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Discovery of impaired molecular pathway may help treat children with leukemia

Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013.

7 Jun 2013

Viewpoints: 'Reasonable' debate about health law's 'rate shock; 'absurdity' of Sebelius' account of fund raising; Obama killed the grand bargain

Many of us have been wondering whether it's possible to have an honest, reasonable debate about Obamacare. To my pleasant surprise, one may finally be starting.

7 Jun 2013

New gene variant found in human and animal tissue offers a promising treatment for cancer

A novel gene variant found in human and animal tissue may be a promising treatment for cancer, including breast and brain cancer, according to scientists from the Icahn School of Medicine at Mount Sinai.

7 Jun 2013

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

The drug ingenol mebutate (trade name: Picato) has been approved in Germany since November 2012 as a gel for the treatment of certain forms of actinic keratosis in adults. In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG) the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over diclofenac/hyaluronic acid gel. Such an added benefit cannot be derived from the dossier, however, as the drug manufacturer did not submit any relevant data: it did not cite any studies that directly compared ingenol mebutate with diclofenac/hyaluronic acid gel, and the method chosen by the manufacturer for an indirect comparison was unsuitable.

7 Jun 2013

Cancer Institute of New Jersey offers COMET-2 clinical trial to examine cabozantinib drug

The Cancer Institute of New Jersey is one of 50 sites across the nation to offer a clinical trial known as COMET-2 that examines whether the drug cabozantinib is effective in reducing bone pain in patients with prostate cancer that is no longer responsive to hormone therapy and has spread (metastasized) to other parts of the body.

7 Jun 2013

Aflibercept drug used for AMD shows no added benefit over current standard therapy

The drug aflibercept (trade name: Eylea) has been approved in Germany since November 2012 for the treatment of wet age-related macular degeneration (AMD). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG) the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over the current standard therapy.

7 Jun 2013

$Epidural steroid injection is associated with increased spinal fracture$

Epidural steroid injection is associated with increased spinal fracture

Most aging adults will experience back pain or a spinal disorder at some time in their life. In fact, about 25.8 million visits were made to physicians' offices due to primary back problems. Treatment focuses on pain relief and is available in both non-surgical (medication or physical therapy) and surgical forms.

7 Jun 2013

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives CE IVD Mark

BioFire Diagnostics, Inc. announced today that it obtained the CE IVD Mark under the European Directive on In Vitro Diagnostic Medical Devices for its FilmArray Blood Culture Identification Panel.

6 Jun 2013

Physiotherapist interaction with patient plays a significant role in pain reduction

How many times have you been to a physiotherapist where you've had more time in the waiting room than face-time with the physio? Well, according to University of Alberta physical therapy PhD grad Jorge Fuentes, how a physiotherapist interacts with a patient verbally, through eye contact, body language and listening skills is almost as important as the treatment itself.

6 Jun 2013

Study shows success in pinpointing individualized treatment for women with metastatic breast cancer

Funded by volleyball tournaments, a new study released this week shows success in pinpointing individualized treatment for women with metastatic breast cancer, according to George Mason University researchers.

6 Jun 2013

Instillation of chemotherapy can minimize recurrence and progression of bladder cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center led by Dr. Karim Chamie have found that more intense surveillance and treatment of bladder cancer in the first two years after diagnosis could reduce the number of patients whose cancer returns after treatment and lower the disease's death rate. The study was published online ahead of press today in the journal Cancer.

6 Jun 2013

Findings have implications for potential gene therapies for autism spectrum disorders

A gene linked to autism spectrum disorders that was manipulated in two lines of transgenic mice produced mature adults with irreversible deficits affecting either learning or social interaction.

6 Jun 2013

CTCA offers hope to Hispanics with advanced stage cancer

For the nation's fastest growing population, cancer ranked as the number one leading cause of death among Hispanics, based on a 2012 American Cancer Society report.

6 Jun 2013

Sustained engagement, partnership needed to implement new treatments for neglected diseases

Days after two landmark resolutions were adopted at the World Health Assembly - on neglected tropical diseases and on research and development, financing and coordination for the health needs of developing countries - over 400 scientists, representatives and ministers of health, ambassadors, national control programme representatives, African regulators, health workers, public health experts, and activists from 21 African countries and 10 others from around the world gather in Nairobi to take stock of health innovation for neglected diseases in Africa over the past decade.

