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Research reveals vitamin C does not reduce urate levels in gout patients

Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with established gout. Vitamin C supplementation, alone or in combination with allopurinol, appears to have a weak effect on lowering uric acid levels in gout patients according to the results published in the American College of Rheumatology (ACR) journal, Arthritis & Rheumatism.

17 May 2013

Research shows new neural circuits arise when hippocampus is disabled

When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the regions of the brain involved in creating those alternate pathways - often far from the damaged site.

17 May 2013

Cedars-Sinai launches new clinical trial to study effects of cabozantinib in prostate cancer patients

Researchers at Cedars-Sinai have launched a new clinical trial to investigate the effects of a cancer-fighting drug therapy that has shown favorable outcomes in patients with advanced metastatic prostate cancer.

17 May 2013

Preclinical study shows PLX cells may help reverse symptoms associated with preeclampsia

Could the answer to repairing the ailing placenta in preeclampsia lie within the stem cells of a healthy placenta? New promising evidence may lead scientists to answer that question.

17 May 2013

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

The hardening of arteries is a hallmark of atherosclerosis, an often deadly disease in which plaques, excessive connective tissue, and other changes build up inside vessel walls and squeeze off the flow of oxygen-rich blood throughout the body.

17 May 2013

Sonendo unveils Multisonic Ultracleaning System at AAE meeting

Sonendo, a developer of a revolutionary technology for the endodontic marketplace, unveiled its new Multisonic Ultracleaning System at the recent American Association of Endodontics in Hawaii, a national, member-based organization dedicated to endodontic education.

17 May 2013

Scientists reveal inside story of European regulatory review and approval of Glybera

The scientists who led the team that developed Glybera, the first gene therapy drug approved for use in the Western world, provide a fascinating first-person account of their pioneering work in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

16 May 2013

People suffering from PTSD have risk of developing type 2 diabetes

The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the University Hospital Gieβen and Marburg who worked with data from the population-based KORA cohort study.

16 May 2013

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

A new oral targeted drug, idelalisib (GS-1101), has the potential to stave off the need for additional treatments for relapsed or treatment-resistant chronic lymphocytic leukemia, according to a study led in part by Dana-Farber Cancer Institute investigators.

16 May 2013

Study underscores new paradigm in cancer therapy

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers.

16 May 2013

$Study: Long-term mortality in patients with refractory angina is surprisingly low$

Study: Long-term mortality in patients with refractory angina is surprisingly low

Death rates associated with patients with refractory angina, or chronic chest pain, are lower than previously considered; therefore, physicians should focus on relieving the chest pain symptoms and improving the quality of life in these patients according to an article published online this week in the European Heart Journal.

16 May 2013

Study finds novel delivery method that helps dissolve stroke-causing clots

A new study from the University of Cincinnati has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots than the standard of care, recombinant tissue plasminogen activator (rt-PA).

16 May 2013

Finding targets prostate patients who would not benefit from cancer-detecting biopsy

UC Irvine Health urologists and health policy experts report in a new study that two written assessments that identify existing comorbidities - the patient-reported Total Illness Burden Index for Prostate Cancer (TIBI-Cap) and the physician-reported Charlson Comorbidity Index - can successfully target prostate patients who would not benefit from biopsy to discover possible cancer.

16 May 2013

Simponi injection gets FDA approval to treat adults with ulcerative colitis

The U.S. Food and Drug Administration today approved a new use for Simponi (golimumab) injection to treat adults with moderate to severe ulcerative colitis.

16 May 2013

Research breakthrough: Human skin cells becomes embryonic stem cells

Scientists at Oregon Health & Science University and the Oregon National Primate Research Center have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body.

16 May 2013

Prostate cancer drug Xofigo gets FDA approval

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs.

16 May 2013

Kinesia ProView™ launched to visualize motor symptom severity response to deep brain stimulation (DBS) in Parkinson’s patients

Great Lakes NeuroTechnologies announced today the product launch of Kinesia ProView™ to visualize motor symptom severity response during programming of deep brain stimulation (DBS) for Parkinson’s disease. Kinesia ProView provides a standardized platform to quantitatively assess how symptoms such as tremor, bradykinesia, and dyskinesias change in response to specific DBS settings during outpatient programming procedures.

15 May 2013

Study shows drama therapy improves mood and reduces pain for hemodialysis patients

For patients with kidney failure, getting creative may provide some relief. Kansas State University researchers are exploring the effects of drama therapy on patients undergoing chronic hemodialysis and are the first in the world to study the topic.

15 May 2013

Researchers demonstrate how EGF accelerates division of cell nucleus

Biologists at Heidelberg University have discovered new approaches for the treatment of cancer. They investigated how a special signalling molecule, the epidermal growth factor (EGF), stimulates the separation of chromosomes in the cell. The researchers were able to demonstrate that EGF accelerates the division of the cell nucleus, i.e. mitosis, as well as boosts precision in chromosome segregation.

15 May 2013

Novel drug may increase the effectiveness of radiation therapy for brain cancer

A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma multiforme (GBM), the new drug helped significantly extend survival when used in combination with radiation therapy.

15 May 2013

Therapy News and Research

Research reveals vitamin C does not reduce urate levels in gout patients

Research shows new neural circuits arise when hippocampus is disabled

Cedars-Sinai launches new clinical trial to study effects of cabozantinib in prostate cancer patients

Preclinical study shows PLX cells may help reverse symptoms associated with preeclampsia

Study reveals that prolonged Dkk1 signaling can lead to fibrosis, stiffening of artery walls

Sonendo unveils Multisonic Ultracleaning System at AAE meeting

Scientists reveal inside story of European regulatory review and approval of Glybera

People suffering from PTSD have risk of developing type 2 diabetes

Idelalisib phase 1 clinical trial shows positive results in patients with CLL

Study underscores new paradigm in cancer therapy

Study: Long-term mortality in patients with refractory angina is surprisingly low

Study finds novel delivery method that helps dissolve stroke-causing clots

Finding targets prostate patients who would not benefit from cancer-detecting biopsy

Simponi injection gets FDA approval to treat adults with ulcerative colitis

Research breakthrough: Human skin cells becomes embryonic stem cells

Prostate cancer drug Xofigo gets FDA approval

Kinesia ProView™ launched to visualize motor symptom severity response to deep brain stimulation (DBS) in Parkinson’s patients

Study shows drama therapy improves mood and reduces pain for hemodialysis patients

Researchers demonstrate how EGF accelerates division of cell nucleus

Novel drug may increase the effectiveness of radiation therapy for brain cancer

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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