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Study suggests bright light therapy may improve sleep and brain function post mild TBI

A new study suggests that bright light therapy may improve sleep, cognition, emotion and brain function following mild traumatic brain injury (TBI).

1 Jun 2013

RPCI, Jasco Pharmaceuticals partner to advance development of cancer therapy

A new partnership, first of its kind for both organizations, will see Roswell Park Cancer Institute and Jasco Pharmaceuticals, LLC collaborating to advance development of an investigational pharmacological therapy that shows promise for treating both solid-tumor cancers and hematologic malignancies.

1 Jun 2013

Researchers discover potential biomarkers to identify patients with head and neck cancer

Researchers from Fox Chase Cancer Center will present data at the 49th Annual Meeting of the American Society of Clinical Oncology on Saturday, June 1, which shows the discovery of potential biomarkers that may be used to identify patients with head and neck cancer whose tumors are unlikely to respond to treatment by the targeted therapy cetuximab-a type of monoclonal antibody.

1 Jun 2013

New clinical practice guidelines on sleep apnea, driving risk on non-commercial drivers

The American Thoracic Society has released new clinical practice guidelines on sleep apnea, sleepiness, and driving risk on non-commercial drivers.

1 Jun 2013

Findings could potentially lead to new drug therapy for Cushing disease

Cushing disease is a life-threatening disorder most commonly triggered by tumors, often benign, in the pituitary glands, resulting in excess production of adrenocorticotrophic hormone.

1 Jun 2013

Health care questions: Do medical homes improve outcomes? Is high tech worth the cost?

Joseph Ashwal, MD, knew a good deal when he saw one. … The program -- the Total Care and Cost Improvement Program -- has been a game-changer for Ashwal and his practice, Frederick Primary Care Associates, yielding more than a 20 percent increase in payments from CareFirst last summer for the group's success during 2011 in lowering spending by keeping patients out of the hospital and emergency departments.

1 Jun 2013

Nanoparticle-based immunotherapy for cancer

The German Research Foundation has established a new Collaborative Research Center on "Nanodimensional polymer therapeutics for tumor therapy" (CRC 1066) at Johannes Gutenberg University Mainz and the Max Planck Institute for Polymer Research (MPI-P).

1 Jun 2013

Study supports future possibility of personalized medicine for cervical cancer

Doctors at Washington University School of Medicine in St. Louis have shown that testing cervical tumors before treatment for vulnerability to chemotherapy predicts whether patients will do well or poorly with standard treatment.

1 Jun 2013

Theoretical mathematical models offer insights into therapeutic, prevention strategies for HIV

The first few hours to days following exposure to human immunodeficiency virus can be of critical importance in determining if infection occurs in a patient. But the low numbers of viruses and infected cells at this stage makes it very difficult to study these events in humans or animal models.

1 Jun 2013

Five studies on breast, colon and colorectal cancer to be presented at ASCO Annual Meeting

Agendia, a world leader in molecular cancer diagnostics, today announced that results from five studies focused on breast, colon and colorectal cancer will be presented at the upcoming American Society of Clinical Oncology Annual Meeting to be held May 31-June 4, 2013 at McCormick Place in Chicago.

1 Jun 2013

MannKind completes AFREZZA Phase 3 clinical study in patients with type 1 diabetes

MannKind Corporation today announced that all follow-up visits have been completed for the patients enrolled in Study 171, a Phase 3 clinical study of AFREZZA (insulin human [rDNA origin]) inhalation powder, an investigational, ultra rapid-acting mealtime insulin therapy, administered using MannKind's next-generation inhaler. MannKind expects to release data from this study later this summer.

1 Jun 2013

New nanoparticle gene delivery method to prevent stenting procedure complications

Stent angioplasty saves lives, but there often are side effects and complications related to the procedure, such as arterial restenosis and thrombosis. In the June 2013 issue of The FASEB Journal, however, scientists report that they have discovered a new nanoparticle gene delivery method that may overcome current limitations of gene therapy vectors and prevent complications associated with the stenting procedure.

