Dengue Fever News and Research

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Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash.

Inviragen to initiate second stage of DENVax Phase 2 study in dengue

Inviragen, Inc. today announced the initiation of the second stage of an ongoing Phase 2, randomized, double-blind, placebo-controlled study of DENVax, the Company's investigational dengue vaccine.

27 Feb 2013

Dengue fever mosquitoes tap into domestic networks of humans, along with their bloodstreams

The mosquitoes that spread dengue fever tap into the domestic networks of humans, along with their bloodstreams, finds a study recently published in the Proceedings of the National Academy of Sciences (PNAS).

28 Jan 2013

Brazilian city declares health emergency due to dengue fever outbreak

"Municipal authorities in Campo Grande, the capital of the southwestern Brazilian state of Mato Grosso do Sul, on Monday declared a health emergency due to a serious outbreak of dengue fever," Fox News Latino reports.

24 Jan 2013

NIH's candidate vaccine safe in treating dengue

A candidate dengue vaccine developed by scientists at the National Institutes of Health (NIH) has been found to be safe and to stimulate a strong immune response in most vaccine recipients, according to results from an early-stage clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH. The trial results were published online on January 17 in the Journal of Infectious Diseases.

23 Jan 2013

NanoViricides to advance influenza drug candidate with completed $5M funding

NanoViricides, Inc., announced today that it has received the final tranche of $2.5M from Seaside 88, LP, thereby completing the total of a $5M financing. This raise, and the receipt of the initial $2.5M tranche, was previously announced on June 29, 2012.

25 Dec 2012

Reviewing G-FINDER report findings

Nick Chapman, a policy analyst at Policy Cures, writes in a guest post on the Global Health Technologies Coalition's "Breakthroughs" blog about "the results of the latest G-FINDER survey on global funding of [research and development (R&D)] for neglected diseases."

21 Dec 2012

Study investigates different approaches to eradicate mosquito-borne diseases

A special issue of Pathogens and Global Health, published by Maney Publishing, investigates different approaches to eradicate mosquito-borne diseases. Mosquitoes can transmit a number of pathogenic diseases including dengue fever, yellow fever, and malaria.

13 Dec 2012

Broad range of human activities affects spread of vector-borne zoonotic diseases, experts say

West Nile virus, Lyme disease, dengue fever, and plague are examples of "vector-borne zoonotic diseases," caused by pathogens that naturally infect wildlife and are transmitted to humans by vectors such as mosquitoes or ticks.

30 Nov 2012

DiscoGnosis project aims to develop rapid malaria test

An estimated 500 million people become infected with malaria each year. The disease is often lethal - particularly in tropical developing countries with insufficient health care services. The infected suffer from a high fever. As this is also the case with other germs, however, it is important to conduct a rapid and precise analysis to determine the cause of the disease for a successful therapy.

22 Nov 2012

HCV medications' side effects can now be replicated and observed in Petri dishes and test tubes

The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg Professor of Biochemistry and Molecular Biology at Penn State University.

17 Nov 2012

Growing number of dengue cases in India increases risk of disease spreading worldwide, experts warn

"An epidemic of dengue fever in India is fostering a growing sense of alarm even as government officials here have publicly refused to acknowledge the scope of a problem that experts say is threatening hundreds of millions of people, not just in India but around the world," the New York Times reports.

8 Nov 2012

New method of testing for West Nile virus

While the United States has largely been spared the scourge of mosquito-borne diseases endemic to the developing world-including yellow fever, malaria and dengue fever-mosquito-related illnesses in the US are on the rise. One pathogen of increasing concern in the U.S. is an arbovirus known as West Nile.

24 Oct 2012

Biologists unravel why some people infected with HIV have more virus

Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams than others.

24 Sep 2012

Health experts warn of linkages between climate change, increased malnutrition

"Malnutrition is likely to be the most serious health threat linked to climate shifts in the coming decades, as farmers struggle to cope with more unpredictable weather, ... epidemiologist Kris Ebi warned during a recent World Health Organization (WHO) briefing on adapting health systems to climate shifts," AlertNet reports.

20 Sep 2012

Number of recorded dengue cases up 36% over last year in Costa Rica

"A total of 8,480 people have been affected by dengue fever in Costa Rica" so far this year, representing an increase of 36 percent, or 2,230 more cases than during the same period last year, according to a Ministry of Health report, Xinhua News reports.

19 Sep 2012

Clinical trial results signal 'promise, unresolved challenges' in finding effective dengue vaccine

The first-ever results from a dengue virus vaccine clinical trial aimed at showing effectiveness "provide signals rather than definitive answers, and a mixture of both promise and unresolved challenges," Orin Levine, executive director of the International Vaccine Access Center, and Ciro de Quadros, executive vice president of the Sabin Vaccine Institute, write in the Huffington Post "Impact" blog.

14 Sep 2012

Breakthrough for dengue vaccine development

A live-attenuated vaccine against the four strains of dengue virus known as CYD-TDV has demonstrated promising efficacy in a phase IIb trial.

12 Sep 2012

Leading dengue fever vaccine candidate 30% effective in first large clinical trial

"The leading candidate to become the world's first vaccine against dengue fever was only 30 percent effective in its first large clinical trial, dealing at least a temporary setback to efforts to control a disease that threatens half the world's population," the New York Times reports.

12 Sep 2012

Dengue vaccine breakthrough

Results of the first ever trial to show that a safe and effective dengue vaccine may be possible are published Online First in The Lancet.

11 Sep 2012

WHO releases dengue strategy report, sets goal of cutting related deaths in half by 2020

"Saying dengue virus infections and deaths have mushroomed in recent years, the World Health Organization (WHO) recently released a strategy report that sets a goal of cutting deaths in half and reducing cases by 25 percent over the next eight years," CIDRAP reports.

6 Sep 2012