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Multisystem intervention could potentially prevent or reverse frailty, research shows

Physicians understand frailty as a dysregulation among multiple systems in the body that make it less resilient and unable to recover completely when faced with a physical challenge such as injury or illness.

8 Mar 2021

Robotic systems gain patient approval for contactless care

In the age of COVID-19, mobile robotic telehealth systems could help clinicians and patients interact without contact. Last spring, some health care systems deployed robotic systems within a hospital to evaluate and interact with patients.

5 Mar 2021

Delayed detection of oral fluid anti-SARS-CoV-2 antibodies increases the time to viral clearance

A prospective observational study has revealed that the late appearance of anti-SARS-CoV-2 antibodies in oral fluid, absence of fever as an early symptom, and elevated BMI are associated with delayed clearance of viral RNA in mild to moderate COVID-19 patients.

4 Mar 2021

Reduced ambulatory function in cancer survivors associated with increased risk of death

Bottom Line: Cancer survivors had a greater risk of reduced ambulatory function, which was associated with an increased risk of death.

4 Mar 2021

Researchers discover a safe, effective, reversible male contraceptive agent

In a new paper published by Nature Communications, The Lundquist Institute (TLI) Investigator Wei Yan, MD, PhD, and his research colleagues spell out an innovative strategy that has led to the discovery of a natural compound as a safe, effective and reversible male contraceptive agent in pre-clinical animal models

4 Mar 2021

Study: Salivary gland ectasia reflects hyperinflammatory response to COVID-19

The clinical picture of COVID-19 in various target organs has been extensively studied and described, but relatively little is known about the characteristics of oral cavity involvement.

4 Mar 2021

Study examines the variability in opioid prescriptions for common orthopedic procedures

A new review article published in the March issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS) examines the variability that exists in opioid prescribing patterns across the United States for many common orthopedic procedures.

4 Mar 2021

New substance suppresses the growth of harmful bacteria that cause periodontitis

Targeted, efficient and with few side effects: A new method for combating periodontitis could render the use of broad-spectrum antibiotics superfluous.

3 Mar 2021

Proportion of children in Medicaid managed care plans increases from 65% to 94%

Nationally, the number of children under age 21 enrolled in Medicaid grew from 23.5 million in 2000 to 40.5 million in 2017, with the proportion of children in Medicaid managed care plans increasing from 65 percent to 94 percent, according to a study from Ann & Robert H. Lurie Children's Hospital of Chicago published in the journal Academic Pediatrics.

1 Mar 2021

School-based cavity prevention program reduces health disparities, brings dental care to children

A school-based cavity prevention program involving nearly 7,000 elementary school students reduced cavities by more than 50 percent, according to a study led by researchers at NYU College of Dentistry.

1 Mar 2021

NYU Oral Cancer Center receives $3.1 million grant to explore the interplay between nerves and cancer

NYU Oral Cancer Center has been awarded a five-year, $3.1 million grant (R01 CA231396) by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

1 Mar 2021

Free-ranging minks exhibit high titers of SARS-CoV-2 antibodies in Utah

Researchers at the U.S. Centers for Disease Control and Prevention (CDC) report outbreaks of coronavirus disease (COVID-19) on mink farms in Utah, United States. They surveyed around farms for evidence of exposure and found high SARS-CoV-2 titers, suggesting a possible viral transmission pathway to native wildlife.

28 Feb 2021

Researchers use new approaches to address premature failure of dental restorations

How can dental restorations - such as fillings and crowns - be made to last longer? A new research group centered at Charité - Universitätsmedizin Berlin and Technische Universität (TU) Berlin plans to address this topic by utilizing approaches from both materials science and dentistry.

27 Feb 2021

KHN’s ‘What the health?’: Staffing up at HHS

More than a month into President Joe Biden’s term, nominees to fill some of the top posts at the Department of Health and Human Services are finally getting confirmation hearings in the Senate, starting with the nominee for secretary, California Attorney General Xavier Becerra.

26 Feb 2021

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

A new study by researchers in the U.S. further supports the hypothesis that the unregulated release of inflammatory cytokines is responsible for the local and systemic inflammation that is associated with multi-organ damage and death in severe COVID-19.

26 Feb 2021

Post-surgery opioid prescribing guideline leads to high patient satisfaction with pain management

A prescribing guideline tailored to patients' specific needs reduced the number of opioid pills prescribed after major surgery with researchers reporting a greater than 90 percent patient satisfaction rate with pain management and the highest compliance rate to date with appropriate disposal of leftover pills.

25 Feb 2021

SNX-5422 could make an effective COVID-19 prophylactic, says study

SNX-5422 is a heat shock protein 90 (Hsp90) inhibitor currently undergoing clinical trials as a cancer therapeutic. A recent study examines the applicability of repurposing the drug towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication inhibition.

25 Feb 2021

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Insilico Medicine has demonstrated a breakthrough in Artificial Intelligence ("AI") and drug discovery -- linking together generative chemistry and biology for the first time -- to discover a novel preclinical candidate addressing idiopathic pulmonary fibrosis ("IPF") and be validated with multiple human cell and animal model experiments.

25 Feb 2021

Study takes a closer look at the impact of COVID-19 pandemic on dental hygienists

Despite having been designated as high risk for COVID-19 by the Occupational Safety and Health Administration, a new study finds 3.1 percent of dental hygienists have had COVID-19 based on data collected in October 2020.

24 Feb 2021

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

A team of researchers examined PT150, which is an allosteric modulator of androgen and glucocorticoid receptors, to assess whether it had any antiviral activity or immunomodulatory activity to decrease the hyperinflammatory response of SARS-CoV-2 infection.

24 Feb 2021

Oral News and Research

Multisystem intervention could potentially prevent or reverse frailty, research shows

Robotic systems gain patient approval for contactless care

Delayed detection of oral fluid anti-SARS-CoV-2 antibodies increases the time to viral clearance

Reduced ambulatory function in cancer survivors associated with increased risk of death

Researchers discover a safe, effective, reversible male contraceptive agent

Study: Salivary gland ectasia reflects hyperinflammatory response to COVID-19

Study examines the variability in opioid prescriptions for common orthopedic procedures

New substance suppresses the growth of harmful bacteria that cause periodontitis

Proportion of children in Medicaid managed care plans increases from 65% to 94%

School-based cavity prevention program reduces health disparities, brings dental care to children

NYU Oral Cancer Center receives $3.1 million grant to explore the interplay between nerves and cancer

Free-ranging minks exhibit high titers of SARS-CoV-2 antibodies in Utah

Researchers use new approaches to address premature failure of dental restorations

KHN’s ‘What the health?’: Staffing up at HHS

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

Post-surgery opioid prescribing guideline leads to high patient satisfaction with pain management

SNX-5422 could make an effective COVID-19 prophylactic, says study

Insilico Medicine discovers novel preclinical candidate to address idiopathic pulmonary fibrosis

Study takes a closer look at the impact of COVID-19 pandemic on dental hygienists

Corticosteroid receptor inhibitor shows anti-SARS-CoV-2 activity in vivo

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