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Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Placental changes may increase the risk of asthma and allergies in children

Changes in the placenta may increase the risk of children developing asthma and allergies, as shown in new research from örebro University.

8 Oct 2024

Replicating Lewy body formation in living neurons to understand Parkinson's disease

Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.

8 Oct 2024

Brainstem inflammation may explain long Covid symptoms

Damage to the brainstem – the brain's 'control center' – is behind long-lasting physical and psychiatric effects of severe Covid-19 infection, a study suggests.

8 Oct 2024

Common breast cancer therapies may speed up aging, study shows

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center has revealed that common breast cancer treatments, including chemotherapy, radiation, and surgery, may accelerate the biological aging process in breast cancer survivors.

8 Oct 2024

GLP-1 drugs protect brain health by improving neurovascular function and reducing inflammation

Research highlights how GLP-1 receptor agonists may improve brain health by targeting the neurovascular unit, linking metabolic health to cognitive function. It suggests potential therapies for neurodegenerative diseases like Alzheimer's.

7 Oct 2024

Researchers identify key mechanism behind atherosclerosis in Hutchinson-Gilford progeria syndrome

A team of researchers from the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), the Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC), and the Instituto de Ciencias de Materiales de Madrid (ICMM-CSIC) has made a significant breakthrough in understanding the underlying causes of cardiovascular disease in patients with Hutchinson-Gilford progeria syndrome (HGPS), an ultra-rare genetic disorder that accelerates the aging process.

7 Oct 2024

Identical twins study uncovers insights into multiple sclerosis mechanisms

Multiple sclerosis (MS) is a chronic inflammatory disease in which the immune system attacks the central nervous system.

4 Oct 2024

LXRβ emerges as a promising target for depression and anxiety treatments

In a state-of-the-art Bench to Bedside review published in the journal Brain Medicine (Genomic Press), researchers Dr. Xiaoyu Song and Professor Jan-Åke Gustafsson from the University of Houston and Karolinska Institutet (Sweden) shed light on the therapeutic potential of liver X receptor beta (LXRβ) in treating depression and anxiety.

4 Oct 2024

Early-life trauma increases pain, depression in final years, study finds

Repeating a school year, experiencing parental abuse or engaging in armed combat have far-reaching long-term effects. Lifetime trauma may even worsen end-of-life pain and discomfort, depression and loneliness.

4 Oct 2024

Lithium aspartate fails to improve long COVID symptoms, but higher doses may hold promise

Lithium aspartate at 10-15 mg/d is ineffective for treating cognitive dysfunction and fatigue in long COVID, but higher doses may offer potential benefits based on a small follow-up study.

3 Oct 2024

New study explores UBA1 dysfunction in VEXAS and cancer

A new research perspective was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "UBA1 dysfunction in VEXAS and cancer."

3 Oct 2024

Researchers discover potential risk marker for cardiovascular disease in women

Researchers at Karolinska Institutet have identified a new potential risk marker for cardiovascular disease in women.

3 Oct 2024

Florida breast cancer foundation funds two UCF projects to combat breast cancer

As Breast Cancer Awareness Month begins, two College of Medicine cancer researchers have received statewide grants to support their innovative projects to fight a disease that strikes one in eight American women.

3 Oct 2024

Low-dose lithium fails in long COVID trial, but higher doses show potential

A small University at Buffalo clinical trial has found that at low doses, lithium aspartate is ineffective in treating the fatigue and brain fog that is often a persistent feature of long COVID; however, a supplemental dose-finding study found some evidence that higher doses may be effective.

3 Oct 2024

Mediterranean diet significantly lowers heart failure risk, especially in women

Increased adherence to the Mediterranean diet significantly lowers the risk of heart failure, especially in women, according to a recent European meta-analysis. The diet's anti-inflammatory and antioxidant properties are key to its protective effects.

3 Oct 2024

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis, which is the process of breaking blood clots, and heightened inflammatory responses.

3 Oct 2024