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New biomedical tool using nanoparticles could improve therapies for many diseases

A new biomedical tool using nanoparticles that deliver transient gene changes to targeted cells could make therapies for a variety of diseases - including cancer, diabetes and HIV - faster and cheaper to develop, and more customizable.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

Scientists aim is to better understand effects of DNA damage on aging process

The heredity substance DNA is the blueprint of our life. Like an instruction manual it contains all the information needed for cells and the body to function properly.

30 Aug 2017

New review explores potential of fetal membranes for regenerative medicine

A new review looks at the potential of fetal membranes, which make up the amniotic sac surrounding the fetus during pregnancy, for regenerative medicine.

30 Aug 2017

Defect in DNA repair machinery causes underdevelopment of neural network

DNA is the computer code that programs every event in the body. Despite the importance of DNA fidelity, as the body develops, cells grow and replicate, DNA is constantly turned over. This repeated process can compromise the DNA, which is why the body has many DNA repair machineries.

30 Aug 2017

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

An international study of integrated HHV-6 has discovered that a small number of human ancestors, one from about 24,000 years ago, have been responsible for transmitting ancient strains of the virus to individuals today - affecting about a million people in the UK alone.

30 Aug 2017

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists have discovered a network of genes and genetic regulatory elements in the lining of the intestines that has stayed remarkably the same from fishes to humans. Many of these genes are linked to human illnesses, such as inflammatory bowel diseases, diabetes and obesity.

30 Aug 2017

Stabilizing TREM2 could be viable therapeutic strategy to combat Alzheimer's disease

A gene called triggering receptor expressed on myeloid cells 2, or TREM2, has been associated with numerous neurodegenerative diseases, such as Alzheimer's disease, Frontotemporal lobar degeneration, Parkinson's disease, and Nasu-Hakola disease. Recently, a rare mutation in the gene has been shown to increase the risk for developing Alzheimer's disease.

30 Aug 2017

Researchers demystify interdomain communication pathway in Hsp70 protein

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has demystified the pathway of interdomain communication in a family of proteins known as Hsp70s - a top target of dozens of research laboratories trying to develop new anti-cancer drugs, antibiotics and treatments for Alzheimer's and Parkinson's diseases.

30 Aug 2017

Heat therapy could be promising treatment to help fight against cancer, autoimmune problems

Heat therapy may be a promising treatment in the fight against cancer, autoimmune problems and efforts to avoid organ rejection in transplant patients, according to researchers at the University of Kentucky.

30 Aug 2017

UCLA professor offers 10 tips for college students to ensure good gynecologic health

For young women heading off to college, it can be a time filled with the excitement of living away from home. This new sense of independence should also include taking charge of one's own health, says Dr. Aparna Sridhar, an assistant professor of obstetrics and gynecology at the David Geffen School of Medicine at UCLA.

30 Aug 2017

Study sheds new light on gene fusion in bladder and brain cancer

A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.

30 Aug 2017

Scientists identify novel role for retrotransposons in shaping embryonic chromatin landscape

Retrotransposons are repetitive elements that form almost half of the mammalian genome. Even though they are so common, they have previously been considered to be fairly insignificant.

30 Aug 2017

Researchers develop new approach to efficiently produce versatile antibody therapies

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy.

29 Aug 2017

FDA grants accelerated approval to new treatment for children with Chagas disease

The U.S. Food and Drug Administration today granted accelerated approval to benznidazole for use in children ages 2 to 12 years old with Chagas disease. It is the first treatment approved in the United States for the treatment of Chagas disease.

29 Aug 2017

Tiny tears in membranes of bone cells may be key to strong bones

The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say.

29 Aug 2017

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukemia patients who have undergone stem cell transplantation.

29 Aug 2017

Placenta-on-a-chip device mimics microenvironment of malaria in the womb to develop treatments

Malaria, one of the most severe public health problems, affected 212 million people worldwide in 2015. This life-threatening disease is caused by parasites that are transmitted to humans through the bites of infected female Anopheles mosquitoes.

29 Aug 2017

New imaging technique can help assess quality of early-stage embryos

Researchers at the ARC Centre of Excellence for Nanoscale BioPhotonics, led by the University of Adelaide, have successfully developed an advanced new imaging technique, which can help assess the quality of early-stage embryos.

29 Aug 2017

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

New blood vessels branch out of preexisting ones is via a process called angiogenesis. Although this is essential for survival, development and wound healing, on the flip side, it also feeds and progresses malignant tumors, as well as other diseases.

29 Aug 2017

B Cell News and Research

New biomedical tool using nanoparticles could improve therapies for many diseases

FDA approves first cell-based gene therapy for use in the United States

Scientists aim is to better understand effects of DNA damage on aging process

New review explores potential of fetal membranes for regenerative medicine

Defect in DNA repair machinery causes underdevelopment of neural network

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Stabilizing TREM2 could be viable therapeutic strategy to combat Alzheimer's disease

Researchers demystify interdomain communication pathway in Hsp70 protein

Heat therapy could be promising treatment to help fight against cancer, autoimmune problems

UCLA professor offers 10 tips for college students to ensure good gynecologic health

Study sheds new light on gene fusion in bladder and brain cancer

Scientists identify novel role for retrotransposons in shaping embryonic chromatin landscape

Researchers develop new approach to efficiently produce versatile antibody therapies

FDA grants accelerated approval to new treatment for children with Chagas disease

Tiny tears in membranes of bone cells may be key to strong bones

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

Placenta-on-a-chip device mimics microenvironment of malaria in the womb to develop treatments

New imaging technique can help assess quality of early-stage embryos

IBS scientists uncover key regulator of normal as well as pathological angiogenesis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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