Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

Cell trafficking finding may aid drug development

With findings highlighted on a recent cover of Developmental Cell , researchers at Weill Cornell Medical College in New York City have shed important new light on key trafficking mechanisms within epithelial cells. Epithelial cells line the outside of nearly all organs.

12 Dec 2007

Protein-dependent "switch" regulates intracellular trafficking in epithelial cells

12 Dec 2007

Lipids in the brain an important factor for Alzheimer's disease

As the most common form of dementia in the Western world, Alzheimer's disease carries enormous implications for our ageing society.

10 Dec 2007

Diet low in carbohydrates reduces inflammation and blood saturated fat in metabolic syndrome

Metabolic syndrome is a condition afflicting one quarter to one third of adult men and women and is an established pre-cursor to diabetes, coronary heart disease, and other serious illnesses.

4 Dec 2007

Communication key to tackling cardiovascular disease

Despite the increasing evidence that managing high cholesterol reduces cardiovascular events, many people do not achieve recommended lipid levels.

27 Nov 2007

Newly completed genome sequence may provide new treatment options for dandruff

Scientists from P&G Beauty announced that they successfully sequenced the complete genome for Malassezia globosa (M. globosa) , a naturally occurring fungus responsible for the onset of dandruff and other skin conditions in humans.

6 Nov 2007

New investigational combination pill improves multiple cholesterol disorders

Patients treated with a new investigational combination pill showed significant improvements in cholesterol, triglycerides and other key lipids that lead to heart disease, according to results presented at the American Heart Association's Scientific Sessions.

5 Nov 2007

Scientists discover new causes for neurodegeneration

Diseases that cause neurons to break-down, such as Alzheimer's, Multiple Sclerosis and Creutzfeldt-Jakob disease (Mad Cow Disease), continue to be elusive to scientists and resistant to treatments.

25 Oct 2007

Increased intestinal permeability by exogenous sphingomyelinase

Many signaling molecules involved in the pathogenesis of IBD, such as TNF or IFN, infections with bacteria or viruses and ionizing radiation, may cause an alteration of the lipid composition in the cell membrane by activation of sphingomyelinases (SMases).

24 Oct 2007

Study explains why physical activity is beneficial in preventing heart attack and stroke

It is well known that physical activity can improve cardiovascular health. But it's the impact exercise has on specific known risk factors that accounts for about 60 percent of that improvement, researchers reported in Circulation: Journal of the American Heart Association.

22 Oct 2007

First animal model of age-related macular degeneration

Researchers at the University of Pennsylvania School of Medicine have created the first animal model of age-related macular degeneration (AMD) caused by a mutation known to produce disease in people, an important first step in developing treatments.

10 Oct 2007

Linking two molecular pieces may offer new approaches to treating Alzheimer's disease

Researchers have uncovered a biological link between the protein whose mutation causes early-onset Alzheimer's disease (AD) and a gene variant linked to late-onset AD.

4 Oct 2007

Cholesterol levels both high and low linked to premature births

A new study suggests that not only is a very low level of cholesterol a danger to pregnant women, but high cholesterol too increases the risk of premature birth.

3 Oct 2007

Biologists link Huntington's disease to health benefits in young

For years researchers in neurology have believed that people with Huntington's disease have more children than the general population because of behavioral changes associated with the disease that lead to sexual promiscuity.

26 Sep 2007

Scientists decipher mechanism behind antimicrobial 'hole punchers'

In the battle against bacteria, researchers have scored a direct hit.

21 Sep 2007

Process of necrosis redefined in landmark study

A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered as part of a regulated response to stress by a powerful protein, SRP-6, that can potentially halt necrosis in its path.

21 Sep 2007

Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits

Researchers from Boston University School of Medicine (BUSM), Boston University School of Public Health (BUSPH), and the National Heart, Lung and Blood Institute (NHLBI), have completed analyses of a genome-wide scan on a group of two generations of participants from the landmark Framingham Heart Study (FHS).

20 Sep 2007

Pocket guidelines for assessment and management of cardiovascular risk

A new book of pocket-charts that will help health workers to identify people at risk of heart attacks and strokes and save lives by prescribing the most appropriate treatment is published today by the World Health Organization (WHO). The charts can be adapted for use in any setting, in any country, with any patient.

12 Sep 2007

Yellow plant pigments may lower risk for age-related eye disease

Consuming higher levels of the yellow plant pigments lutein and zeaxanthin may be associated with a lower risk for age-related macular degeneration, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Sep 2007

A chink in bacteria's armor

Biomedical researchers at Boston University's College of Engineering may have discovered the path toward developing better drugs capable of defeating so-called “superbugs,” bacteria that have developed resistance to common antibiotics. The researchers have discovered a previously unknown chain of events occurring in bacteria that opens to door to new avenues of research.

10 Sep 2007