Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Researchers develop scale to assess antibiotic resistance awareness among healthcare professionals

Researchers developed an antibiotic resistance (ABR) awareness scale to assess ABR awareness among human healthcare professionals (HHCPs) and animal healthcare professionals (AHCPs).

30 Jan 2023

Studying the HIV response for pandemic preparedness

Researchers assessed the impact of utilizing the human immunodeficiency virus (HIV) response in improving pandemic preparedness.

27 Jan 2023

Exploring the contribution of COVID-19 prevention network to SARS-CoV-2 vaccine efficacy clinical trials

Researchers described the coronavirus disease 2019 (COVID-19) prevention network (CoVPN) and its contribution to clinical efficacy evaluations of COVID-19 vaccines in phase 3 trials.

25 Jan 2023

A slight increase in Mpox cases across the globe, along with an increase in deaths

The WHO discusses genomic sequencing of the Mpox virus, in addition to providing public and clinical health links between HIV and Mpox.

24 Jan 2023

Researchers review the association between endogenous retrovirus reactivation and aging

Researchers explored the role of endogenous retrovirus (ERV) reactivation in the aging process.

24 Jan 2023

Review on lateral flow test use spearheaded by SARS-CoV-2 pandemic

Researchers assessed the changing landscape of lateral flow tests (LFTs), and the development of next-generation LFTs based on lessons learnt from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.

23 Jan 2023

WHO’s 14th situation report for the multi-country outbreak of mpox overviews the clinical and public health links between HIV and mpox

In the present report, researchers reported the most recent findings of MPXV infections.

23 Jan 2023

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.

23 Jan 2023

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

In a recent study published in The Lancet Microbe journal, researchers described the effectiveness of a modular capsid virus-like coronavirus disease 2019 (COVID-19) vaccination.

22 Jan 2023

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Researchers performed an epidemic dynamic analysis to assess the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)’s sub-VOC XBB.1.5 characteristics.

19 Jan 2023

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

A new study describes that tight transmission bottlenecks restrict the evolution of SARS-CoV-2 in the transmission chain. SARS-CoV-2 is the causative pathogen of the COVID-19 pandemic.

18 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

Researchers develop innovative STAb therapy for a type of leukemia

Researchers of the Hospital Universitario 12 de Octubre in Madrid and the Josep Carreras Leukaemia Research Institute have developed a cell therapy for a type of leukemia which currently has very few treatment options.

16 Jan 2023

Recent findings on original antigenic sin and SARS-CoV-2

Researchers collated the findings of studies relating original antigenic sin with SARS-CoV-2 evolution.

13 Jan 2023

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Researchers discovered that the spike protein of SARS-CoV-2 is susceptible to cleavage at the disulfide bonds, and the vulnerability to reductive cleavage varies across variants, with the Omicron variant family being highly susceptible to reduction.

10 Jan 2023

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Researchers presented the results of a phase III randomized controlled trial of oral SARS-CoV-2 antiviral VV116.

3 Jan 2023

Scientists explore synthesis of griffithsin in cell-free systems

A new study described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein.

28 Dec 2022

An estimated 19 million US adults living with long-COVID

In a recent study published in the journal Clinical Infectious Diseases, a team of researchers examined the risk factors and prevalence and impact of long coronavirus disease (COVID) among a representative sample of adults in the United States (U.S.) and reported that close to 19 million U.S. adults suffer from long COVID.

26 Dec 2022

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

A recent Nature Cancer study documented that individuals with B cell lymphomas (LY) and multiple myeloma (MM) developed potent infection neutralization capabilities against several SARS-CoV-2 variants of concern (VoCs).

22 Dec 2022

WHO releases a global strategy for infection prevention and control at the 75th World Health Assembly

A recent draft released by the World Health Organization discussed the new global strategy to address the gaps in infection prevention and control (IPC) programs that became apparent after the coronavirus disease 2019 (COVID-19) pandemic.

21 Dec 2022

Immunodeficiency News and Research

Further Reading

Researchers develop scale to assess antibiotic resistance awareness among healthcare professionals

Studying the HIV response for pandemic preparedness

Exploring the contribution of COVID-19 prevention network to SARS-CoV-2 vaccine efficacy clinical trials

A slight increase in Mpox cases across the globe, along with an increase in deaths

Researchers review the association between endogenous retrovirus reactivation and aging

Review on lateral flow test use spearheaded by SARS-CoV-2 pandemic

WHO’s 14th situation report for the multi-country outbreak of mpox overviews the clinical and public health links between HIV and mpox

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers develop innovative STAb therapy for a type of leukemia

Recent findings on original antigenic sin and SARS-CoV-2

Spike protein mutations in Omicron subvariants increase their susceptibility to reductive cleavage of disulfide bonds

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Scientists explore synthesis of griffithsin in cell-free systems

An estimated 19 million US adults living with long-COVID

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

WHO releases a global strategy for infection prevention and control at the 75th World Health Assembly

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