Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Genetic signals reveal why erectile dysfunction develops and who is most at risk

This multi-ancestry genomic study identifies key genetic loci underlying erectile dysfunction and shows that ED risk is shaped by both cardiometabolic and substance use–related genetic pathways. Using EHR-linked data, the researchers uncover SIM1-related mechanisms, modest PRS performance, and bidirectional genetic links with obesity, diabetes, and addiction traits.

25 Nov 2025

Deep learning AI model identifies first-of-its-kind biomarker of chronic stress

Using a deep learning AI model, researchers identified the first-of-its-kind biomarker of chronic stress detectable through routine imaging, according to research being presented next week at the annual meeting of the Radiological Society of North America.

25 Nov 2025

Digital and AI innovations in cardiology take center stage at ESC Digital & AI Summit

Smartphone stethoscopes, voice-detected heart failure, training using 3D-printed and virtual hearts and early detection of cardiovascular disease using blood spots are among the innovations being presented at the ESC Digital & AI Summit taking place in Berlin, Germany, 21–22 November.

21 Nov 2025

Even one cigarette a day harms the heart at every level

Smoking elevates heart disease and mortality risks. Cessation initiates a powerful recovery, reducing risks significantly within two decades.

21 Nov 2025

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

GLP-1 receptor agonists improve glycaemic control and provide renal, metabolic, and selective cardiovascular benefits in people with type 2 diabetes, based on an umbrella review of 17 meta-analyses. However, these agents consistently increase gastrointestinal adverse effects and show important distinctions between class-level outcomes and individual drug effects, particularly for semaglutide.

20 Nov 2025

New patch may help heal the heart after a heart attack

A new patch developed by Texas A&M University researcher Dr. Ke Huang may offer a way to help the heart heal after a heart attack.

19 Nov 2025

Study reveals the long-lasting health impacts of eating disorders

The health impacts of eating disorders, such as anorexia, bulimia, and binge eating, are not only complex, affecting many different organ systems, but long-lasting, finds a large tracking study, published in the open access journal BMJ Medicine.

19 Nov 2025

Even minimal cigarette use significantly increases heart disease and mortality risk

Smoking even 2-5 cigarettes a day can more than double your risk of any type of heart disease and raise your risk of death from any cause by 60% compared to people who never smoked, according to new research supported by the American Heart Association's Tobacco Center for Regulatory Science and published in PLOS Medicine.

19 Nov 2025

Current genetic screening guidelines overlook most cases of familial hypercholesterolemia

Current genetic screening guidelines fail to identify most people with an inherited condition known as familial hypercholesterolemia that can cause dangerously high cholesterol and early heart disease, a Mayo Clinic study found.

19 Nov 2025

Analysis finds even low-intensity smokers have higher risk of heart disease and death

An analysis of data from almost two dozen long-term studies finds that even low-intensity smokers have a substantially higher risk of heart disease and death compared to people who never smoked, even years after they quit.

18 Nov 2025

American Heart Association expands effort to improve hypertrophic cardiomyopathy care

Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease and impacts an estimated 1 in 500 people in the U.S., according to the American Heart Association, a relentless force changing the future of health for everyone everywhere.

17 Nov 2025

Calculator assesses 30-year heart risk for young adults

Just as saving for retirement starts early, so should protecting your heart. A new Northwestern Medicine study introduces a first-of-its-kind online calculator that uses percentiles to help younger adults forecast and understand their risk of a heart event over the next 30 years.

17 Nov 2025

Why early- and late-onset depression are fundamentally different

Genetic differences in early- and late-onset depression highlight distinct risk profiles, informing targeted strategies for improved clinical outcomes.

17 Nov 2025

Dash diet cuts diabetes complications by targeting blood pressure kidney health and inflammation

The DASH diet supports metabolic health in people with diabetes by improving blood pressure, renal function, lipids, and modest glycemic markers while reducing risks linked to vascular and inflammatory pathways. Its broad nutrient-driven mechanisms also benefit related conditions such as neuropathy, PCOS, and retinopathy, making it a versatile tool for cardiometabolic care.

16 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

Cardiologists recommend reassessing need for additional stents later

A blocked coronary artery causing an acute heart attack must be opened immediately with a stent procedure. However, if other coronary arteries also appear to be narrowed, it is safe to wait and treat those later. This approach cuts the number of stent procedures in half, according to cardiologists from Radboud university medical center, writing in The New England Journal of Medicine.

14 Nov 2025

Family support helped adults in rural China to reduce blood pressure levels

New research found family support helped adults in rural China reduce their blood pressure.

13 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025

Plant-based diet prevents and reverses heart microvascular dysfunction in hypertensive rats

Eating a plant-based diet consisting of fruits, vegetables, nuts and legumes can help prevent and reverse heart disease in rats that have high blood pressure, according to a study published by researchers in the Institute for Biomedical Sciences at Georgia State University.

12 Nov 2025

Northwestern scientists create new genetic risk score to improve prediction of arrhythmia

In a new Northwestern Medicine study, scientists have developed a more precise genetic risk score to determine whether a person is likely to develop arrhythmia, an irregular heartbeat that can lead to serious conditions such as atrial fibrillation (AFib) or sudden cardiac death.

11 Nov 2025

Heart Failure News and Research

Further Reading

Genetic signals reveal why erectile dysfunction develops and who is most at risk

Deep learning AI model identifies first-of-its-kind biomarker of chronic stress

Digital and AI innovations in cardiology take center stage at ESC Digital & AI Summit

Even one cigarette a day harms the heart at every level

Study compares GLP-1 drug benefits and finds substantial variation in clinical effects

New patch may help heal the heart after a heart attack

Study reveals the long-lasting health impacts of eating disorders

Even minimal cigarette use significantly increases heart disease and mortality risk

Current genetic screening guidelines overlook most cases of familial hypercholesterolemia

Analysis finds even low-intensity smokers have higher risk of heart disease and death

American Heart Association expands effort to improve hypertrophic cardiomyopathy care

Calculator assesses 30-year heart risk for young adults

Why early- and late-onset depression are fundamentally different

Dash diet cuts diabetes complications by targeting blood pressure kidney health and inflammation

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Cardiologists recommend reassessing need for additional stents later

Family support helped adults in rural China to reduce blood pressure levels

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Plant-based diet prevents and reverses heart microvascular dysfunction in hypertensive rats

Northwestern scientists create new genetic risk score to improve prediction of arrhythmia

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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