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Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Sucampo Pharmaceuticals, Inc. and Takeda Pharmaceuticals U.S.A., Inc. announced today that the United States Food and Drug Administration has approved Sucampo's supplemental new drug application for AMITIZA (lubiprostone) (24 mcg twice daily) as the first and only oral medication for the treatment of opioid-induced constipation in adult patients with chronic, non-cancer pain.

24 Apr 2013

Janssen announces safety results from two Phase 3 studies of simeprevir in hepatitis C patients

Janssen R&D Ireland today announced primary efficacy and safety results from two global Phase 3 studies demonstrating that use of the investigational protease inhibitor simeprevir (TMC435) led to sustained virologic response 12 weeks after the end of treatment (SVR12) in 80 and 81 percent, respectively, of treatment-naive genotype 1 chronic hepatitis C adult patients with compensated liver disease, including all stages of liver fibrosis, when administered once daily with pegylated interferon and ribavirin.

24 Apr 2013

AACN awards Impact Research Grant to Detroit palliative care expert

The American Association of Critical-Care Nurses recently awarded an AACN Impact Research Grant to Margaret "Meg" Campbell, RN, PhD, FAAN, a nationally known expert in hospital-based palliative care and end-of-life issues.

24 Apr 2013

Some Boston Marathon bomb victims will face insurance coverage limits

ayments for prosthetics, rehabilitation and a range of other treatments may fall outside some insurance limits and could continue long into the future.

24 Apr 2013

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Researchers have long known that cancerous tumors grow collections of abnormal blood cells, the fuel that feeds this disease and keeps it growing. Now, new evidence in an animal model suggests that blood vessels in the fat tissue of obese individuals could provide the same purpose-and could provide the key to a new way for people to lose weight.

24 Apr 2013

Frequent binge drinking in college increases risk of cardiovascular disease later in life

Frequent binge drinking in college can cause more than a hangover. Regularly consuming multiple drinks in a short window of time can cause immediate changes in circulation that increase an otherwise healthy young adult's risk of developing cardiovascular disease later in life, according to research published online today in the Journal of the American College of Cardiology.

24 Apr 2013

McGraw-Hill publishes preeminent textbook for pulmonary physiology in Lange Physiology Series

The 8th Edition of PULMONARY PHYSIOLOGY by Dr. Michael G. Levitzky, Professor of Physiology, Anesthesiology, and Cardiopulmonary Science at LSU Health Sciences Center New Orleans, was published this month by McGraw-Hill in its Lange Physiology Series.

24 Apr 2013

Rheumatoid arthritis diagnosis: an interview with Dr. Stan Naides, Medical Director, Quest Diagnostics

Rheumatoid arthritis (RA) is an autoimmune disorder that can cause debilitating joint damage. In cases of RA, the immune system attacks the body’s own tissues, especially the membranes that line the joints. As a result, fluid builds up in the joints, causing pain and systemic inflammation, leading to joint destruction if untreated.

From Quest Diagnostics 23 Apr 2013

Study: Stressful situations at work can have negative impact on cardiovascular system and metabolism

Stressful situations at work can have a negative impact on the cardiovascular system and the metabolism. Stress, which is transmitted by direct and indirect signaling pathways, leads to an inflammatory response in the body, which can trigger cardiovascular diseases, amongst others.

23 Apr 2013

Study shows intraventricular chemotherapy increases overall survival in LMC patients

Lung cancer is one of the most common primary cancers that cause leptomeningeal carcinomatosis (LMC), when cancer spreads to the membranes surrounding the spinal cord and brain. Cases of LMC have increased because of the improved survival of lung cancer patients with the help of new advances in treatment.

23 Apr 2013

Study suggests lung cancer patients with HER2 mutations may benefit from anti-HER2 drugs

New results from a retrospective study conducted in Europe suggest that anti-HER2 treatments, like the widely used breast cancer agent trastuzumab (Herceptin), have anti-cancer effects in a small subset of patients with advanced non-small cell lung cancer (NSCLC) harboring specific HER2 protein mutations.

23 Apr 2013

Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are the main cause of cancer-related deaths.

23 Apr 2013

Animal models of Huntington's disease allow better insights into disease's genetics

Scientific progress in Huntington's disease (HD) relies upon the availability of appropriate animal models that enable insights into the disease's genetics and/or pathophysiology.

23 Apr 2013

BTS launches belt to prevent lower back pain problems

FIK, Tecnalia and BTS launch a belt to prevent lower back pain problems and provide rehabilitation at home and at work. The Lumbia device can be used for patient´s assessment, and for therapy during postural re-education.

23 Apr 2013

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression of two enzymes (JMJD2b and SUV39H1) that control the folding of DNA.

23 Apr 2013

Study suggests specific form of vitamin E supplement improves function of blood vessels

Taking a specific form of a vitamin E supplement can accelerate the health benefits that occur when people quit smoking, new research suggests.

23 Apr 2013

Researchers explore new technique to determine the activity of different calcium channels in cancer cells

Two Wayne State University researchers are working on a technique that could lead to easier, faster identification of cancer tumors that can be effectively treated by calcium channel-based therapies.

23 Apr 2013

Clinical data on simeprevir for treatment of hepatitis C patients to be presented at EASL meeting

Medivir AB today announces that data will be presented on the investigational protease inhibitor simeprevir (TMC435) for the treatment of genotype 1 hepatitis C patients.

23 Apr 2013

First Edition: April 23, 2013

Today's headlines include reports about immigrant patients' health care as well as the coverage limits that some victims of the Boston Marathon bombings might face.

23 Apr 2013

Gilead Sciences to present results from four Phase 3 clinical trials at International Liver Congress 2013

Gilead Sciences, Inc. today announced that detailed results from four Phase 3 clinical trials (NEUTRINO, FISSION, POSITRON and FUSION) evaluating sofosbuvir, the company's investigational once-daily nucleotide NS5B inhibitor for the treatment of chronic hepatitis C virus infection, will be presented this week in oral sessions at the 48th Annual Meeting of the European Association for the Study of the Liver in Amsterdam, The Netherlands.

23 Apr 2013

Therapy News and Research

Sucampo's supplemental new drug application for AMITIZA gets FDA approval

Janssen announces safety results from two Phase 3 studies of simeprevir in hepatitis C patients

AACN awards Impact Research Grant to Detroit palliative care expert

Some Boston Marathon bomb victims will face insurance coverage limits

Therapy originally conceived for cancer could hold promise for weight loss, say researchers

Frequent binge drinking in college increases risk of cardiovascular disease later in life

McGraw-Hill publishes preeminent textbook for pulmonary physiology in Lange Physiology Series

Rheumatoid arthritis diagnosis: an interview with Dr. Stan Naides, Medical Director, Quest Diagnostics

Study: Stressful situations at work can have negative impact on cardiovascular system and metabolism

Study shows intraventricular chemotherapy increases overall survival in LMC patients

Study suggests lung cancer patients with HER2 mutations may benefit from anti-HER2 drugs

Individual cancer cells in blood stream are responsible for metastases in breast cancer patients

Animal models of Huntington's disease allow better insights into disease's genetics

BTS launches belt to prevent lower back pain problems

Researchers find deficiency in anti-tumor protein can delay DNA repair after radiation treatment

Study suggests specific form of vitamin E supplement improves function of blood vessels

Researchers explore new technique to determine the activity of different calcium channels in cancer cells

Clinical data on simeprevir for treatment of hepatitis C patients to be presented at EASL meeting

First Edition: April 23, 2013

Gilead Sciences to present results from four Phase 3 clinical trials at International Liver Congress 2013

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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