6 Jun 2013

Consistent bedtime routine helps people with OSA adhere to prescribed treatment

A consistent bedtime routine is likely key to helping people with obstructive sleep apnea adhere to their prescribed treatment, according to Penn State researchers.

6 Jun 2013

Scientists develop first dual-action drug against melanoma skin cancer cells

Scientists are reporting development and successful lab tests on the first potential drug to pack a lethal one-two punch against melanoma skin cancer cells. Hit number one destroys cells in the main tumor, and the second hit blocks the spread of the cancer to other sites in the body, according to their report in the journal ACS Chemical Biology.

6 Jun 2013

Vanda reports clinical data of tasimelteon Phase III studies for treatment of Non-24-Hour Disorder

Vanda Pharmaceuticals Inc. presented additional entrainment and patient-level clinical data at SLEEP 2013, the 27th Annual Meeting of Associated Professional Sleep Societies in Baltimore, from its SET (Safety and Efficacy of Tasimelteon) and RESET (Randomized-withdrawal study of the Efficacy and Safety of Tasimelteon to treat Non-24-Hour Disorder) Phase III studies of tasimelteon, a circadian regulator for the treatment of Non-24-Hour Disorder (Non-24) in totally blind individuals.

6 Jun 2013

Accuray announces treatment of first patient with new TomoHDA System

Accuray Incorporated, announced today the first patient has been treated with its new TomoHDA System at Centre Oscar Lambret in Lille, France.

5 Jun 2013

Does krill oil help your arthritis?

Arthritis is a condition that affects 1 in 5 Australians. That means that 1.4m people in NSW alone, have a form of arthritis and try to manage the impact it has on their lives. There are a number of very common and effective ways to tackle the condition such as physical activity and exercise, physical therapy, healthy eating and traditional medicines. All of these methods can play a role in reducing the pain arthritis causes in people’s daily lives.

5 Jun 2013

Researchers to receive ASTRO Gold Medal for outstanding contributions to the field of radiation oncology

The American Society for Radiation Oncology (ASTRO) will award Amato J. Giaccia, PhD, Radhe Mohan, PhD, FASTRO, and Prabhakar Tripuraneni, MD, FASTRO, with the Society's highest honor—the ASTRO Gold Medal. The 2013 awardees will receive the ASTRO Gold Medal during the Awards Ceremony on Tuesday, September 24, at ASTRO's 55th Annual Meeting, September 22-25, 2013, at the Georgia World Congress Center in Atlanta.

5 Jun 2013

Therapy News and Research

Discovery of impaired molecular pathway may help treat children with leukemia

Viewpoints: 'Reasonable' debate about health law's 'rate shock; 'absurdity' of Sebelius' account of fund raising; Obama killed the grand bargain

New gene variant found in human and animal tissue offers a promising treatment for cancer

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

Cancer Institute of New Jersey offers COMET-2 clinical trial to examine cabozantinib drug

Aflibercept drug used for AMD shows no added benefit over current standard therapy

Epidural steroid injection is associated with increased spinal fracture

BioFire Diagnostics' FilmArray Blood Culture Identification Panel receives CE IVD Mark

Physiotherapist interaction with patient plays a significant role in pain reduction

Study shows success in pinpointing individualized treatment for women with metastatic breast cancer

Instillation of chemotherapy can minimize recurrence and progression of bladder cancer

Findings have implications for potential gene therapies for autism spectrum disorders

CTCA offers hope to Hispanics with advanced stage cancer

Sustained engagement, partnership needed to implement new treatments for neglected diseases

Consistent bedtime routine helps people with OSA adhere to prescribed treatment

Scientists develop first dual-action drug against melanoma skin cancer cells

Vanda reports clinical data of tasimelteon Phase III studies for treatment of Non-24-Hour Disorder

Accuray announces treatment of first patient with new TomoHDA System

Does krill oil help your arthritis?

Researchers to receive ASTRO Gold Medal for outstanding contributions to the field of radiation oncology

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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