1 Jun 2013

Only one-fifth of RA patients had overall adherence rate to prescribed oral medications, study finds

A new study conducted in an ethnically diverse and predominantly low income population found that only one-fifth of rheumatoid arthritis patients had an overall adherence rate to prescribed oral medications at 80% or greater.

1 Jun 2013

Alios begins oral dosing of ALS-8176 in Phase 1 clinical trial for RSV infection

Alios BioPharma, Inc. today announced that it has begun oral dosing of ALS-8176 in a Phase 1 clinical trial. ALS-8176 is a structurally novel, anti-respiratory syncytial virus (RSV) nucleoside analog that is being developed for the treatment of acute RSV infection.

31 May 2013

Study: Young women with breast cancer often choose mastectomy over surgical procedure

A new study of young women with breast cancer has found that most chose to have a mastectomy rather than a surgical procedure that would conserve the breast, researchers will report at the 49th Annual Meeting of the American Society of Clinical Oncology, May 31-June 4, in Chicago.

31 May 2013

New avatar system could provide quick and effective therapy for schizophrenia

An avatar system that enables people with schizophrenia to control the voice of their hallucinations is being developed by researchers at UCL with support from the Wellcome Trust.

31 May 2013

Vanda Pharmaceuticals announces submission of tasimelteon NDA to FDA

Vanda Pharmaceuticals Inc. today announced the submission of a New Drug Application to the U.S. Food and Drug Administration for tasimelteon, a circadian regulator.

31 May 2013

First Edition: May 31, 2013

Today's early morning highlights from the major news organizations, including reports from the administration about the number of insurers that will be offering policies on the new online marketplaces.

31 May 2013

Exelixis starts phase 3 pivotal trial of cabozantinib for treatment of metastatic renal cell carcinoma

Exelixis, Inc. today announced it has initiated METEOR, a phase 3 pivotal trial comparing cabozantinib to everolimus in patients with metastatic renal cell carcinoma who have experienced disease progression following treatment with at least one prior VEGFR tyrosine kinase inhibitor.

31 May 2013

NYC public health officials launch new program to locate lost to follow-up patients with HIV

Public health officials in New York City have launched a successful program to locate HIV-positive patients who have been "lost to follow-up" and reconnect them with treatment services, reports a study published in AIDS, official journal of the International AIDS Society.

31 May 2013

Therapy News and Research

Study suggests bright light therapy may improve sleep and brain function post mild TBI

RPCI, Jasco Pharmaceuticals partner to advance development of cancer therapy

Researchers discover potential biomarkers to identify patients with head and neck cancer

New clinical practice guidelines on sleep apnea, driving risk on non-commercial drivers

Findings could potentially lead to new drug therapy for Cushing disease

Health care questions: Do medical homes improve outcomes? Is high tech worth the cost?

Nanoparticle-based immunotherapy for cancer

Study supports future possibility of personalized medicine for cervical cancer

Theoretical mathematical models offer insights into therapeutic, prevention strategies for HIV

Five studies on breast, colon and colorectal cancer to be presented at ASCO Annual Meeting

MannKind completes AFREZZA Phase 3 clinical study in patients with type 1 diabetes

New nanoparticle gene delivery method to prevent stenting procedure complications

Only one-fifth of RA patients had overall adherence rate to prescribed oral medications, study finds

Alios begins oral dosing of ALS-8176 in Phase 1 clinical trial for RSV infection

Study: Young women with breast cancer often choose mastectomy over surgical procedure

New avatar system could provide quick and effective therapy for schizophrenia

Vanda Pharmaceuticals announces submission of tasimelteon NDA to FDA

First Edition: May 31, 2013

Exelixis starts phase 3 pivotal trial of cabozantinib for treatment of metastatic renal cell carcinoma

NYC public health officials launch new program to locate lost to follow-up patients with HIV

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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