cal.

13 Jun 2013

Effective method to restore sight to patients with blinding diseases

Researchers at the University of California, Berkeley, have developed an easier and more effective method for inserting genes into eye cells that could greatly expand gene therapy to help restore sight to patients with blinding diseases ranging from inherited defects like retinitis pigmentosa to degenerative illnesses of old age, such as macular degeneration

13 Jun 2013

Diabetes Calculator for Kids: An electronic tool that helps parents manage their child's diabetes

Nationwide Children's Hospital recently developed an online resource to help parents manage their child's diabetes more effectively and care for their health at home.

13 Jun 2013

3D motion-tracked PET imaging uses MR micro-coils to reduce movement-related imaging artifacts

One of the biggest hurdles of hybrid positron emission tomography and magnetic resonance imaging is the prevalence of motion artifacts-blurring and ghostly visual anomalies caused by patient motion on the table during imaging.

13 Jun 2013

New study shows treatment with brodalumab demonstrates clinical response in subjects with PsA

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, shows that treatment with brodalumab demonstrates significant clinical response and an acceptable safety profile in subjects with psoriatic arthritis.

13 Jun 2013

Combination of cytoreductive surgery and HIPEC may reduce mortality in abdominal cancers patients

Researchers at Roswell Park Cancer Institute (RPCI) have determined that cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CS/HIPEC), a complex procedure to treat advanced abdominal cancers, can be done safely, and may be an effective therapy for select patients. Study results are published in the June issue of Cancer Medicine.

12 Jun 2013

Loyola University surgeon uses electrical stimulation as part of surgical technique to treat Bell's palsy

A Loyola University Medical Center surgeon is using electrical stimulation as part of an advanced surgical technique to treat Bell's palsy. Bell's palsy is a condition that causes paralysis on one side of a patient's face.

12 Jun 2013

Therapy News and Research

TSRI scientists find emotion-related brain region plays major role in sustaining cocaine addiction

Using Swiss ball improves walking performance and muscle strength in AS patients

Society of Interventional Radiology releases Updates in Interventional Radiology 2013

PTSD patients with Met-66 allele of BDNF show poorer response to exposure therapy

WHO issues interim policy guidance on inclusion of bedaquiline to treat adults with MDR-TB

Constella® (linaclotide), for the symptomatic treatment of Irritable Bowel Syndrome with Constipation (IBS-C), is now available in Germany, UK and Nordic countries

Investigational all-oral interferon-free combination from Boehringer Ingelheim achieves 95% viral cure rates in genotype-1b hepatitis C patients

One-third of RA patients discontinue therapy within the first year of treatment

Study: Depression indicators are stronger predictors of work disability in early arthritis

State highlights: Ala. abortion law challenged in court; NYC officials try again on soda restrictions

New collaboration to advance cancer immunotherapy research

Black women with breast cancer experience treatment delays, new study finds

Radionuclide drug treatment planning goes to next level with 3-D patient models

Calif. budget agreement seeks balance, but leaves off some health care items

Effective method to restore sight to patients with blinding diseases

Diabetes Calculator for Kids: An electronic tool that helps parents manage their child's diabetes

3D motion-tracked PET imaging uses MR micro-coils to reduce movement-related imaging artifacts

New study shows treatment with brodalumab demonstrates clinical response in subjects with PsA

Combination of cytoreductive surgery and HIPEC may reduce mortality in abdominal cancers patients

Loyola University surgeon uses electrical stimulation as part of surgical technique to treat Bell's palsy

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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